PT J
AU Greenlee, H
   Crew, KD
   Capodice, J
   Awad, D
   Buono, D
   Shi, Z
   Jeffres, A
   Wyse, S
   Whitman, W
   Trivedi, MS
   Kalinsky, K
   Hershman, DL
AF Greenlee, Heather
   Crew, Katherine D
   Capodice, Jillian
   Awad, Danielle
   Buono, Donna
   Shi, Zaixing
   Jeffres, Anne
   Wyse, Sharon
   Whitman, Wendy
   Trivedi, Meghna S
   Kalinsky, Kevin
   Hershman, Dawn L
TI Randomized sham-controlled pilot trial of weekly electro-acupuncture for the
SO Breast cancer research and treatment
LA English
DT Journal Article
DE Acupuncture; Breast cancer; Chemotherapy-induced peripheral neuropathy; Electro-acupuncture; Taxane
AB To investigate the effect of electro-acupuncture (EA) as a non-pharmacological  intervention to prevent or reduce chemotherapy-induced peripheral neuropathy  (CIPN) in breast cancer patients undergoing chemotherapy of taxane. Women with  stage I-III breast cancer scheduled to receive taxane therapy were randomized to  receive a standardized protocol of 12 true or sham EA (SEA) weekly treatments  concurrent with taxane treatment. Subjects completed the Brief Pain  Inventory-Short Form (BPI-SF), Functional Assessment of Cancer Therapy-Taxane  neurotoxicity subscale (FACT-NTX), and other assessments at baseline and weeks 6,  12, and 16. A total of 180 subjects were screened, 63 enrolled and 48 completed  week 16 assessments. Mean age was 50 with 25 % white, 25 % black, and 43 %  Hispanic; 52 % had no prior chemotherapy. At week 12, both groups reported an  increase in mean BPI-SF worst pain score, but no mean differences were found  between groups (SEA 2.8 vs. EA 2.6, P = .86). By week 16, the SEA group returned  to baseline, while the EA group continued to worsen (SEA 1.7 vs. EA 3.4, P =  .03). The increase in BPI-SF worst pain score was 1.62 points higher in the EA  group than in the SEA group at week 16 (P = .04). In a randomized,  sham-controlled trial of EA for prevention of taxane-induced CIPN, there were no  differences in pain or neuropathy between groups at week 12. Of concern, subjects  on EA had a slower recovery than SEA subjects. Future studies should focus on EA  for treatment as opposed to prevention of CIPN.
C1 Mailman School of Public Health, Columbia University, New York, NY, USA. hg2120@columbia.edu.
   Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, 
   Columbia University, 722 W. 168th Street, Room 733, New York, NY, 10032, USA. hg2120@columbia.edu.
   Mailman School of Public Health, Columbia University, New York, NY, USA.
   Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, 
   College of Physicians and Surgeons, Columbia University, New York, NY, USA.
   Mount Sinai School of Medicine, New York, NY, USA.
   Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, USA.
   College of Physicians and Surgeons, Columbia University, New York, NY, USA.
   Mailman School of Public Health, Columbia University, New York, NY, USA.
   Mailman School of Public Health, Columbia University, New York, NY, USA.
   Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, USA.
   Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, USA.
   Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, USA.
   College of Physicians and Surgeons, Columbia University, New York, NY, USA.
   Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, USA.
   College of Physicians and Surgeons, Columbia University, New York, NY, USA.
   Mailman School of Public Health, Columbia University, New York, NY, USA.
   Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, 
   College of Physicians and Surgeons, Columbia University, New York, NY, USA.
NR 0
TC 0
SN 1573-721
EI 0167-680
J9 Breast Cancer Res Treat
PD MAR 26
PY 2016
VL 156
IS 3
BP 453
EP 464
DI 10.1007/s10549-016-3759-2
PG 11
WC Adult; Aged; Breast Neoplasms; drug therapy; Bridged-Ring Compounds; adverse effects; Double-Blind Method; Electroacupuncture; methods; Female; Humans; Middle Aged; Peripheral Nervous System Diseases; chemically induced; Pilot Projects; Taxoids; adverse effects; Treatment Outcome
UT PubMed:27013473
PM 27013473
DA 2016-03-26
ER

PT J
AU Dommerholt, J
   Finnegan, M
   Hooks, T
   Grieve, R
AF Dommerholt, Jan
   Finnegan, Michelle
   Hooks, Todd
   Grieve, Rob
TI A critical overview of the current myofascial pain literature - September 2016.
SO Journal of bodywork and movement therapies
LA English
DT Review
DE Dry needling; Manual therapy; Myofascial pain syndrome; Trigger points
AB This edition of the overview of the current myofascial pain literature includes  24 studies, case reports and systematic and narrative reviews. Surprisingly, five  of the 24 papers were difficult to read and interpret mostly because of a poor  mastery of the English language. It is somewhat surprising that journal editors  and reviewers would accept papers that are needlessly difficult to read and not  direct the authors to language services or others who could improve the quality  of the writings. Of course, it is exciting that researchers and clinicians from  all over the world continue to focus on myofascial pain and attempt to shed new  light on the complexity of the problem to improve the clinical decision-making  process and eventually clinical approaches and outcomes. There were no new papers  on manual therapies, but many focused on dry needling.
C1 Bethesda Physiocare, Bethesda, MD, USA
   Myopain Seminars, Bethesda, MD, USA. 
   Bethesda Physiocare, Bethesda, MD, USA
   Myopain Seminars, Bethesda, MD, USA. 
   New Orleans Pelicans, New Orleans, LA, USA. 
   Department of Allied Health Professions, Faculty of Health and Applied Sciences, University of the West of England, Blackberry Hill, Bristol, United Kingdom.
EM Rob.Grieve@uwe.ac.uk
NR 0
TC 0
SN 1532-928
EI 
J9 J Bodyw Mov Ther
PD NOV 7
PY 2016
VL 20
IS 4
BP 879
EP 892
DI 10.1016/j.jbmt.2016.09.010
PG 13
WC Acupuncture Therapy; methods; Electric Stimulation Therapy; methods; Humans; Musculoskeletal Manipulations; methods; Myofascial Pain Syndromes; diagnosis; Needles; Neoplasms; therapy; Observer Variation; Pain Management; methods; Pain Measurement; Physical Therapy Modalities; Reaction Time; Reproducibility of Results; Shoulder Pain; therapy; Temporomandibular Joint Disorders; diagnosis; Trigger Points; Veterans
UT PubMed:27814870
PM 27814870
DA 2016-11-07
ER

PT J
AU Bauer, BA
   Tilburt, JC
   Sood, A
   Li, GX
   Wang, SH
AF Bauer, Brent A.
   Tilburt, Jon C.
   Sood, Amit
   Li Guang-xi
   Wang Shi-han
TI Complementary and alternative medicine therapies for chronic pain
SO CHINESE JOURNAL OF INTEGRATIVE MEDICINE
LA English
DT Article
DE complementary and alternative medicine; therapy; chronic pain; safety and effificacy
ID low-back-pain; massage therapy; herbal medicines; self-management; acupuncture; placebo; metaanalysis; efficacy; cancer; biofeedback
AB Pain afflflicts over 50 million people in the US, with 30.7% US adults suffering with chronic pain. Despite advances in therapies, many patients will continue to deal with ongoing symptoms that are not fully addressed by the best conventional medicine has to offer them. The patients frequently turn to therapies outside the usual purview of conventional medicine (herbs, acupuncture, meditation, etc.) called complementary and alternative medicine (CAM). Academic and governmental groups are also starting to incorporate CAM recommendations into chronic pain management strategies. Thus, for any physician who care for patients with chronic pain, having some familiarity with these therapies-including risks and benefits-will be key to helping guide patients in making evidence-based, well informed decisions about whether or not to use such therapies. On the other hand, if a CAM therapy has evidence of both safety and efficacy then not making it available to a patient who is suffering does not meet the need of the patient. We summarize the current evidence of a wide variety of CAM modalities that have potential for helping patients with chronic pain in this article. The triad of chronic pain symptoms, ready access to information on the internet, and growing patient empowerment suggest that CAM therapies will remain a consistent part of the healthcare of patients dealing with chronic pain.
C1 [Bauer, Brent A.; Tilburt, Jon C.; Sood, Amit] Mayo Clin, Div Complementary & Integrat Med, Rochester, MN 55905 USA.
   [Li Guang-xi] Mayo Clin, Div Pulm & Crit Care Med, Rochester, MN 55905 USA.
   [Li Guang-xi; Wang Shi-han] China Acad Chinese Med Sci, Guanganmen Hosp, Beijing 100053, Peoples R China.
   [Wang Shi-han] Mayo Clin, Div Cardiovasc Dis, Rochester, MN 55905 USA.
C3 Mayo Clinic; Mayo Clinic; China Academy of Chinese Medical Sciences; Guang'anmen Hospital, CACMS; Mayo Clinic
RP Bauer, BA (corresponding author), Mayo Clin, Div Complementary & Integrat Med, Rochester, MN 55905 USA.
EM Bauer.brent@mayo.edu
FU Thorne Research
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NR 89
TC 54
Z9 64
U1 0
U2 30
PU SPRINGER
PI NEW YORK
PA ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES
SN 1672-0415
EI 1993-0402
J9 CHIN J INTEGR MED
JI Chin. J. Integr. Med.
PD JUN 15
PY 2016
VL 22
IS 6
BP 403
EP 411
DI 10.1007/s11655-016-2258-y
PG 9
WC Integrative & Complementary Medicine
SC Integrative & Complementary Medicine
GA DQ2DH
UT WOS:000379011200001
PM 27339090
DA 2026-01-16
ER

PT J
AU McVicar, A
   Greenwood, C
   Ellis, C
   LeForis, C
AF McVicar, Andrew
   Greenwood, Christina
   Ellis, Carol
   LeForis, Chantelle
TI Influence of Study Design on Outcomes Following Reflexology Massage: An Integrative and Critical Review of Interventional Studies
SO JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE
LA English
DT Review
ID randomized controlled-trial; quality-of-life; foot reflexology; multiple-sclerosis; clinical-trials; breast-cancer; pain; complementary; efficacy; acupuncture
AB Background: Interpretation of the efficacy of reflexology is hindered by inconsistent research designs and complicated by professional views that criteria of randomized controlled trials (RCTs) are not ideal to research holistic complementary and alternative medicine practice. The influence of research designs on study outcomes is not known. This integrative review sought to evaluate this possibility. Materials and Methods: Thirty-seven interventional studies (2000-2014) were identified; they had RCT or non-RCT design and compared reflexology outcomes against a control/comparison group. Viability of integrating RCT and non-RCT studies into a single database was first evaluated by appraisal of 16 reporting fields related to study setting and objectives, sample demographics, methodologic design, and treatment fidelity and assessment against Jadad score quality criteria for RCTs. For appraisal, the database was stratified into RCT/non-RCT or Jadad score of 3 or more or less than 3. Deficits in reporting were identified for blind assignment of participants, dropout/completion rate, and School of Reflexology. For comparison purposes, these fields were excluded from subsequent analysis for evidence of association between design fields and of fields with study outcomes. Results: Thirty-one studies applied psychometric tools and 20 applied biometric tools (14 applied both). A total of 116 measures were used. Type of measure was associated with study objectives (p < 0.001; chi-square), in particular of psychometric measures with a collated "behavioral/cognitive" objective. Significant outcomes were more likely (p < 0.001; chi-square) for psychometric than for biometric measures. Neither type of outcome was associated with choice of RCT or non-RCT method, but psychometric responses were associated (p = 0.007) with a nonmassage control strategy. Conclusions: The review supports psychometric responses to reflexology when study design uses a nonmassage control strategy. Findings suggest that an evaluation of outcomes against sham reflexology massage and other forms of massage, as well as a narrower focus of study objective, may clarify whether there is a relationship between study design and efficacy of reflexology.
C1 [McVicar, Andrew; LeForis, Chantelle] Anglia Ruskin Univ, Fac Hlth Social Care & Educ, Bishop Hall Lane, Chelmsford CM1 15Q, Essex, England.
   [Greenwood, Christina; Ellis, Carol] Anglia Ruskin Univ, Fac Med Sci, Chelmsford, Essex, England.
C3 Anglia Ruskin University; Anglia Ruskin University
RP McVicar, A (corresponding author), Anglia Ruskin Univ, Fac Hlth Social Care & Educ, Bishop Hall Lane, Chelmsford CM1 15Q, Essex, England.
EM Andy.McVicar@anglia.ac.uk
FU Anglia Ruskin University, United Kingdom
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NR 59
TC 5
Z9 7
U1 0
U2 14
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 1075-5535
EI 1557-7708
J9 J ALTERN COMPLEM MED
JI J. Altern. Complement Med.
PD SEP 15
PY 2016
VL 22
IS 9
BP 739
EP 750
DI 10.1089/acm.2016.0015
PG 12
WC Integrative & Complementary Medicine
SC Integrative & Complementary Medicine
GA DW9SL
UT WOS:000384002900010
PM 27463943
DA 2026-01-16
ER

PT J
AU Heo, JS
   Yang, SY
   Lim, SA
   Lee, JM
   Kang, JY
   Sun, SH
   Kim, HG
   Kang, W
   Cho, JH
AF Heo, Je-Sin
   Yang, Su-Young
   Lim, Sung-Ah
   Lee, Jong-Moo
   Kang, Ji-Young
   Sun, Seung-Ho
   Kim, Hyeong-Geug
   Kang, Weechang
   Cho, Jung-Hyo
TI A manual acupuncture treatment attenuates common cold and its symptoms: a case series report from South Korea
SO JOURNAL OF TRADITIONAL CHINESE MEDICINE
LA English
DT Article
DE Common cold; Hand acupuncture; Traditional Chinese Medicine therapy; Case reports
ID randomized controlled-trial; sufficiently important difference; cancer; pain; infection; influenza; severity; cost
AB OBJECTIVE: To investigate beneficial effects of manual acupuncture on common cold periods and its symptoms depended on the difference onset time of common cold, within 36 h or over than that. To prove effects of manual acupuncture on common cold, a retrospective chart review was conducted. METHODS: Chart data for patients with common cold who were treated with only manual acupuncture with fulfilling Jackson scales and satisfaction at the end of each treatment were collected via multi-centers of Oriental hospitals, Oriental medicine clinics and covalent hospital in South Korea. Totally 187 patients were divided into two groups, Group I (115 patients, within 36 h) and Group II (72 patients, onset time of cold over than 36 h). Finally 120 patients were observed until entire resolution of cold symptoms. RESULTS: Group I showed significant decreases the median durations of completely recovery (3 days; 95% CI 3.0-4.0) as compared with Group II (6 days; 95% CI 4.0-7.0, P < 0.001). The manual acupuncture beneficially worked for reduction rate of common cold symptoms by 50% after initial treatment, decreased cold symptoms, and reduced cold duration. CONCLUSION: Manual acupuncture beneficially affected common cold and its symptoms. Moreover it is more susceptibility on the early time of onset cold. (C) 2016 JTCM. All rights reserved.
C1 [Heo, Je-Sin; Yang, Su-Young; Lee, Jong-Moo] Assoc Sang Su Med, Dept Acupuncture Therapy, Daejeon 301805, South Korea.
   [Lim, Sung-Ah] Daejeon Univ, Dept Beauty & Hlth Care, Coll Sports & Hlth Publ, Daejeon 300716, South Korea.
   [Kang, Ji-Young; Kim, Hyeong-Geug; Cho, Jung-Hyo] Daejeon Univ, Dept Internal Immune Ctr, Daejeon Oriental Hosp, Daejeon 301724, South Korea.
   [Sun, Seung-Ho] Sangji Univ, Dept Internal Med, Korean Med Hosp, Kangwon 220955, South Korea.
   [Kang, Weechang] Daejeon Univ, Dept Business Informat Stat, Coll Business Adm, Daejeon 300716, South Korea.
C3 Daejeon University; Daejeon University; Sangji University; Daejeon University
RP Cho, JH (corresponding author), Daejeon Univ, Dept Internal Immunol Ctr, Daejeon Oriental Hosp, Daejeon 301724, South Korea.
EM choa-joa@dju.kr
FU Educational Research (the Project of Intramural Research Supporting Program) from Daejeon University [201400950001]; Study of Acupuncture Therapy in Traditional Korean Medicine (Theory of the Acupuncture Lecture in South Korea) [2014-001A]
CR Arroll B, 2005, COCHRANE DB SYST REV, V6, P0
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NR 24
TC 0
Z9 2
U1 0
U2 8
PU JOURNAL TRADITIONAL CHINESE MED
PI BEIJING
PA 16 NANXIAOJIE, DONGZHIMEN NEI, BEIJING, 100700, PEOPLES R CHINA
SN 0255-2922
EI 1577-7014
J9 J TRADIT CHIN MED
JI J. Tradit. Chin. Med.
PD DEC 15
PY 2016
VL 36
IS 6
BP 724
EP 729
DI 10.1016/S0254-6272(17)30006-7
PG 6
WC Integrative & Complementary Medicine
SC Integrative & Complementary Medicine
GA EF1LU
UT WOS:000390087100006
PM 29949334
DA 2026-01-16
ER

PT J
AU Gjeorgjievski, M
   Manickam, P
   Ghaith, G
   Cappell, MS
AF Gjeorgjievski, Mihajlo
   Manickam, Palaniappan
   Ghaith, Gehad
   Cappell, Mitchell S
TI Safety and Efficacy of Endoscopic Therapy for Nonmalignant Duodenal Duplication
SO Medicine
LA English
DT Review
AB Analyze efficacy, safety of endoscopic therapy for duodenal duplication cysts  (DDC) by comprehensively reviewing case reports.Tandem, independent, systematic,  computerized, literature searches were performed via PubMed using medical subject  headings or Keywords "cyst" and "duodenal" and "duplication"; or "cyst", and  "endoscopy" or "endoscopic", and "therapy" or "decompression"; with  reconciliation of generated references by two experts. Case report followed CARE  guidelines.Literature review revealed 28 cases (mean = 1.3 ± 1.2 cases/report).  Endoscopic therapy is increasingly reported recently (1984-1999: 3 cases,  2000-2015: 25 cases, P = 0.003, OR = 8.33, 95%-CI: 1.77-44.5). Fourteen (54%) of  26 patients were men (unknown-sex = 2). Mean age = 32.2 ± 18.3 years old.  Procedure indications: acute pancreatitis-16, abdominal pain-8, jaundice-2,  gastrointestinal (GI) obstruction-1, asymptomatic cyst-1. Mean maximal DDC  dimension = 3.20 ± 1.53 cm (range, 1-6.5 cm). Endoscopic techniques included cyst  puncture via needle knife papillotomy (NKP)/papillotome-18, snare resection of  cyst-7, cystotome-2, and cyst needle aspiration/ligation-1. Endoscopic therapy  was successful in all cases. Among 24 initially symptomatic patients, all  remained asymptomatic post-therapy without relapses (mean follow-up = 36.5 ± 48.6  months, 3 others reported asymptomatic at follow-up of unknown duration; 1  initially asymptomatic patient remained asymptomatic 3 years post-therapy). Two  complications occurred: mild intraprocedural duodenal bleeding related to NKP and  treated locally endoscopically.A patient is reported who presented with vomiting,  15-kg-weight-loss, and profound dehydration for 1 month from extrinsic  compression of duodenum by 14 × 6 cm DDC, underwent successful endosonographic  cyst decompression with large fenestration of cyst and endoscopic aspiration of  1 L of fluid from cyst with rapid relief of symptoms. At endoscopy the DDC was  intubated and visualized and random endoscopic mucosal biopsies were obtained to  help exclude malignant or dysplastic DDC.Study limitations include retrospective  literature review, potential reporting bias, limited patient number, variable  follow-up.In conclusion, endoscopic therapy for DDC was efficacious in all 29  reported patients including current case, including patients presenting acutely  with acute pancreatitis, or GI obstruction. Complications were rare and minor,  suggesting that endoscopic therapy may be a useful alternative to surgery for  nonmalignant DDC when performed by expert endoscopists.
C1 From the Division of Gastroenterology & Hepatology, William Beaumont Hospital (MG, PM, GG, MSC)
   and Oakland University William Beaumont School of Medicine(GG, MSC), Royal Oak, MI.
NR 0
TC 0
SN 1536-596
EI 0025-797
J9 Medicine (Baltimore)
PD JUN 4
PY 2016
VL 95
IS 22
BP e3799
EP e3799
DI 10.1097/MD.0000000000003799
PG 1
WC Adult; Cysts; diagnosis; Duodenal Diseases; diagnosis; Endoscopy; methods; Humans; Male
UT PubMed:27258515
PM 27258515
DA 2016-06-04
ER

PT J
AU Wong, R
   Major, P
   Sagar, S
AF Wong, Raimond
   Major, Pierre
   Sagar, Stephen
TI Phase 2 Study of Acupuncture-Like Transcutaneous Nerve Stimulation for Chemotherapy-Induced Peripheral Neuropathy
SO INTEGRATIVE CANCER THERAPIES
LA English
DT Article
DE chemotherapy; ALTENS; Acupuncture; TENS; neuropathy
ID pilocarpine
AB A prospective phase 2 study was conducted to evaluate the clinical utility of acupuncture-like transcutaneous nerve stimulation (ALTENS) for the treatment of chemotherapy-induced peripheral neuropathy (CIPN). Eligible cancer patients had a < 2 ECOG performance score, received neurotoxic chemotherapy, and developed CIPN symptoms for > two months. Randomization was used to eliminate bias in patient selection for ALTENS and was not to compare the effectiveness between the two treatments.ALTENS treatments were delivered using Codetron units. Bilateral acupuncture points included LI4 and LIV3, plus LI11 or ST36 were stimulated. Acupuncture treatments were administered to CV6, SP6, ST6, LI11, Bafeng, Baxie and selective Jing points bilaterally. Twelve treatments were delivered twice weekly over 6 to 8 weeks. The Modified Total Neuropathy Score (mTNS), Numbness Score, and Edmonton Symptom Assessment Score (ESAS) were assessed at baseline, treatment completion, plus at 3 and 6 months follow-up. The primary study endpoint was mTNS score at 6 months. We planned to recruit 23 patients into each group. After 30 patients were recruited, 2 were lost to follow-up at 3 months in the ALTENS group and 3 in the acupuncture group. The research team decided to recruit all remaining consecutive patients only to the ALTENS group to ensure an adequate evaluation of ALTENS, the primary object of evaluation. There were 27 patients in the ALTENS group, with an average symptom duration of 10 months after chemotherapy. Twenty four and 23 patients completed the 3 and 6 month follow-up respectively. The median mTNS scores were 7.1, 4.0, 3.6 and 3.1 at baseline, treatment completion, 3 and 6 months follow-up, respectively. One-way ANOVA analysis showed a significant improvement in mTNS scores (p<0.001) at 6 months. Numbness scores were also significantly improved at 6 months. ESAS pain scores and perception of well-being scores analyses were inconclusive. There were no significant reported side effects of ALTENS. There were only 13 patients in the acupuncture group and the number was insufficient for either an independent or a comparative analysis. The results of this study suggests that ALTENS significantly reduces the mTNS scores and numbness in patients suffering from CIPN symptoms.
C1 [Wong, Raimond; Major, Pierre; Sagar, Stephen] McMaster Univ, Juravinski Canc Ctr, Hamilton, ON, Canada.
C3 McMaster University
RP Wong, R (corresponding author), Juravinski Canc Ctr, Dept Radiat Oncol, 699 Concess St, Hamilton, ON L8V 5C2, Canada.
EM wongrai@hhsc.ca
FU Lotte & John Hecht Memorial Foundation, Vancouver, Canada
CR Avan A, 2015, ONCOLOGIST, V20, P411, DOI 10.1634/theoncologist.2014-0044
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NR 17
TC 28
Z9 30
U1 1
U2 24
PU SAGE PUBLICATIONS INC
PI THOUSAND OAKS
PA 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
SN 1534-7354
EI 1552-695X
J9 INTEGR CANCER THER
JI Integr. Cancer Ther.
PD JUN 15
PY 2016
VL 15
IS 2
BP 153
EP 164
DI 10.1177/1534735415627926
PG 12
WC Oncology; Integrative & Complementary Medicine
SC Oncology; Integrative & Complementary Medicine
GA DM4HC
UT WOS:000376306900003
PM 27130723
DA 2026-01-16
ER

PT J
AU Jung, M
   Rein, N
   Fuchs, B
AF Jung, M.
   Rein, N.
   Fuchs, B.
TI Physical Therapy for Chemotherapy-induced Peripheral Neuropathy in Pediatric Oncology
SO KLINISCHE PADIATRIE
LA German
DT Article
DE chemotherapy-induced peripheral neuropathy; pediatric oncology; physical therapy; neurologic rehabilitation; systematic review; vinchristin-induced polyneuropathy
ID cancer; children; polyneuropathy; acupuncture; vincristine; performance; management; cipn; life
AB Background: Chemotherapy-induced peripheral neuropathy is a frequent side-effect of drugs that are used in the treatment of cancer. Affected individuals can suffer from motor, sensory or autonomy nerve damage. Further medication is used for the treatment of CIPN which can cause further side-effects. Patients should be offered physical therapy treatment to relieve the symptoms. Objective: The aim of this article is to give an overview of available literature investigating physical therapy in CIPN in pediatric oncology. Methods: To determine relevant literature, a systematic review was conducted in the databases CINAHL, The Cochrane Library, ERIC, MEDPILOT, PEDro, PsycARTICLES, PsycINFO, PubMed and DIMDI. Besides the methodological quality of the identified literature is supposed to be reviewed. Results: There is no current literature regarding the subject of this article, so no evaluation of the quality could be carried out. Although several publications concerning adults could be identified and transfer could be established for pediatrics. Conclusion: Acupuncture appeared to be effective in the treatment of CIPN in adults. Good results appeared especially regarding pain. Sensorimotor training, balance training, electrotherapy and alternative methods like Reiki and Yoga showed good results for patients symptoms. These treatment methods give a future prospect how CIPN in children can be treated successfully - but further pediatric research is necessary.
C1 [Jung, M.; Fuchs, B.] Hsch Fresenius gGmbH, Sch Therapy & Social Work, Marienburgstr 2, D-65510 Idstein, Germany.
   [Rein, N.] Hsch Fresenius gGmbH, Sch Med, Idstein, Germany.
RP Jung, M (corresponding author), Hsch Fresenius gGmbH, Sch Therapy & Social Work, Marienburgstr 2, D-65510 Idstein, Germany.
EM jung.michael@hs-fresenius.de
CR Cavaletti G, 2002, EUR J CANCER, V38, P1832, DOI 10.1016/S0959-8049(02)00229-0
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NR 30
TC 7
Z9 9
U1 1
U2 20
PU GEORG THIEME VERLAG KG
PI STUTTGART
PA RUDIGERSTR 14, D-70469 STUTTGART, GERMANY
SN 0300-8630
EI 1439-3824
J9 KLIN PADIATR
JI Klinische Padiatr.
PD NOV 15
PY 2016
VL 228
IS 6-7
BP 313
EP 318
DI 10.1055/s-0042-111692
PG 6
WC Pediatrics
SC Pediatrics
GA ED1XG
UT WOS:000388637600005
PM 27846661
DA 2026-01-16
ER

PT J
AU Ma, Y
   Dong, M
   Zhou, KH
   Mita, C
   Liu, JP
   Wayne, PM
AF Ma, Yan
   Dong, Ming
   Zhou, Kehua
   Mita, Carol
   Liu, Jianping
   Wayne, Peter M.
TI Publication Trends in Acupuncture Research: A 20-Year Bibliometric Analysis Based on PubMed
SO PLOS ONE
LA English
DT Article
ID low-back-pain; chinese medicine; primary-care; management; quality; metaanalysis; complementary; labor
AB Objective Acupuncture has become popular and widely practiced in many countries around the world. Despite the large amount of acupuncture-related literature that has been published, broader trends in the prevalence and scope of acupuncture research remain underexplored. The current study quantitatively analyzes trends in acupuncture research publications in the past 20 years. Methods A bibliometric approach was used to search PubMed for all acupuncture-related research articles including clinical and animal studies. Inclusion criteria were articles published between 1995 and 2014 with sufficient information for bibliometric analyses. Rates and patterns of acupuncture publication within the 20 year observational period were estimated, and compared with broader publication rates in biomedicine. Identified eligible publications were further analyzed with respect to study type/design, clinical condition addressed, country of origin, and journal impact factor. Results A total of 13,320 acupuncture-related publications were identified using our search strategy and eligibility criteria. Regression analyses indicated an exponential growth in publications over the past two decades, with a mean annual growth rate of 10.7%. This compares to a mean annual growth rate of 4.5% in biomedicine. A striking trend was an observed increase in the proportion of randomized clinical trials (RCTs), from 7.4% in 1995 to 20.3% in 2014, exceeding the 4.5% proportional growth of RCTs in biomedicine. Over the 20 year period, tions). Other top rankings with respect to medical focus were arthritis, neoplasms/cancer, pregnancy or labor, mood disorders, stroke, nausea/vomiting, sleep, and paralysis/palsy. Acupuncture research was conducted in 60 countries, with the top 3 contributors being China (47.4%), United States (17.5%), and United Kingdom (8.2%). Retrieved articles were published mostly in complementary and alternative medicine (CAM) journals with impact factors ranging between 0.7 and 2.8 in the top 20 journals, followed by journals specializing in neuroscience, pain, anesthesia/analgesia, internal medicine and comprehensive fields. Conclusion Acupuncture research has grown markedly in the past two decades, with a 2-fold higher growth rate than for biomedical research overall. Both the increases in the proportion of RCTs and the impact factor of journals support that the quality of published research has improved. While pain was a consistently dominant research focus, other topics gained more attention during this time period. These findings provide a context for analyzing strengths and gaps in the current state of acupuncture research, and for informing a comprehensive strategy for further advancing the field.
C1 [Ma, Yan] PLA, Air Force Gen Hosp, Sleep Ctr, Beijing, Peoples R China.
   [Ma, Yan] Harvard Med Sch, Beth Israel Deaconess Med Ctr, Div Interdisciplinary Med & Biotechnol, Boston, MA 02115 USA.
   [Dong, Ming] IBM Corp, Software Dev Lab, Littleton, MA USA.
   [Zhou, Kehua] Daemen Coll, Dept Hlth Care Studies, Amherst, NY USA.
   [Zhou, Kehua] Daemen Coll, Phys Therapy Wound Care Clin, Amherst, NY USA.
   [Mita, Carol] Harvard Med Sch, Countway Lib Med, Reference & Educ Serv, Boston, MA USA.
   [Liu, Jianping] Beijing Univ Chinese Med, Ctr Evidence Based Chinese Med, Beijing, Peoples R China.
   [Wayne, Peter M.] Brigham & Womens Hosp, Div Prevent Med, Osher Ctr Integrat Med, 75 Francis St, Boston, MA 02115 USA.
   [Wayne, Peter M.] Harvard Med Sch, Boston, MA USA.
C3 Air Force General Hospital PLA; Harvard University; Harvard University Medical Affiliates; Beth Israel Deaconess Medical Center; Harvard Medical School; International Business Machines (IBM); IBM USA; Daemen University; Daemen University; Harvard University; Harvard Medical School; Beijing University of Chinese Medicine; Harvard University; Harvard University Medical Affiliates; Brigham & Women's Hospital; Harvard University; Harvard Medical School
RP Ma, Y (corresponding author), PLA, Air Force Gen Hosp, Sleep Ctr, Beijing, Peoples R China.; Ma, Y (corresponding author), Harvard Med Sch, Beth Israel Deaconess Med Ctr, Div Interdisciplinary Med & Biotechnol, Boston, MA 02115 USA.
EM dr.yan.ma@gmail.com
CR Abaraogu UO, 2015, J ACUPUNCT MERIDIAN, V8, P220, DOI 10.1016/j.jams.2015.06.010
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NR 63
TC 133
Z9 166
U1 5
U2 78
PU PUBLIC LIBRARY SCIENCE
PI SAN FRANCISCO
PA 1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111 USA
SN 1932-6203
EI 
J9 PLOS ONE
JI PLoS One
PD DEC 14
PY 2016
VL 11
IS 12
BP 
EP 
DI 10.1371/journal.pone.0168123
PG 15
WC Multidisciplinary Sciences
SC Science & Technology - Other Topics
GA EI8KC
UT WOS:000392754300056
PM 27973611
DA 2026-01-16
ER

PT J
AU Wang, Y
   Lei, JX
   Gupta, M
   Peng, F
   Lam, S
   Jha, R
   Raduenz, E
   Beitz, AJ
   Gupta, K
AF Wang, Ying
   Lei, Jianxun
   Gupta, Mihir
   Peng, Fei
   Lam, Sarah
   Jha, Ritu
   Raduenz, Ellis
   Beitz, Al J.
   Gupta, Kalpna
TI Electroacupuncture in conscious free-moving mice reduces pain by ameliorating peripheral and central nociceptive mechanisms
SO SCIENTIFIC REPORTS
LA English
DT Article
ID sickle-cell-disease; high-frequency electroacupuncture; opioid receptors; estrous-cycle; substance-p; cancer pain; spinal microglia; beta-endorphin; female rats; acupuncture
AB Integrative approaches such as electroacupuncture, devoid of drug effects are gaining prominence for treating pain. Understanding the mechanisms of electroacupuncture induced analgesia would benefit chronic pain conditions such as sickle cell disease (SCD), for which patients may require opioid analgesics throughout life. Mouse models are instructive in developing a mechanistic understanding of pain, but the anesthesia/restraint required to administer electroacupuncture may alter the underlying mechanisms. To overcome these limitations, we developed a method to perform electroacupuncture in conscious, freely moving, unrestrained mice. Using this technique we demonstrate a significant analgesic effect in transgenic mouse models of SCD and cancer as well as complete Freund's adjuvant-induced pain. We demonstrate a comprehensive antinociceptive effect on mechanical, cold and deep tissue hyperalagesia in both genders. Interestingly, individual mice showed a variable response to electroacupuncture, categorized into high-, moderate-, and non-responders. Mechanistically, electroacupuncture significantly ameliorated inflammatory and nociceptive mediators both peripherally and centrally in sickle mice correlative to the antinociceptive response. Application of sub-optimal doses of morphine in electroacupuncture-treated moderate-responders produced equivalent antinociception as obtained in high-responders. Electroacupuncture in conscious freely moving mice offers an effective approach to develop a mechanism-based understanding of analgesia devoid of the influence of anesthetics or restraints.
C1 [Wang, Ying; Lei, Jianxun; Peng, Fei; Lam, Sarah; Jha, Ritu; Raduenz, Ellis; Gupta, Kalpna] Univ Minnesota, Dept Med, Div Hematol Oncol & Transplantat, Vasc Biol Ctr, 14-100 PWB,516 Delaware ST SE, Minneapolis, MN 55455 USA.
   [Gupta, Mihir] Univ Calif San Diego, Dept Neurosurgery, 200 West Arbor Dr 8893, La Jolla, CA 92103 USA.
   [Beitz, Al J.] Univ Minnesota, Dept Vet & Biomed Sci, 295 Anim Sci Vet Med Bldg,1988 Fitch Ave, St Paul, MN 55108 USA.
C3 University of Minnesota System; University of Minnesota Twin Cities; University of California System; University of California San Diego; University of Minnesota System; University of Minnesota Twin Cities
RP Wang, Y (corresponding author), Univ Minnesota, Dept Med, Div Hematol Oncol & Transplantat, Vasc Biol Ctr, 14-100 PWB,516 Delaware ST SE, Minneapolis, MN 55455 USA.
EM wang5729@umn.edu; gupta014@umn.edu
FU NIH [RO1 103773, UO1 HL117664]; Institute for Engineering in Medicine
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NR 98
TC 15
Z9 17
U1 1
U2 11
PU NATURE PORTFOLIO
PI BERLIN
PA HEIDELBERGER PLATZ 3, BERLIN, 14197, GERMANY
SN 2045-2322
EI 
J9 SCI REP-UK
JI Sci Rep
PD SEP 30
PY 2016
VL 6
IS 
BP 
EP 
DI 10.1038/srep34493
PG 16
WC Multidisciplinary Sciences
SC Science & Technology - Other Topics
GA DX3RW
UT WOS:000384291600001
PM 27687125
DA 2026-01-16
ER

PT J
AU Huang, KY
   Liang, S
   Hu, GY
   Zou, YY
   Lu, L
   Zhang, JB
AF Huang, Kai-yu
   Liang, Shuang
   Hu, Guang-yong
   Zou, Yang-yang
   Lu, Lu
   Zhang, Jian-bin
TI [From Biological Effects of Local Cutaneous Thermal Stimulation to Moxibustion
SO Zhen ci yan jiu = Acupuncture research
LA chi
DT Review
AB Moxibustion is one of the major external therapies of traditional Chinese  medicine (TCM) and exerts a definite favorable effect in the treatment of  patients with different problems. In the present paper, the authors reviewed 38  papers about somatic thermal intervention therapy published in recent 15 years  and analyzed its biological functions from local, distal, and whole body effects.  The local effects include 1) improving cutaneous inflammatory illnesses as  verruca, herpes simplex, Leishmania infection, cutaneous necrosis, wound  disunion, and promoting percutaneous absorption of some medicines, swelling pain;  2) reliving sports fatigue and muscular injury, eliminating inflammation and pain  reactions, probably by lowering local reactive oxygen species, superoxide  dismutase,catalase, glutathione, etc. levels, and strengthening the flexibility  of the knee-joint, and anterior and posterior cruciate ligaments; 3) increasing  blood perfusion of the regional arteriola, micrangium to eliminate accumulated  subcutaneous blood cells, inflammatory mediators and other metabolic products.  The distal effects contain 1) increase of the distal cutaneous blood flow and  suppression of the arterial stenosis; and 2) improvement of the visceral  functions including the heart (ischemia), liver, gastrointestinal blood flow and  smooth muscles, uterus smooth muscular tension, etc. The whole body effects  include raising immunoability against cancer, and reducing tumor blood flow to  damage the blood vessels in the tumor tissue, etc. In addition, the effects of  thermal stimulation are affected by the temperature, stimulating duration and the  stimulated positions. These research results may help us to comprehensively  understand the effects and mechanisms of moxibustion therapy in the treatment of  different clinical disorders.
NR 0
TC 0
SN 
EI 1000-060
J9 Zhen Ci Yan Jiu
PD FEB 19
PY 2016
VL 40
IS 6
BP 504
EP 9
DI 
PG -495
WC Animals; Blood Circulation; Hot Temperature; Humans; Moxibustion; Skin; blood supply; Skin Temperature
UT PubMed:26887216
PM 26887216
DA 2016-02-19
ER

PT J
AU Victorson, D
   Beaumont, JL
   Mahadevan, R
   Grimone, A
   Burns, V
   Murry, W
   Gutierrez, S
   Schuette, S
   Brady, C
   Ring, M
AF Victorson, David
   Beaumont, Jennifer L.
   Mahadevan, Rupa
   Grimone, Ania
   Burns, Virginia
   Murry, Wendy
   Gutierrez, Sandra
   Schuette, Stephanie
   Brady, Caitlin
   Ring, Melinda
TI Acupuncture-Related Quality of Life Changes Using PROMIS Computer Adaptive Tests in a Pragmatic Trial with Oncology and General Integrative Medicine Patients: The Role of Baseline Acupuncture Expectations
SO JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE
LA English
DT Article
DE acupuncture; quality of life; outcomes; pragmatic trial
ID cancer; relief
AB Introduction: Acupuncture has been shown to alleviate symptoms and increase general well-being in different medical patient samples. A major challenge in acupuncture clinical research is the availability of comparable and standardized patient-reported outcome measurement (PRO) tools. Objectives: This study used a pragmatic design to examine longitudinal changes in quality of life (QOL) in a medical patient sample following acupuncture using PROs from the National Institutes of Health's Patient Reported Outcomes Measurement Information System (PROMIS) initiative. It also examined the role of acupuncture expectancies, as well as patient and provider perceptions of acupuncture benefit. Design: Following informed consent, patients completed baseline QOL measures (T1) prior to their first acupuncture session. Subsequent assessments (up to 20) were completed immediately following ensuing acupuncture sessions. Patients completed assessments either on a touch-screen computer at the clinic or from their home computer. Results: Compared with acupuncture-naive participants, those who received prior acupuncture treatment reported significantly higher anxiety, fatigue, sleep disturbance, and lower positive affect at baseline. By the second assessment, however, these differences became nonexistent. Participants who held greater baseline acupuncture expectations (e.g., their situation would improve a lot, they would have improved coping skills, their symptoms would disappear, their energy would increase) reported significantly higher fatigue, pain interference, and problems with physical functioning. Between T1 and T2, all participants reported significant improvements in anxiety, depression, and fatigue. Exploratory longitudinal models demonstrated significant linear improvements over time in anxiety (p=0.006), depression (p=0.007), pain interference (p<0.001), and sleep disturbance (p=0.004). No linear reduction over time was found with fatigue (p=0.587), physical function (p=0.654), or positive affect (p=0.247). Conclusions: Overall, PROMIS computer adaptive tests were able to assess domains of QOL briefly. Although pretreatment acupuncture expectations highlighted subgroup differences in outcomes at baseline, linear-growth models demonstrated the positive effects of acupuncture over time on anxiety, depression, pain interference, and sleep disturbance.
C1 [Victorson, David; Beaumont, Jennifer L.; Gutierrez, Sandra] Northwestern Univ, Dept Med Social Sci, Feinberg Sch Med, 2205 Tech Dr,Hogan Bldg,Suite 2-120, Chicago, IL 60208 USA.
   [Victorson, David; Grimone, Ania; Burns, Virginia; Murry, Wendy; Schuette, Stephanie; Brady, Caitlin; Ring, Melinda] Northwestern Med Grp, Northwestern Med, Osher Ctr Integrat Med, Chicago, IL USA.
   [Mahadevan, Rupa] Advocate Childrens Hosp, Pediat Residency Program, Park Ridge, IL USA.
C3 Northwestern University; Feinberg School of Medicine; Northwestern University; Feinberg School of Medicine
RP Victorson, D (corresponding author), Northwestern Univ, Dept Med Social Sci, Feinberg Sch Med, 2205 Tech Dr,Hogan Bldg,Suite 2-120, Chicago, IL 60208 USA.
EM d-victorson@northwestern.edu
FU Malkin Family Foundation; Osher Center for Integrative Medicine at Northwestern Medicine
CR Brinkhaus B, 2008, ANN ALLERG ASTHMA IM, V101, P535, DOI 10.1016/S1081-1206(10)60294-3
   Cella D, 2010, J CLIN EPIDEMIOL, V63, P1179, DOI 10.1016/j.jclinepi.2010.04.011
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NR 23
TC 8
Z9 9
U1 0
U2 14
PU MARY ANN LIEBERT, INC
PI NEW ROCHELLE
PA 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801 USA
SN 1075-5535
EI 1557-7708
J9 J ALTERN COMPLEM MED
JI J. Altern. Complement Med.
PD OCT 15
PY 2016
VL 22
IS 10
BP 778
EP 787
DI 10.1089/acm.2015.0121
PG 10
WC Integrative & Complementary Medicine
SC Integrative & Complementary Medicine
GA DZ5SU
UT WOS:000385922600004
PM 27467506
DA 2026-01-16
ER

PT J
AU Ma, Y
   Dong, M
   Zhou, K
   Mita, C
   Liu, J
   Wayne, PM
AF Ma, Yan
   Dong, Ming
   Zhou, Kehua
   Mita, Carol
   Liu, Jianping
   Wayne, Peter M
TI Publication Trends in Acupuncture Research: A 20-Year Bibliometric Analysis Based
SO PloS one
LA English
DT Journal Article
AB OBJECTIVE: Acupuncture has become popular and widely practiced in many countries  around the world. Despite the large amount of acupuncture-related literature that  has been published, broader trends in the prevalence and scope of acupuncture  research remain underexplored. The current study quantitatively analyzes trends  in acupuncture research publications in the past 20 years. METHODS: A  bibliometric approach was used to search PubMed for all acupuncture-related  research articles including clinical and animal studies. Inclusion criteria were  articles published between 1995 and 2014 with sufficient information for  bibliometric analyses. Rates and patterns of acupuncture publication within the  20 year observational period were estimated, and compared with broader  publication rates in biomedicine. Identified eligible publications were further  analyzed with respect to study type/design, clinical condition addressed, country  of origin, and journal impact factor. RESULTS: A total of 13,320  acupuncture-related publications were identified using our search strategy and  eligibility criteria. Regression analyses indicated an exponential growth in  publications over the past two decades, with a mean annual growth rate of 10.7%.  This compares to a mean annual growth rate of 4.5% in biomedicine. A striking  trend was an observed increase in the proportion of randomized clinical trials  (RCTs), from 7.4% in 1995 to 20.3% in 2014, exceeding the 4.5% proportional  growth of RCTs in biomedicine. Over the 20 year period, pain was consistently the  most common focus of acupuncture research (37.9% of publications). Other top  rankings with respect to medical focus were arthritis, neoplasms/cancer,  pregnancy or labor, mood disorders, stroke, nausea/vomiting, sleep, and  paralysis/palsy. Acupuncture research was conducted in 60 countries, with the top  3 contributors being China (47.4%), United States (17.5%), and United Kingdom  (8.2%). Retrieved articles were published mostly in complementary and alternative  medicine (CAM) journals with impact factors ranging between 0.7 and 2.8 in the  top 20 journals, followed by journals specializing in neuroscience, pain,  anesthesia/analgesia, internal medicine and comprehensive fields. CONCLUSION:  Acupuncture research has grown markedly in the past two decades, with a 2-fold  higher growth rate than for biomedical research overall. Both the increases in  the proportion of RCTs and the impact factor of journals support that the quality  of published research has improved. While pain was a consistently dominant  research focus, other topics gained more attention during this time period. These  findings provide a context for analyzing strengths and gaps in the current state  of acupuncture research, and for informing a comprehensive strategy for further  advancing the field.
C1 Sleep Center, Air Force General Hospital, PLA, Beijing, China.
   Division of Interdisciplinary Medicine and Biotechnology, Beth Israel Deaconess 
   IBM, Software Development Lab, Littleton, MA, United States of America.
   Department of Health Care Studies & Daemen College Physical Therapy Wound Care Clinic Daemen College, Amherst, NY, United States of America.
   Reference & Education Services, Countway Library of Medicine, Harvard Medical School, Boston, MA, United States of America.
   Center for Evidence-Based Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
   Division of Preventive Medicine, Osher Center for Integrative Medicine, Brigham and Women's Hospital, Boston, MA, United States of America
   Harvard MedicalSchool, Boston, MA, United States of America.
NR 0
TC 0
SN 1932-620
EI 
J9 PLoS One
PD DEC 16
PY 2016
VL 11
IS 12
BP e0168123
EP e0168123
DI 10.1371/journal.pone.0168123
PG 1
WC Acupuncture; Acupuncture Therapy; Animals; Bibliometrics; Biomedical Research; trends; China; Humans; Journal Impact Factor; Prevalence; PubMed; Publications; trends; Randomized Controlled Trials as Topic; Regression Analysis; United Kingdom; United States
UT PubMed:27973611
PM 27973611
DA 2016-12-16
ER

PT J
AU Zhang, M
   Guan, L
AF Zhang, Mengxue
   Guan, Ling
TI [Impact on neutrophil-to-lymphocyte ratio and quality of life in the patients of
SO Zhongguo zhen jiu = Chinese acupuncture & moxibustion
LA chi
DT Journal Article
AB OBJECTIVE: To explore the impact on neutrophil-to-lymphocyte ratio (NLR) and the  quality of life (QOL) in the patients of non-small-cell lung cancer (NSCLC)  treated with wheat-size moxibustion therapy. METHODS: Seventy patients of NSCLC  were randomized into an observation group and a control group, 35 cases in each  one. Finally, 33 cases were participated in the observation group and 32 cases in  the control group for statistical analysis. In the observation group, Zusanli (ST  36) and Feishu (BL 13) were selected for grain-size moxibustion, 9 moxa cones on  each acupoint, once a day. There was the follow-up visit without any treatment  applied in the control group. The trial lasted for 6 weeks. The changes in NLR  and the QOL score before and after treatment were observed in the patients of the  two groups and the differences were compared between the two groups. RESULTS:  Compared with the condition before treatment, in the observation group, NLR was  reduced apparently (P< 0.05), the general health state/life quality field,  physical functioning, emotional functioning, cognitive functioning, fatigue,  pain, short breath, insomnia and anorexia were improved apparently (all P <  0.05). In the control group, the differences were not significant in NLR, the  general health states/life quality field, physical functioning, emotional  functioning, cognitive functioning, role functioning, social functioning,  fatigue, pain, short breath, insomnia and anorexia before and after treatment  (all P > 0.05). In comparison of the two groups, NLR was reduced apparently in  the observation group as compared with that in the control group after treatment  (P < 0.05). The scores of the general health state/life quality field, physical  functioning, emotional functioning and cognitive functioning were increased  apparently as compared with those in the control group after treatment (all P <  0.05). The scores of fatigue, pain, short breath, insomnia and anorexia in the  observation group were reduced apparently as compared with those in the control  group after treatment (all P < 0.05). CONCLUSION: The wheat-size moxibustion  therapy reduces NLR and improves the immune function and quality of life in the  patients of NSCLC.
NR 0
TC 0
SN 
EI 0255-293
J9 Zhongguo Zhen Jiu
PD JUN 29
PY 2016
VL 36
IS 4
BP 342
EP 6
DI 
PG -336
WC Adult; Aged; Carcinoma, Non-Small-Cell Lung; immunology; Female; Humans; Lung Neoplasms; immunology; Lymphocytes; immunology; Male; Middle Aged; Moxibustion; Neutrophils; immunology; Quality of Life
UT PubMed:27352487
PM 27352487
DA 2016-06-29
ER

PT J
AU Argenbright, CA
   Taylor-Piliae, RE
   Loescher, LJ
AF Argenbright, Christine A.
   Taylor-Piliae, Ruth E.
   Loescher, Lois J.
TI Bowenwork for symptom management of women breast cancer survivors with lymphedema: A pilot study
SO COMPLEMENTARY THERAPIES IN CLINICAL PRACTICE
LA English
DT Article
DE Breast neoplasms; Lymphedema; Musculoskeletal manipulations; Complementary
ID quality-of-life; manual lymphatic drainage; alternative medicine; arm lymphedema; therapy; complementary; impact; feasibility; acupuncture; trial
AB Purpose: The objectives of this pilot study for women breast cancer survivors with lymphedema was 1) to evaluate recruitment rates, retention rates, adherence to Bowenwork (a noninvasive complementary therapy involving gentle muscle movements), home exercises, safety and comfort; 2) determine the effect of Bowenwork on quality of life (QOL), functional status, perceived pain, range of motion (ROM), arm/ankle circumference (to assess for localized and systemic changes). Methods: Participants received 4 Bowenwork sessions with home exercises. Initial and post assessments included QOL, functional status, and pain. ROM, arm/ankle circumference and pain measures were recorded before each session. Results: Twenty-one women enrolled in the study; 95% completion; adherence 100%; home exercises 95%; no adverse events. The intervention improved mental health (SF-36-MCS); breast cancer-related functional (FACT-B); increased ROM; reduced arm circumferences. P value set at <0.05. Conclusions: The Bowenwork intervention was safe and acceptable for women breast cancer survivors with lymphedema. (C) 2016 Elsevier Ltd. All rights reserved.
C1 [Argenbright, Christine A.] James Madison Univ, Sch Nursing, Harrisonburg, VA 22807 USA.
   [Taylor-Piliae, Ruth E.; Loescher, Lois J.] Univ Arizona, Coll Nursing, Tucson, AZ 85721 USA.
C3 James Madison University; University of Arizona
RP Argenbright, CA (corresponding author), James Madison Univ, Sch Nursing, Harrisonburg, VA 22807 USA.
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NR 49
TC 4
Z9 6
U1 0
U2 15
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 1744-3881
EI 1873-6947
J9 COMPLEMENT THER CLIN
JI Complement. Ther. Clin. Pract.
PD NOV 15
PY 2016
VL 25
IS 
BP 142
EP 149
DI 10.1016/j.ctcp.2016.09.004
PG 8
WC Integrative & Complementary Medicine
SC Integrative & Complementary Medicine
GA ED8GV
UT WOS:000389110900019
PM 27863604
DA 2026-01-16
ER

PT J
AU Hu, C
   Zhang, H
   Wu, W
   Yu, W
   Li, Y
   Bai, J
   Luo, B
   Li, S
AF Hu, Caiqiong
   Zhang, Haibo
   Wu, Wanyin
   Yu, Weiqing
   Li, Yong
   Bai, Jianping
   Luo, Baohua
   Li, Shuping
TI Acupuncture for Pain Management in Cancer: A Systematic Review and Meta-Analysis.
SO Evidence-based complementary and alternative medicine : eCAM
LA English
DT Review
AB Objective. To evaluate the effectiveness and safety of acupuncture for  cancer-related pain. Methods. A systematic review of literatures published from  database inception to February 2015 was conducted in eight databases. RCTs  involving acupuncture for treatment of cancer-related pain were identified. Two  researchers independently performed article selection, data extraction, and  quality assessment of data. Results. 1,639 participants in twenty RCTs were  analyzed. All selected RCTs were associated with high risk of bias. Meta-analysis  indicated that acupuncture alone did not have superior pain-relieving effects as  compared with conventional drug therapy. However, as compared with the drug  therapy alone, acupuncture plus drug therapy resulted in increased pain remission  rate, shorter onset time of pain relief, longer pain-free duration, and better  quality of life without serious adverse effects. However, GRADE analysis revealed  that the quality of all outcomes about acupuncture plus drug therapy was very  low. Conclusions. Acupuncture plus drug therapy is more effective than  conventional drug therapy alone for cancer-related pain. However, multicenter  high-quality RCTs with larger sample sizes are needed to provide stronger  evidence for the effectiveness of acupuncture in cancer-related pain due to the  low data quality of the studies included in the current meta-analysis.
C1 The Second Clinical Medical School, Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
   Department of Oncology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, China.
   Department of Oncology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, China.
   The Second Clinical Medical School, Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
   Department of Oncology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, China.
   Department of Oncology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, China.
   The Second Clinical Medical School, Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
   The Second Clinical Medical School, Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
NR 0
TC 0
SN 1741-428
EI 1741-427
J9 Evid Based Complement Alternat Med
PD MAR 16
PY 2016
VL 2016
IS 
BP 1720239
EP 1720239
DI 10.1155/2016/1720239
PG 0
UT PubMed:26977172
PM 26977172
DA 2016-03-16
ER

PT J
AU Giron, PS
   Haddad, CAS
   Rizzi, SKLD
   Nazário, ACP
   Facina, G
AF Giron, Patricia Santolia
   Simao Haddad, Cinira Assad
   Lopes de Almeida Rizzi, Samantha Karlla
   Pinto Nazario, Afonso Celso
   Facina, Gil
TI Effectiveness of acupuncture in rehabilitation of physical and functional disorders of women undergoing breast cancer surgery
SO SUPPORTIVE CARE IN CANCER
LA English
DT Article
DE Breast cancer; Rehabilitation; Acupuncture; Depression; Upper limb function
ID lymphedema; shoulder; safety; trial
AB Purpose The purpose of the study is to verify the effectiveness of acupuncture in rehabilitation of physical and functional disorders of women undergoing breast cancer surgery on the following parameters: pain, range of motion, upper limb function, and depressive symptoms. Methods The following are the inclusion criteria: women aged more than 18 years with scapular girdle and upper limb pain after 3 months of surgery and with pain a parts per thousand yen3 in visual analog scale. Patients were divided into two randomized groups which received weekly treatment during 10 sessions. Kinesiotherapy group (G1)-treated with a predefined kinesiotherapy protocol of 30 min. Group Acupuncture + Kinesiotherapy (G2)-treated with the same kinesiotherapy group protocol followed by another 30 min of acupuncture, used in predefined points. Both groups performed physical examination and answered the upper limb function and depressive symptoms questionnaires. Results Forty-eight patients completed the treatment, 24 in each group. Regarding the pain, the two groups had statistically significant improvement in all evaluated moments. In the analysis of depression, it improved significantly only in G1 in the comparison between the first and the tenth session. The upper limb function had improvement in G1 only in the comparison between the first and the tenth session and in G2, in the three evaluation moments. The range of motion (ROM) showed improvement in all evaluated movements. Conclusions There was no difference between groups. Both groups showed statistically significant improvement of the items assessed: pain, depression, upper limb function, and ADM, and there was no difference between them.
C1 [Giron, Patricia Santolia] Rua Marselhesa,249 Vila Mariana, BR-04020060 Sao Paulo, SP, Brazil.
   [Simao Haddad, Cinira Assad; Lopes de Almeida Rizzi, Samantha Karlla; Pinto Nazario, Afonso Celso; Facina, Gil] Univ Fed Sao Paulo, Dept Gynecol, Sao Paulo, Brazil.
C3 Universidade Federal de Sao Paulo (UNIFESP)
RP Giron, PS (corresponding author), Rua Marselhesa,249 Vila Mariana, BR-04020060 Sao Paulo, SP, Brazil.
EM patysantolia@hotmail.com
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NR 25
TC 14
Z9 18
U1 0
U2 32
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0941-4355
EI 1433-7339
J9 SUPPORT CARE CANCER
JI Support. Care Cancer
PD JUN 15
PY 2016
VL 24
IS 6
BP 2491
EP 2496
DI 10.1007/s00520-015-3054-5
PG 6
WC Oncology; Health Care Sciences & Services; Rehabilitation
SC Oncology; Health Care Sciences & Services; Rehabilitation
GA DK5TL
UT WOS:000374983300013
PM 26670916
DA 2026-01-16
ER

PT J
AU Lindblad, K
   Bergkvist, L
   Johansson, AC
AF Lindblad, Katarina
   Bergkvist, Leif
   Johansson, Ann-Christin
TI Evaluation of the treatment of chronic chemotherapy-induced peripheral neuropathy using long-wave diathermy and interferential currents: a randomized controlled trial
SO SUPPORTIVE CARE IN CANCER
LA English
DT Article
DE Physical therapy; Electrotherapy; Diathermy; Interferential current; Cancer
ID test-retest reliability; scrambler therapy; pain; cancer; acupuncture; management; balance; cipn
AB Purpose The purpose was to investigate the effects of long-wave diathermy in combination with interferential currents (interferential therapy and long-wave diathermy at high power (ITH)) in comparison with long-wave diathermy at a power below the active treatment dose (long-wave diathermy at low power (LDL), control group) on sensory and motor symptoms in patients with chronic chemotherapy-induced peripheral neuropathy (CIPN) in the lower extremities. Methods Sixty-seven patients with chronic CIPN were randomized to 12 weeks of either ITH or LDL. Follow-up assessments were performed after the treatment period and at 37 weeks after randomization. The primary outcome was pain (Numeric Rating Scale (NRS)), and the secondary outcomes were discomfort, nerve symptoms, subjective measurement of dizziness (Dizziness Handicap Inventory), and balance. Differences within and between groups were analyzed. Results Pain intensity decreased significantly only in the LDL group directly after the treatment period from NRS median 25 to median 12.5 (P = 0.017). At the 37-week follow-up, no changes were detected, irrespective of group (NRS 13 vs. 20, P = 0.885). Discomfort decreased significantly in both groups at both 12 and 37 weeks after the baseline (P < 0.05). Balance disability showed significant declines in both groups at 12 and 37 weeks (P = 0.001/0.025 in the ITH group vs P = 0.001/<0.001 in the LDL group). Balance ability (tightened Romberg test) increased significantly at both 12 and 37 weeks in both groups (P = 0.004/<0.040 in the ITH group) but did not improve in the LDL group at any of the follow-up time points (P = 0.203 vs P = 0.383). The one-legged stance test was unchanged in the ITH group after 12 weeks but improved 37 weeks after baseline (P = 0.03). No significant changes were observed in the LDL group at any of the follow-up time points. Conclusion This study provides no support for the use of a combination of long-wave diathermy and ITH as a treatment option for patients with chronic CIPN. However, the chronic CIPN symptoms decreased with time irrespective of the treatment.
C1 [Lindblad, Katarina] Vastmanland Cty Hosp, Dept Surg, S-72189 Vasteras, Sweden.
   [Bergkvist, Leif] Uppsala Univ, Vastmanland Cty Hosp, Clin Res Ctr, Dept Surg, S-72189 Vasteras, Sweden.
   [Johansson, Ann-Christin] Malardalen Univ, Clin Res Ctr, Vastmanland Cty Hosp, Dept Physiotherapy,Sch Hlth Care & Social Welf, S-72189 Vasteras, Sweden.
C3 Uppsala University; Malardalen University
RP Lindblad, K (corresponding author), Vastmanland Cty Hosp, Dept Surg, S-72189 Vasteras, Sweden.
EM katarinalindblad@hotmail.com
FU Vastmanland County Hospital, Vasteras, Sweden
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NR 31
TC 13
Z9 16
U1 3
U2 19
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0941-4355
EI 1433-7339
J9 SUPPORT CARE CANCER
JI Support. Care Cancer
PD JUN 15
PY 2016
VL 24
IS 6
BP 2523
EP 2531
DI 10.1007/s00520-015-3060-7
PG 9
WC Oncology; Health Care Sciences & Services; Rehabilitation
SC Oncology; Health Care Sciences & Services; Rehabilitation
GA DK5TL
UT WOS:000374983300017
PM 26687020
DA 2026-01-16
ER

PT J
AU Greenlee, H
   Crew, KD
   Capodice, J
   Awad, D
   Buono, D
   Shi, ZX
   Jeffres, A
   Wyse, S
   Whitman, W
   Trivedi, MS
   Kalinsky, K
   Hershman, DL
AF Greenlee, Heather
   Crew, Katherine D.
   Capodice, Jillian
   Awad, Danielle
   Buono, Donna
   Shi, Zaixing
   Jeffres, Anne
   Wyse, Sharon
   Whitman, Wendy
   Trivedi, Meghna S.
   Kalinsky, Kevin
   Hershman, Dawn L.
TI Randomized sham-controlled pilot trial of weekly electro-acupuncture for the prevention of taxane-induced peripheral neuropathy in women with early stage breast cancer
SO BREAST CANCER RESEARCH AND TREATMENT
LA English
DT Article
DE Acupuncture; Electro-acupuncture; Breast cancer; Chemotherapy-induced peripheral neuropathy; Taxane
ID quality-of-life; weekly paclitaxel; double-blind; high-risk; chemotherapy; acupuncture; management; pain; doxorubicin; oncology
AB To investigate the effect of electro-acupuncture (EA) as a non-pharmacological intervention to prevent or reduce chemotherapy-induced peripheral neuropathy (CIPN) in breast cancer patients undergoing chemotherapy of taxane. Women with stage I-III breast cancer scheduled to receive taxane therapy were randomized to receive a standardized protocol of 12 true or sham EA (SEA) weekly treatments concurrent with taxane treatment. Subjects completed the Brief Pain Inventory-Short Form (BPI-SF), Functional Assessment of Cancer Therapy-Taxane neurotoxicity subscale (FACT-NTX), and other assessments at baseline and weeks 6, 12, and 16. A total of 180 subjects were screened, 63 enrolled and 48 completed week 16 assessments. Mean age was 50 with 25 % white, 25 % black, and 43 % Hispanic; 52 % had no prior chemotherapy. At week 12, both groups reported an increase in mean BPI-SF worst pain score, but no mean differences were found between groups (SEA 2.8 vs. EA 2.6, P = .86). By week 16, the SEA group returned to baseline, while the EA group continued to worsen (SEA 1.7 vs. EA 3.4, P = .03). The increase in BPI-SF worst pain score was 1.62 points higher in the EA group than in the SEA group at week 16 (P = .04). In a randomized, sham-controlled trial of EA for prevention of taxane-induced CIPN, there were no differences in pain or neuropathy between groups at week 12. Of concern, subjects on EA had a slower recovery than SEA subjects. Future studies should focus on EA for treatment as opposed to prevention of CIPN.
C1 [Greenlee, Heather; Crew, Katherine D.; Buono, Donna; Shi, Zaixing; Hershman, Dawn L.] Columbia Univ, Mailman Sch Publ Hlth, 722 W 168th St,Room 733, New York, NY 10032 USA.
   [Greenlee, Heather; Crew, Katherine D.; Awad, Danielle; Jeffres, Anne; Wyse, Sharon; Whitman, Wendy; Kalinsky, Kevin; Hershman, Dawn L.] Columbia Univ, Herbert Irving Comprehens Canc Ctr, 722 W 168th St,Room 733, New York, NY 10032 USA.
   [Crew, Katherine D.; Awad, Danielle; Trivedi, Meghna S.; Kalinsky, Kevin; Hershman, Dawn L.] Columbia Univ, Coll Phys & Surg, 722 W 168th St,Room 733, New York, NY 10032 USA.
   [Capodice, Jillian] Icahn Sch Med Mt Sinai, New York, NY 10029 USA.
   [Greenlee, Heather] Columbia Univ, 722 W 168th St,Room 733, New York, NY 10032 USA.
C3 Columbia University; Columbia University; Columbia University; Icahn School of Medicine at Mount Sinai; Columbia University
RP Greenlee, H (corresponding author), Columbia Univ, Mailman Sch Publ Hlth, 722 W 168th St,Room 733, New York, NY 10032 USA.; Greenlee, H (corresponding author), Columbia Univ, Herbert Irving Comprehens Canc Ctr, 722 W 168th St,Room 733, New York, NY 10032 USA.; Greenlee, H (corresponding author), Columbia Univ, 722 W 168th St,Room 733, New York, NY 10032 USA.
EM hg2120@columbia.edu
FU Breast Cancer Research Foundation; National Cancer Institute NCI [K23CA141052]
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NR 43
TC 95
Z9 110
U1 1
U2 42
PU SPRINGER
PI NEW YORK
PA 233 SPRING ST, NEW YORK, NY 10013 USA
SN 0167-6806
EI 1573-7217
J9 BREAST CANCER RES TR
JI Breast Cancer Res. Treat.
PD APR 15
PY 2016
VL 156
IS 3
BP 453
EP 464
DI 10.1007/s10549-016-3759-2
PG 12
WC Oncology
SC Oncology
GA DK1IU
UT WOS:000374666500006
PM 27013473
DA 2026-01-16
ER

PT J
AU Victorson, D
   Beaumont, JL
   Mahadevan, R
   Grimone, A
   Burns, V
   Murry, W
   Gutierrez, S
   Schuette, S
   Brady, C
   Ring, M
AF Victorson, David
   Beaumont, Jennifer L
   Mahadevan, Rupa
   Grimone, Ania
   Burns, Virginia
   Murry, Wendy
   Gutierrez, Sandra
   Schuette, Stephanie
   Brady, Caitlin
   Ring, Melinda
TI Acupuncture-Related Quality of Life Changes Using PROMIS Computer Adaptive Tests
SO Journal of alternative and complementary medicine (New York, N.Y.)
LA English
DT Journal Article
DE acupuncture; outcomes; pragmatic trial; quality of life
AB INTRODUCTION: Acupuncture has been shown to alleviate symptoms and increase  general well-being in different medical patient samples. A major challenge in  acupuncture clinical research is the availability of comparable and standardized  patient-reported outcome measurement (PRO) tools. OBJECTIVES: This study used a  pragmatic design to examine longitudinal changes in quality of life (QOL) in a  medical patient sample following acupuncture using PROs from the National  Institutes of Health's Patient Reported Outcomes Measurement Information System  (PROMIS) initiative. It also examined the role of acupuncture expectancies, as  well as patient and provider perceptions of acupuncture benefit. DESIGN:  Following informed consent, patients completed baseline QOL measures (T1) prior  to their first acupuncture session. Subsequent assessments (up to 20) were  completed immediately following ensuing acupuncture sessions. Patients completed  assessments either on a touch-screen computer at the clinic or from their home  computer. RESULTS: Compared with acupuncture-naïve participants, those who  received prior acupuncture treatment reported significantly higher anxiety,  fatigue, sleep disturbance, and lower positive affect at baseline. By the second  assessment, however, these differences became nonexistent. Participants who held  greater baseline acupuncture expectations (e.g., their situation would improve a  lot, they would have improved coping skills, their symptoms would disappear,  their energy would increase) reported significantly higher fatigue, pain  interference, and problems with physical functioning. Between T1 and T2, all  participants reported significant improvements in anxiety, depression, and  fatigue. Exploratory longitudinal models demonstrated significant linear  improvements over time in anxiety (p = 0.006), depression (p = 0.007), pain  interference (p < 0.001), and sleep disturbance (p = 0.004). No linear reduction  over time was found with fatigue (p = 0.587), physical function (p = 0.654), or  positive affect (p = 0.247). CONCLUSIONS: Overall, PROMIS computer adaptive tests  were able to assess domains of QOL briefly. Although pretreatment acupuncture  expectations highlighted subgroup differences in outcomes at baseline,  linear-growth models demonstrated the positive effects of acupuncture over time  on anxiety, depression, pain interference, and sleep disturbance.
C1 1 Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine , Chicago, IL.
   2 Osher Center for Integrative Medicine at Northwestern Medicine , Northwestern 
   1 Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine , Chicago, IL.
   3 Pediatric Residency Program, Advocate Children's Hospital , Park Ridge, IL.
   2 Osher Center for Integrative Medicine at Northwestern Medicine , Northwestern Medical Group, Chicago, IL.
   2 Osher Center for Integrative Medicine at Northwestern Medicine , Northwestern Medical Group, Chicago, IL.
   2 Osher Center for Integrative Medicine at Northwestern Medicine , Northwestern Medical Group, Chicago, IL.
   1 Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine , Chicago, IL.
   2 Osher Center for Integrative Medicine at Northwestern Medicine , Northwestern Medical Group, Chicago, IL.
   2 Osher Center for Integrative Medicine at Northwestern Medicine , Northwestern Medical Group, Chicago, IL.
   2 Osher Center for Integrative Medicine at Northwestern Medicine , Northwestern Medical Group, Chicago, IL.
NR 0
TC 0
SN 1557-770
EI 
J9 J Altern Complement Med
PD JUL 29
PY 2016
VL 22
IS 10
BP 778
EP 787
DI 10.1089/acm.2015.0121
PG 9
WC Acupuncture Therapy; psychology; Adult; Aged; Female; Humans; Integrative Medicine; statistics & numerical data; Male; Middle Aged; Patient Satisfaction; statistics & numerical data; Quality of Life; Young Adult
UT PubMed:27467506
PM 27467506
DA 2016-07-29
ER

PT J
AU Sima, L
   Fan, B
   Yan, L
   Shui, Y
AF Sima, Lei
   Fan, Bifa
   Yan, Longtao
   Shui, Yuan
TI Effects of Electroacupuncture Treatment on Bone Cancer Pain Model with Morphine
SO Evidence-based complementary and alternative medicine : eCAM
LA English
DT Journal Article
AB Objective. To explore the efficacy of electroacupuncture treatment in cancer  induced bone pain (CIBP) rat model with morphine tolerance and explore changes of  calcitonin-gene related peptide (CGRP) expression in dorsal root ganglion (DRG).  Methods. Forty SD rats were divided into five groups: sham, CIBP (B), CIBP +  morphine (BM), CIBP + electroacupuncture (BE), and CIBP + morphine +  electroacupuncture (BME). B, BM, BE, and BME groups were prepared CIBP model. The  latter three groups then accepted morphine, electroacupuncture, and morphine  combined electroacupuncture, separately, nine days consecutively (M1 to M9).  Mechanical withdraw threshold (MWT) was evaluated. Results. BE group only had  differences in M1, M2, and M3 compared to B group (P < 0.01). From M5, BM group  showed significantly decreased MWT. Electroacupuncture could obtain analgesic  effects only at early stage (M1 to M5). From M5 to M9, BME had the differences  with BM group (P < 0.01). IOD value of CGRP in BM and BME was substantially less  than in B group. CGRP in BME was significantly lower than that in BM group (P <  0.01). Conclusion. When used in combination with electroacupuncture, morphine  could result in improving analgesic effects and reducing tolerance. CGRP may be  associated with pain behaviors.
C1 National Pain Management and Research Center, China-Japan Friendship Hospital, Beijing, China.
   National Pain Management and Research Center, China-Japan Friendship Hospital, Beijing, China.
   National Pain Management and Research Center, China-Japan Friendship Hospital, Beijing, China.
   National Pain Management and Research Center, China-Japan Friendship Hospital, Beijing, China.
NR 0
TC 0
SN 1741-428
EI 1741-427
J9 Evid Based Complement Alternat Med
PD SEP 28
PY 2016
VL 2016
IS 
BP 8028474
EP 8028474
DI 10.1155/2016/8028474
PG 0
UT PubMed:27672401
PM 27672401
DA 2016-09-28
ER

PT J
AU Majithia, N
   Loprinzi, CL
   Smith, TJ
AF Majithia, Neil
   Loprinzi, Charles L
   Smith, Thomas J
TI New Practical Approaches to Chemotherapy-Induced Neuropathic Pain: Prevention,
SO Oncology (Williston Park, N.Y.)
LA English
DT Review
AB Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most disabling  and demoralizing problems that arise for cancer survivors. When investigating  symptoms of numbness, tingling, or pain in the extremities, it is critical to  determine whether the problem is neuropathic, somatic, or mixed. If the diagnosis  is CIPN, it is important to weigh the potential benefits and harms of possible  treatment options, and to devise an evidence-based multimodality treatment  program. Such programs may include mixtures of opioid and nonopioid adjunctive  medications, based on evidence from CIPN trials, and also extrapolation from  trials in patients with other neuropathic pain syndromes-although such  extrapolating must be done with caution, since other syndromes sometimes respond  to agents that CIPN does not respond to. Other components of a successful program  might include exercise; and possibly neuromodulation via acupuncture, spinal cord  electrical stimulation, or neurocutaneous stimulation. There is good randomized  trial evidence that most of the anticonvulsants and tricyclic antidepressants  typically prescribed for neuropathic pain have little or no effect on CIPN, but  there is some evidence of efficacy for duloxetine-however, clinical practice with  regard to pharmacologic treatment of CIPN often does not reflect these data. We  review here the recommendations of the American Society of Clinical Oncology, as  well as some new and promising approaches to neuropathy, including new  neuromodulation techniques.
NR 0
TC 0
SN 
EI 0890-909
J9 Oncology (Williston Park)
PD NOV 18
PY 2016
VL 30
IS 11
BP 1020
EP 9
DI 
PG -1011
WC Analgesics; therapeutic use; Antineoplastic Agents; adverse effects; Duloxetine Hydrochloride; therapeutic use; Humans; Neuralgia; chemically induced; Pain Management; Peripheral Nervous System Diseases; chemically induced; Randomized Controlled Trials as Topic
UT PubMed:27854104
PM 27854104
DA 2016-11-18
ER

PT J
AU Gjeorgjievski, M
   Manickam, P
   Ghaith, G
   Cappell, MS
AF Gjeorgjievski, Mihajlo
   Manickam, Palaniappan
   Ghaith, Gehad
   Cappell, Mitchell S.
TI Safety and Efficacy of Endoscopic Therapy for Nonmalignant Duodenal Duplication Cysts Case Report and Comprehensive Review of 28 Cases Reported in the Literature
SO MEDICINE
LA English
DT Review
ID acute recurrent pancreatitis; gastrointestinal-tract; management; diagnosis; resection; rare; eus; complications; ultrasound; frequency
AB Analyze efficacy, safety of endoscopic therapy for duodenal duplication cysts (DDC) by comprehensively reviewing case reports. Tandem, independent, systematic, computerized, literature searches were performed via PubMed using medical subject headings or Keywords "cyst" and "duodenal" and "duplication"; or "cyst", and "endoscopy" or "endoscopic", and "therapy" or "decompression"; with reconciliation of generated references by two experts. Case report followed CARE guidelines. Literature review revealed 28 cases (mean = 1.3 +/- 1.2 cases/report). Endoscopic therapy is increasingly reported recently (1984-1999: 3 cases, 2000-2015: 25 cases, P = 0.003, OR = 8.33, 95%-CI: 1.77-44.5). Fourteen (54%) of 26 patients were men (unknown-sex = 2). Mean age = 32.2 +/- 18.3 years old. Procedure indications: acute pancreatitis-16, abdominal pain-8, jaundice-2, gastrointestinal (GI) obstruction-1, asymptomatic cyst-1. Mean maximal DDC dimension = 3.20 +/- 1.53 cm (range, 1-6.5 cm). Endoscopic techniques included cyst puncture via needle knife papillotomy (NKP)/papillotome-18, snare resection of cyst-7, cystotome-2, and cyst needle aspiration/ligation-1. Endoscopic therapy was successful in all cases. Among 24 initially symptomatic patients, all remained asymptomatic post-therapy without relapses (mean follow-up = 36.5 +/- 48.6 months, 3 others reported asymptomatic at follow-up of unknown duration; 1 initially asymptomatic patient remained asymptomatic 3 years post-therapy). Two complications occurred: mild intraprocedural duodenal bleeding related to NKP and treated locally endoscopically. A patient is reported who presented with vomiting, 15-kg-weight-loss, and profound dehydration for 1 month from extrinsic compression of duodenum by 14 x 6 cm DDC, underwent successful endosonographic cyst decompression with large fenestration of cyst and endoscopic aspiration of 1 L of fluid from cyst with rapid relief of symptoms. At endoscopy the DDC was intubated and visualized and random endoscopic mucosal biopsies were obtained to help exclude malignant or dysplastic DDC. Study limitations include retrospective literature review, potential reporting bias, limited patient number, variable follow-up. In conclusion, endoscopic therapy for DDC was efficacious in all 29 reported patients including current case, including patients presenting acutely with acute pancreatitis, or GI obstruction. Complications were rare and minor, suggesting that endoscopic therapy may be a useful alternative to surgery for nonmalignant DDC when performed by expert endoscopists.
C1 [Gjeorgjievski, Mihajlo; Manickam, Palaniappan; Ghaith, Gehad; Cappell, Mitchell S.] William Beaumont Hosp, Div Gastroenterol & Hepatol, MOB 602,3535 West Thirteen Mile Rd, Royal Oak, MI 48073 USA.
   [Ghaith, Gehad; Cappell, Mitchell S.] Oakland Univ, William Beaumont Sch Med, Royal Oak, MI USA.
C3 Beaumont Health; Corewell Health William Beaumont University Hospital; Oakland University
RP Cappell, MS (corresponding author), William Beaumont Hosp, Div Gastroenterol & Hepatol, MOB 602,3535 West Thirteen Mile Rd, Royal Oak, MI 48073 USA.
EM mscappell@yahoo.com
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NR 76
TC 15
Z9 22
U1 0
U2 10
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0025-7974
EI 1536-5964
J9 MEDICINE
JI Medicine (Baltimore)
PD MAY 15
PY 2016
VL 95
IS 22
BP 
EP 
DI 10.1097/MD.0000000000003799
PG 17
WC Medicine, General & Internal
SC General & Internal Medicine
GA DO8QV
UT WOS:000378049400029
PM 27258515
DA 2026-01-16
ER

PT J
AU Tao, WW
   Jiang, H
   Tao, XM
   Jiang, P
   Sha, LY
   Sun, XC
AF Tao, Wei-Wei
   Jiang, Hua
   Tao, Xiao-Mei
   Jiang, Ping
   Sha, Li-Yan
   Sun, Xian-Ce
TI Effects of Acupuncture, Tuina, Tai Chi, Qigong, and Traditional Chinese Medicine Five-Element Music Therapy on Symptom Management and Quality of Life for Cancer Patients: A Meta-Analysis
SO JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
LA English
DT Article
DE Acupuncture; massage; Tai Chi; Qigong; cancer; symptom management; meta-analysis
ID breast-cancer; controlled-trial; postoperative ileus; care; women; electroacupuncture; interventions; survivors; fatigue; moxibustion
AB Context. Most cancer patients suffer from both the disease itself and symptoms induced by conventional treatment. Available literature on the clinical effects on cancer patients of acupuncture, Tuina, Tai Chi, Qigong, and Traditional Chinese Medicine Five-Element Music Therapy (TCM-FEMT) reports controversial results. Objectives. The primary objective of this meta-analysis was to evaluate the effect of acupuncture, Tuina, Tai Chi, Qigong, and TCM-FEMT on various symptoms and quality of life (QOL) in patients with cancer; risk of bias for the selected trials also was assessed. Methods. Studies were identified by searching electronic databases (MEDLINE via both PubMed and Ovid, Cochrane Central, China National Knowledge Infrastructure, Chinese Scientific Journal Database, China Biology Medicine, and Wanfang Database). All randomized controlled trials (RCTs) using acupuncture, Tuina, Tai Chi, Qigong, or TCM-FEMT published before October 2, 2014, were selected, regardless of whether the article was published in Chinese or English. Results. We identified 67 RCTs (5465 patients) that met our inclusion criteria to perform this meta-analysis. Analysis results showed that a significant combined effect was observed for QOL change in patients with terminal cancer in favor of acupuncture and Tuina (Cohen's d: 0.21-4.55, P < 0.05), whereas Tai Chi and Qigong had no effect on QOL of breast cancer survivors (P > 0.05). The meta-analysis also demonstrated that acupuncture produced small-to-large effects on adverse symptoms including pain, fatigue, sleep disturbance, and some gastrointestinal discomfort; however, no significant effect was found on the frequency of hot flashes (Cohen's d = -0.02; 95% CI = -1.49 to 1.45; P = 0.97; I-2 = 36%) and mood distress (P > 0.05). Tuina relieved gastrointestinal discomfort. TCM-FEMT lowered depression level. Tai Chi improved vital capacity of breast cancer patients. High risk of bias was present in 74.63% of the selected RCTs. Major sources of risk of bias were lack of blinding, allocation concealment, and incomplete outcome data. Conclusion. Taken together, although there are some clear limitations regarding the body of research reviewed in this study, a tentative conclusion can be reached that acupuncture, Tuina, Tai Chi, Qigong, or TCM-FEMT represent beneficial adjunctive therapies. Future study reporting in this field should be improved regarding both method and content of interventions and research methods. (c) 2016 American Academy of Hospice and Palliative Medicine. Published by Elsevier Inc. All rights reserved.
C1 [Tao, Wei-Wei; Sha, Li-Yan] Dalian Med Univ, Coll Nursing, 9 West Sect,Lvshun South Rd, Dalian, Peoples R China.
   [Jiang, Ping] Dalian Med Univ, Grad Sch, Dalian, Peoples R China.
   [Sun, Xian-Ce] Dalian Med Univ, Coll Publ Hlth, Dalian, Peoples R China.
   [Jiang, Hua] Peking Univ, Sch Nursing, Beijing 100871, Peoples R China.
   [Tao, Xiao-Mei] Beijing Shijitan Hosp, Beijing, Peoples R China.
C3 Dalian Medical University; Dalian Medical University; Dalian Medical University; Peking University
RP Tao, WW (corresponding author), Dalian Med Univ, Coll Nursing, 9 West Sect,Lvshun South Rd, Dalian, Peoples R China.; Jiang, P (corresponding author), Dalian Med Univ, Grad Sch, Dalian, Peoples R China.
EM taoweiwei2003@163.com; dywx.2009@163.com
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NR 107
TC 160
Z9 194
U1 7
U2 239
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 0885-3924
EI 1873-6513
J9 J PAIN SYMPTOM MANAG
JI J. Pain Symptom Manage.
PD APR 15
PY 2016
VL 51
IS 4
BP 728
EP 747
DI 10.1016/j.jpainsymman.2015.11.027
PG 20
WC Health Care Sciences & Services; Medicine, General & Internal; Clinical Neurology
SC Health Care Sciences & Services; General & Internal Medicine; Neurosciences & Neurology
GA DK1FK
UT WOS:000374657700012
PM 26880252
DA 2026-01-16
ER

PT J
AU Blackburn, H
   West, S
AF Blackburn, Helen
   West, Sandra
TI 1 Management of Postembolization Syndrome Following Hepatic Transarterial Chemoembolization for Primary or Metastatic Liver Cancer
SO CANCER NURSING
LA English
DT Article
DE Fever; Nausea; Pain; Postembolization syndrome; Transarterial chemoembolization
ID transcatheter arterial chemoembolization; irinotecan-eluting beads; quality-of-life; hepatocellular-carcinoma; intraarterial lidocaine; pain; fever; embolization; malignancy; toxicity
AB Background: Transarterial chemoembolization (TACE) is an established treatment in managing liver primary neoplasms or liver metastases. Postembolization syndrome (PES) is a common adverse event defined as fever without associated sepsis, pain in the right upper quadrant, and nausea and/or vomiting. Objective: This integrative review aims to identify effective management strategies for PES or one of its characterizing symptoms (fever, pain, and nausea and/or vomiting). Methods: Searches of electronic databases MEDLINE, EMBASE, and CINAHL were conducted. Fifteen articles were identified for inclusion. Seven addressed all symptoms of PES, and 8 studies focused on individual symptoms of PES. Results: Interventions identified are intra-arterial lidocaine, oral and intravenous analgesics, steroids, wrist-ankle acupuncture, antibiotics, and 5-HT3 receptor antagonists. Findings are explicated according to individual symptoms of PES. Intra-arterial lidocaine, steroids, and a 5-HT3 receptor antagonist are found to offer potential benefit in the management of PES symptoms. Conclusion: A number of interventions have shown potential benefit in the management of PES. A systemic approach using combination therapy is necessary to effectively manage characterizing symptoms. Further research is needed to determine the impact of primary disease site, TACE technique, and chemotherapeutic agent on PES. Implications for Practice: Oncology nurses are uniquely placed to undertake thorough patient assessment after TACE and implement early intervention to effectively manage PES.
C1 [Blackburn, Helen] North Shore Private Hosp, Level 4 North,Westborne St, St Leonards, NSW 2065, Australia.
   [Blackburn, Helen; West, Sandra] Univ Sydney, Sydney Nursing Sch, Sydney, NSW 2006, Australia.
C3 University of Sydney
RP Blackburn, H (corresponding author), North Shore Private Hosp, Level 4 North,Westborne St, St Leonards, NSW 2065, Australia.
EM blackburnh@ramsayhealth.com.au
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NR 34
TC 73
Z9 86
U1 0
U2 51
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0162-220X
EI 1538-9804
J9 CANCER NURS
JI Cancer Nurs.
PD SEP-OCT 15
PY 2016
VL 39
IS 5
BP E1
EP E18
DI 10.1097/NCC.0000000000000302
PG 18
WC Oncology; Nursing
SC Oncology; Nursing
GA DW9LX
UT WOS:000383982600001
PM 26484962
DA 2026-01-16
ER

PT J
AU Wong, YM
AF Wong, Yiu Ming
TI Importance of a Proper Design for Sham Acupuncture Treatment.
SO Journal of acupuncture and meridian studies
LA English
DT Letter
C1 Health Science Unit (PEC), Hong Kong Physically Handicapped & Able Bodied Association, Shamshuipo, Hong Kong.
EM pt@hkphab.org.hk
NR 0
TC 0
SN 2093-815
EI 
J9 J Acupunct Meridian Stud
PD FEB 21
PY 2016
VL 9
IS 1
BP 1,3
EP 1,3
DI 10.1016/j.jams.2015.11.034
PG 1
WC Aromatase Inhibitors; adverse effects; Arthralgia; etiology; Breast Neoplasms; drug therapy; Female; Humans; Multicenter Studies as Topic; standards
UT PubMed:26896069
PM 26896069
DA 2016-02-21
ER

PT J
AU Gruenbaum, SE
   Meng, LZ
   Bilotta, F
AF Gruenbaum, Shaun E.
   Meng, Lingzhong
   Bilotta, Federico
TI Recent trends in the anesthetic management of craniotomy for supratentorial tumor resection
SO CURRENT OPINION IN ANESTHESIOLOGY
LA English
DT Review
DE craniotomy; neuroanesthesia; neurosurgery; supratentorial tumor
ID awake craniotomy; propofol-remifentanil; sevoflurane; recovery; sufentanil
AB Purpose of reviewThe article reviews the recent evidence on the anesthetic management of patients undergoing craniotomy for supratentorial tumor resection.Recent findingsA rapid recovery of neurological function after craniotomy for supratentorial tumor allows for the prompt diagnosis of intracranial complications and possibly an early hospital discharge. Intraoperative esmolol infusion was shown to reduce the anesthetic requirements, and may facilitate a more rapid recovery of neurological function. Outpatient craniotomy for supratentorial tumor resection has been associated with several clinical and economic benefits, but has not gained widespread use because of skepticism and medical-legal concerns. Awake craniotomy is associated with advantageous outcomes compared with surgery under general anesthesia, and is regarded as the standard of care for tumors that reside in or in close proximity to the eloquent brain. Recent studies have demonstrated that intraoperative electroacupuncture, dexmedetomidine, pregabalin, and lidocaine may facilitate postcraniotomy pain management. The use of volatile anesthetic agents in cancer surgery is associated with a worse survival compared with intravenous anesthetics, possibly by hindering immunologic defenses against cancer cells.SummaryRecent evidence has yielded valuable information regarding anesthetic management of patients undergoing supratentorial tumor craniotomy. Despite a plethora of studies that compare short-term outcomes using different anesthetic and analgesic regimens, randomized controlled trials that examine the long-term outcomes (i.e., neurocognitive function, quality of life, tumor recurrence, and survival) that are of particular interest to patients are needed.
C1 [Gruenbaum, Shaun E.; Meng, Lingzhong] Yale Univ, Sch Med, Dept Anesthesiol, New Haven, CT 06510 USA.
   [Bilotta, Federico] Sapienza Univ Rome, Dept Anesthesiol Crit Care & Pain Med, Rome, Italy.
C3 Yale University; Sapienza University Rome
RP Gruenbaum, SE (corresponding author), Yale Univ, Sch Med, Dept Anesthesiol, New Haven, CT 06510 USA.
EM shaun.gruenbaum@yale.edu
FU CTSA from the National Center for Advancing Translational Science, a component of the National Institutes of Health (NIH) [UL1 TR000142]
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NR 30
TC 28
Z9 40
U1 0
U2 22
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0952-7907
EI 1473-6500
J9 CURR OPIN ANESTHESIO
JI Curr. Opin. Anesthesiol.
PD OCT 15
PY 2016
VL 29
IS 5
BP 552
EP 557
DI 10.1097/ACO.0000000000000365
PG 6
WC Anesthesiology
SC Anesthesiology
GA DW9TL
UT WOS:000384005500004
PM 27285727
DA 2026-01-16
ER

PT J
AU Patel, J
   Edelen, C
   Symanowski, J
AF Patel, Jai
   Edelen, Connie
   Symanowski, James
TI Efficacy of Acupuncture (ACU) Therapy for Cancer-Related Pain Management in Oncology Patients (Pts)
SO JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
LA English
DT Meeting Abstract
C1 [Patel, Jai; Symanowski, James] Levine Canc Inst, Charlotte, NC USA.
   [Edelen, Connie] Carolinas Healthcare Syst, Charlotte, NC USA.
C3 Carolinas HealthCare System
NR 0
TC 0
Z9 0
U1 0
U2 8
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
SN 0885-3924
EI 1873-6513
J9 J PAIN SYMPTOM MANAG
JI J. Pain Symptom Manage.
PD FEB 15
PY 2016
VL 51
IS 2
BP 422
EP 423
DI 10.1016/j.jpainsymman.2015.12.032
PG 4
WC Health Care Sciences & Services; Medicine, General & Internal; Clinical Neurology
SC Health Care Sciences & Services; General & Internal Medicine; Neurosciences & Neurology
GA DI4MB
UT WOS:000373472900252
DA 2026-01-16
ER

PT J
AU Kim, W
   Kim, MJ
   Go, D
   Min, BI
   Na, HS
   Kim, SK
AF Kim, Woojin
   Kim, Min Joon
   Go, Donghyun
   Min, Byung-Il
   Na, Heung Sik
   Kim, Sun Kwang
TI Combined Effects of Bee Venom Acupuncture and Morphine on Oxaliplatin-Induced Neuropathic Pain in Mice
SO TOXINS
LA English
DT Article
DE bee venom acupuncture; chemotherapy induced neuropathic pain; morphine; oxaliplatin
ID induced peripheral neuropathy; acupoint stimulation; formalin test; opioid responsiveness; rat model; apipuncture; management; behavior; antinociception; involvement
AB Oxaliplatin, a chemotherapeutic drug for colorectal cancer, induces severe peripheral neuropathy. Bee venom acupuncture (BVA) has been used to attenuate pain, and its effect is known to be mediated by spinal noradrenergic and serotonergic receptors. Morphine is a well-known opioid used to treat different types of pain. Here, we investigated whether treatment with a combination of these two agents has an additive effect on oxaliplatin-induced neuropathic pain in mice. To assess cold and mechanical allodynia, acetone and von Frey filament tests were used, respectively. Significant allodynia signs were observed three days after an oxaliplatin injection (6 mg/kg, i.p.). BVA (0.25, 1, and 2.5 mg/kg, s.c., ST36) or morphine (0.5, 2, and 5 mg/kg, i.p.) alone showed dose-dependent anti-allodynic effects. The combination of BVA and morphine at intermediate doses showed a greater and longer effect than either BVA or morphine alone at the highest dose. Intrathecal pretreatment with the opioidergic (naloxone, 20 g) or 5-HT3 (MDL-72222, 15 g) receptor antagonist, but not with (2)-adrenergic (idazoxan, 10 g) receptor antagonist, blocked this additive effect. Therefore, we suggest that the combination effect of BVA and morphine is mediated by spinal opioidergic and 5-HT3 receptors and this combination has a robust and enduring analgesic action against oxaliplatin-induced neuropathic pain.
C1 [Kim, Woojin; Kim, Sun Kwang] Kyung Hee Univ, Dept Physiol, Coll Korean Med, 26 Kyungheedae Ro, Seoul 02447, South Korea.
   [Kim, Woojin; Kim, Min Joon; Go, Donghyun; Kim, Sun Kwang] Kyung Hee Univ, Grad Sch, Dept East West Med, 26 Kyungheedae Ro, Seoul 02447, South Korea.
   [Min, Byung-Il] Yeongju Municipal Hosp, 697 Jangan Ro, Gyeongsangbuk Do 36051, Yeongju Si, South Korea.
   [Na, Heung Sik] Korea Univ, Dept Physiol, Coll Med, Seoul 02842, South Korea.
C3 Kyung Hee University; Kyung Hee University; Korea University; Korea University Medicine (KU Medicine)
RP Kim, SK (corresponding author), Kyung Hee Univ, Dept Physiol, Coll Korean Med, 26 Kyungheedae Ro, Seoul 02447, South Korea.; Kim, SK (corresponding author), Kyung Hee Univ, Grad Sch, Dept East West Med, 26 Kyungheedae Ro, Seoul 02447, South Korea.
EM thasnow@gmail.com; junesnest@naver.com; drum2r@daum.net; mbi@khu.ac.kr; hsna@korea.ac.kr; skkim77@khu.ac.kr
FU National Research Foundation of Korea (NRF) Grant - Korean Government [NRF-2013R1A1A1012403]
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NR 52
TC 49
Z9 52
U1 1
U2 16
PU MDPI
PI BASEL
PA ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND
SN 2072-6651
EI 
J9 TOXINS
JI Toxins
PD FEB 15
PY 2016
VL 8
IS 2
BP 
EP 
DI 10.3390/toxins8020033
PG 11
WC Food Science & Technology; Toxicology
SC Food Science & Technology; Toxicology
GA DG1MC
UT WOS:000371831200012
PM 26805884
DA 2026-01-16
ER

PT J
AU Suzuki, R
   Small, E
   Makled, M
AF Suzuki, Rie
   Small, Eusebius
   Makled, Melissa
TI Is complementary and alternative medicine use associated with cancer screening rates for women with functional disabilities?
SO COMPLEMENTARY THERAPIES IN MEDICINE
LA English
DT Article
DE Complementary and alternative medicine; Disability; Cancer screenings
ID physical-disability; chronic pain; secondary conditions; health-promotion; adults; breast; mammography; people; barriers; care
AB Objectives: The purpose of this study was to examine the associations of complementary and alternative medicine (CAM) use with mammogram and Pap test rates and functional disabilities (FDs). Design: Cross-sectional study. Setting: Data were derived from the 2012 National Health Interview Survey (n=6576). Analysis: FDs was defined as physical and/or social limitations. The weighted logistic regression models were performed using SAS software. Study covariates were age, race, education, marital status, usual source of care, and insurance. Results: Of 6576 women, a majority were Caucasian (87%), with GED or less (40%), married (50%), having usual source of care (96%) and health insurance (91%), and with FDs (56%). The results indicated that some CAM practices were negatively associated with increased mammogram and Pap test rates while other CAM practices were positively associated. The results indicated that CAM practices that contribute to musculoskeletal problems such as acupuncture and massage were associated with the increased mammogram and Pap test rates. Contrary, women who used chiropractic manipulation, biofeedback, guided imagery, and energy hearing therapy were less likely to obtain cancer screenings regularly regardless of having FDs. Conclusions: The use of several CAM therapies was more likely to be associated with mammogram and Pap test frequency, indicating that the CAM use may be associated with better screening rates due to the improvement of musculoskeletal problems. It is important to determine how each CAM therapy improves secondary health conditions in clinical trials to increase cancer screening rates for women with FDs. (C) 2015 Elsevier Ltd. All rights reserved.
C1 [Suzuki, Rie; Makled, Melissa] Univ Michigan, Sch Hlth Profess & Studies, Flint, MI 48503 USA.
   [Small, Eusebius] Univ Texas Arlington, Sch Social Work, Arlington, TX USA.
C3 University of Michigan System; University of Michigan; University of Michigan Flint; University of Texas System; University of Texas Arlington
RP Suzuki, R (corresponding author), 3124 William S White Bldg,303 E Kearsley St, Flint, MI 48502 USA.
EM rsuzuki@umflint.edu
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NR 55
TC 2
Z9 3
U1 0
U2 5
PU CHURCHILL LIVINGSTONE
PI EDINBURGH
PA JOURNAL PRODUCTION DEPT, ROBERT STEVENSON HOUSE, 1-3 BAXTERS PLACE, LEITH WALK, EDINBURGH EH1 3AF, MIDLOTHIAN, SCOTLAND
SN 0965-2299
EI 1873-6963
J9 COMPLEMENT THER MED
JI Complement. Ther. Med.
PD FEB 15
PY 2016
VL 24
IS 
BP 73
EP 79
DI 10.1016/j.ctim.2015.11.008
PG 7
WC Integrative & Complementary Medicine
SC Integrative & Complementary Medicine
GA DE8NY
UT WOS:000370894100013
PM 26860805
DA 2026-01-16
ER

PT J
AU Hsieh, YL
   Chou, LW
   Hong, SF
   Chang, FC
   Tseng, SW
   Huang, CC
   Yang, CH
   Yang, CC
   Chiu, WF
AF Hsieh, Yueh-Ling
   Chou, Li-Wei
   Hong, Shao-Fu
   Chang, Fei-Chi
   Tseng, Szu-Wen
   Huang, Chi-Chou
   Yang, Ching-Hsiang
   Yang, Chen-Chia
   Chiu, Wei-Feng
TI Laser acupuncture attenuates oxaliplatin-induced peripheral neuropathy in patients with gastrointestinal cancer: a pilot prospective cohort study
SO ACUPUNCTURE IN MEDICINE
LA English
DT Article
DE ONCOLOGY
ID low-level laser; carpal-tunnel syndrome; colorectal-cancer; breast-cancer; management; pain; electroacupuncture; therapy; neurotoxicity; survivors
AB Background Oxaliplatin is a platinum compound that is widely used in the treatment of some solid tumours. Oxaliplatin-induced peripheral neuropathy (OIPN) in the upper and lower extremities is the major adverse side effect and represents the main dose-limiting factor of this drug. The aim of this single-arm study was to evaluate the feasibility and effects of laser acupuncture (LA) in the treatment of OIPN in patients with advanced gastrointestinal cancers. Methods 17 gastrointestinal cancer survivors (14 colorectal and 3 gastric cancers), who had been treated with oxaliplatin-based chemotherapies, were recruited. Low-level laser stimulation (50mW) bilaterally at PC6, PC7, PC8, P9, LU11, SP6, KI3, BL60, KI1, and KI2 was administered for 20min/point for 12 sessions over 4weeks. The pain quality assessment scale (PQAS), chemotherapy-induced neurotoxicity questionnaire (CINQ), oxaliplatin-specific neurotoxicity scale (OSNS), quantitative touch-detection threshold (using von Frey filaments), and cold-triggered pain withdrawal latency (using the cold-water immersion test) were measured before and after completion of the 12 treatment sessions. Results PQAS, CINQ, and OSNS scores, as well as touch-detection threshold and cold-trigger pain withdrawal latency all improved significantly after LA in the cancer patients with OIPN (p<0.05). LA significantly relieved both oxaliplatin-induced cold and mechanical allodynia and also decreased the incidence and severity of neurotoxicity symptoms in the patients' upper and lower extremities and impact on their daily activities (all p<0.05). Conclusions Following treatment with LA, neurotoxicity symptoms were significantly improved in cancer patients with OIPN. Further randomised controlled trials are needed to evaluate the role of LA as a therapeutic option in the management of OIPN.
C1 [Hsieh, Yueh-Ling; Hong, Shao-Fu; Yang, Ching-Hsiang] China Med Univ, Grad Inst Rehabil Sci, Dept Phys Therapy, Taichung, Taiwan.
   [Chou, Li-Wei] China Med Univ, Grad Inst Acupuncture Sci, Coll Chinese Med, Taichung, Taiwan.
   [Chou, Li-Wei] China Med Univ Hosp, Dept Phys Med & Rehabil, Taichung, Taiwan.
   [Hong, Shao-Fu] Chung Shan Med Univ Hosp, Dept Phys Med & Rehabil, Chung Shing Branch, Taichung, Taiwan.
   [Chang, Fei-Chi] Chung Shan Med Univ Hosp, Dept Nursing, Taichung, Taiwan.
   [Tseng, Szu-Wen] Chung Shan Med Univ Hosp, Div Med Oncol, Dept Internal Med, Taichung, Taiwan.
   [Huang, Chi-Chou] Chung Shan Med Univ, Sch Med, Taichung, Taiwan.
   [Huang, Chi-Chou] Chung Shan Med Univ Hosp, Div Colon & Rectum, Dept Surg, Taichung, Taiwan.
   [Yang, Chen-Chia; Chiu, Wei-Feng] Cheng Ching Gen Hosp, Dept Phys Med & Rehabil, Taichung 40407, Taiwan.
C3 China Medical University Taiwan; China Medical University Taiwan; China Medical University Taiwan; China Medical University Hospital - Taiwan; Chung Shan Medical University; Chung Shan Medical University Hospital; Chung Shan Medical University; Chung Shan Medical University Hospital; Chung Shan Medical University; Chung Shan Medical University Hospital; Chung Shan Medical University; Chung Shan Medical University; Chung Shan Medical University Hospital
RP Chiu, WF (corresponding author), Cheng Ching Gen Hosp, Dept Phys Med & Rehabil, Taichung 40407, Taiwan.
EM chengchingchiu@gmail.com; chengchingchiu@gmail.com
FU Ministry of Science and Technology [NSC101-2314-B-039-003-MY2]; Cheng Ching General Hospital in Taiwan [CH10500197]
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   Wong Raimond, 2006, ACUPUNCT MED, V24, P87
   Xu Wei-Ru, 2010, ZHONGGUO ZHEN JIU, V30, P457
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NR 36
TC 37
Z9 40
U1 0
U2 31
PU SAGE PUBLICATIONS LTD
PI LONDON
PA 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND
SN 0964-5284
EI 1759-9873
J9 ACUPUNCT MED
JI Acupunct. Med.
PD OCT 15
PY 2016
VL 34
IS 5
BP 398
EP 405
DI 10.1136/acupmed-2016-011112
PG 8
WC Integrative & Complementary Medicine
SC Integrative & Complementary Medicine
GA EA2WE
UT WOS:000386455700010
PM 27613370
DA 2026-01-16
ER

PT J
AU Kwekkeboom, KL
AF Kwekkeboom, Kristine L.
TI CANCER SYMPTOM CLUSTER MANAGEMENT
SO SEMINARS IN ONCOLOGY NURSING
LA English
DT Article
DE symptom cluster; symptom management; clinical practice; therapeutics; patient education
ID randomized controlled-trial; cognitive-behavioral intervention; quality-of-life; breast-cancer; palliative care; lung-cancer; women; distress; therapy; fatigue
AB OBJECTIVES: To discuss the importance of cancer symptom clusters in clinical practice, review evidence for symptom cluster interventions, and make recommendations for symptom cluster identification, patient education, and management in clinical practice. DATA SOURCES: Primary research and review articles identified through CINAHL, PubMed, and PsycINFO databases. CONCLUSION: Several studies have investigated interventions for multi-symptom management or have evaluated the secondary effects of a single-symptom intervention on related symptoms. To date, only five studies have tested an intervention designed to manage a specific cancer symptom cluster. Those studies used nonpharmacologic approaches (psycho-education, cognitive-behavioral strategies, and acupressure) to address the pain, fatigue, and sleep disturbance symptom cluster, or the respiratory distress symptom cluster with some initial evidence of success. Further development and efficacy testing of symptom cluster interventions is needed. IMPLICATIONS FOR NURSING PRACTICE: Clinical practice can be guided by knowledge of individual and multi-symptom management, and clinical judgment regarding possible etiologies of cancer symptom clusters. Clinicians should be aware of co-occurring symptoms in their patients, educate and involve patients in identifying symptom clusters and aggravating/alleviating factors, and coordinate treatment recommendations using strategies that are likely to be beneficial across symptoms.
C1 [Kwekkeboom, Kristine L.] Univ Wisconsin Madison, Sch Nursing, Signe Skott Cooper Hall,Suite 3137,701 Highland A, Madison, WI 53705 USA.
C3 University of Wisconsin System; University of Wisconsin Madison
RP Kwekkeboom, KL (corresponding author), Univ Wisconsin Madison, Sch Nursing, Signe Skott Cooper Hall,Suite 3137,701 Highland A, Madison, WI 53705 USA.
EM kwekkeboom@wisc.edu
FU National Institute of Nursing Research of the National Institutes of Health [R01NR013468]
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NR 58
TC 132
Z9 151
U1 6
U2 77
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 0749-2081
EI 1878-3449
J9 SEMIN ONCOL NURS
JI Semin. Oncol. Nurs.
PD NOV 15
PY 2016
VL 32
IS 4
BP 373
EP 382
DI 10.1016/j.soncn.2016.08.004
PG 10
WC Oncology; Nursing
SC Oncology; Nursing
GA FR0XU
UT WOS:000418788700005
PM 27789073
DA 2026-01-16
ER

PT J
AU Lahoud, MJ
   Kourie, HR
   Antoun, J
   El, Osta L
   Ghosn, M
AF Lahoud, Marie José
   Kourie, Hampig Raphael
   Antoun, Joelle
   El Osta, Lana
   Ghosn, Marwan
TI Road map for pain management in pancreatic cancer: A review.
SO World journal of gastrointestinal oncology
LA English
DT Review
DE Interventional; Medical; Pain management; Pancreatic cancer; Treatment
AB Beside its poor prognosis and its late diagnosis, pancreatic cancer remains one  of the most painful malignancies. Optimal management of pain in this cancer  represents a real challenge for the oncologist whose objective is to ensure a  better quality of life to his patients. We aimed in this paper to review all the  treatment modalities incriminated in the management of pain in pancreatic cancer  going from painkillers, chemotherapy, radiation therapy and interventional  techniques to agents under investigation and alternative medicine. Although  specific guidelines and recommendations for pain management in pancreatic cancer  are still absent, we present all the possible pain treatments, with a progression  from medical multimodal treatment to radiotherapy and chemotherapy then  interventional techniques in case of resistance. In addition, alternative methods  such as acupuncture and hypnosis can be added at any stage and seems to  contribute to pain relief.
C1 Marie José Lahoud, Department of Anesthesiology and Critical Care, Faculty of Medicine, Saint Joseph University, Beirut 166830, Lebanon.
   Marie José Lahoud, Department of Anesthesiology and Critical Care, Faculty of Medicine, Saint Joseph University, Beirut 166830, Lebanon.
   Marie José Lahoud, Department of Anesthesiology and Critical Care, Faculty of Medicine, Saint Joseph University, Beirut 166830, Lebanon.
   Marie José Lahoud, Department of Anesthesiology and Critical Care, Faculty of Medicine, Saint Joseph University, Beirut 166830, Lebanon.
   Marie José Lahoud, Department of Anesthesiology and Critical Care, Faculty of Medicine, Saint Joseph University, Beirut 166830, Lebanon.
NR 0
TC 0
SN 1948-520
EI 1948-520
J9 World J Gastrointest Oncol
PD AUG 31
PY 2016
VL 8
IS 8
BP 599
EP 606
DI 10.4251/wjgo.v8.i8.599
PG 7
UT PubMed:27574552
PM 27574552
DA 2016-08-31
ER

PT J
AU Chiu, HY
   Hsieh, YJ
   Tsai, PS
AF Chiu, H Y
   Hsieh, Y J
   Tsai, P S
TI Systematic review and meta-analysis of acupuncture to reduce cancer-related pain.
SO European journal of cancer care
LA English
DT Journal Article
DE acupuncture; cancer-related pain; meta-analysis
AB We conducted a systematic review and meta-analysis to evaluate the effects of  acupuncture on malignancy-related, chemotherapy (CT)- or radiation therapy  (RT)-induced, surgery-induced, and hormone therapy (HT)-induced pain. Randomised  controlled trials (RCTs) examining the effects of acupuncture on cancer-related  pain were reached from the EMBASE, PubMed, PsycINFO, Cochrane Central Register of  Controlled Trials, CINAHL, Airiti library, Taiwan Electrical Periodical Service,  Wanfang Data (a Chinese database) and China Knowledge Resource Integrated  Database from inception through June 2014. Heterogeneity, moderator analysis,  publication bias and risk of bias associated with the included studies were  examined. A total of 29 RCTs yielding 36 effect sizes were included. The overall  effect of acupuncture on cancer-related pain was -0.45 [95% confidence interval  (CI) = -0.63 to -0.26]. The subanalysis indicated that acupuncture relieved  malignancy-related and surgery-induced pain [effect size (g) = -0.71, and -0.40;  95% CI = -0.94 to -0.48, and -0.69 to -0.10] but not CT- or RT-induced and  HT-induced pain (g = -0.05, and -0.64, 95% CI = -0.33 to 0.24, and -1.55 to  0.27). Acupuncture is effective in relieving cancer-related pain, particularly  malignancy-related and surgery-induced pain. Our findings suggest that  acupuncture can be adopted as part of a multimodal approach for reducing  cancer-related pain.
C1 School of Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan.
   School of Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan.
   School of Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan.
NR 0
TC 0
SN 1365-235
EI 
J9 Eur J Cancer Care (Engl)
PD FEB 9
PY 2016
VL 26
IS 2
BP 
EP 
DI 10.1111/ecc.12457
PG 0
WC Acupuncture Therapy; methods; Cancer Pain; therapy; Humans
UT PubMed:26853524
PM 26853524
DA 2016-02-09
ER

PT J
AU Mukherji, A
   Glickman-Simon, R
AF Mukherji, Atreyi
   Glickman-Simon, Richard
TI MINDFULNESS-BASED STRESS REDUCTION FOR POSTTRAUMATIC STRESS DISORDER, COFFEE CONSUMPTION AND MORTALITY, PHYTOESTROGENS FOR MENOPAUSE, LIGHT THERAPY FOR NON-SEASONAL DEPRESSION, ELECTROACUPUNCTURE FOR LABOR PAIN
SO EXPLORE-THE JOURNAL OF SCIENCE AND HEALING
LA English
DT Editorial Material
ID cardiovascular-disease; caffeine intake; mood disorders; risk; symptoms; efficacy; metaanalysis; cancer; meditation; carcinoma
C1 [Mukherji, Atreyi] McMaster Univ, Internal Med & Infect Dis, Hamilton, ON L8S 4L8, Canada.
   [Mukherji, Atreyi] McMaster Univ, Integrat Med, Hamilton, ON L8S 4L8, Canada.
   [Mukherji, Atreyi] McMaster Univ, Hamilton, ON L8S 4L8, Canada.
   [Glickman-Simon, Richard] Tufts Univ, Sch Med, Publ Hlth & Family Med, Boston, MA 02111 USA.
   [Glickman-Simon, Richard] DynaMed, Ipswich, MA USA.
C3 McMaster University; McMaster University; McMaster University; Tufts University
RP Mukherji, A (corresponding author), McMaster Univ, Internal Med & Infect Dis, Hamilton, ON L8S 4L8, Canada.; Mukherji, A (corresponding author), McMaster Univ, Integrat Med, Hamilton, ON L8S 4L8, Canada.; Mukherji, A (corresponding author), McMaster Univ, Hamilton, ON L8S 4L8, Canada.
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NR 45
TC 0
Z9 0
U1 0
U2 21
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 1550-8307
EI 1878-7541
J9 EXPLORE-NY
JI Explore-J Sci. Heal.
PD MAY-JUN 15
PY 2016
VL 12
IS 3
BP 210
EP 214
DI 10.1016/j.explore.2016.02.013
PG 5
WC Integrative & Complementary Medicine
SC Integrative & Complementary Medicine
GA DL7MN
UT WOS:000375824900012
PM 27061036
DA 2026-01-16
ER

PT J
AU Wang, Y
   Lei, J
   Gupta, M
   Peng, F
   Lam, S
   Jha, R
   Raduenz, E
   Beitz, AJ
   Gupta, K
AF Wang, Ying
   Lei, Jianxun
   Gupta, Mihir
   Peng, Fei
   Lam, Sarah
   Jha, Ritu
   Raduenz, Ellis
   Beitz, Al J
   Gupta, Kalpna
TI Electroacupuncture in conscious free-moving mice reduces pain by ameliorating
SO Scientific reports
LA English
DT Journal Article
AB Integrative approaches such as electroacupuncture, devoid of drug effects are  gaining prominence for treating pain. Understanding the mechanisms of  electroacupuncture induced analgesia would benefit chronic pain conditions such  as sickle cell disease (SCD), for which patients may require opioid analgesics  throughout life. Mouse models are instructive in developing a mechanistic  understanding of pain, but the anesthesia/restraint required to administer  electroacupuncture may alter the underlying mechanisms. To overcome these  limitations, we developed a method to perform electroacupuncture in conscious,  freely moving, unrestrained mice. Using this technique we demonstrate a  significant analgesic effect in transgenic mouse models of SCD and cancer as well  as complete Freund's adjuvant-induced pain. We demonstrate a comprehensive  antinociceptive effect on mechanical, cold and deep tissue hyperalagesia in both  genders. Interestingly, individual mice showed a variable response to  electroacupuncture, categorized into high-, moderate-, and non-responders.  Mechanistically, electroacupuncture significantly ameliorated inflammatory and  nociceptive mediators both peripherally and centrally in sickle mice correlative  to the antinociceptive response. Application of sub-optimal doses of morphine in  electroacupuncture-treated moderate-responders produced equivalent  antinociception as obtained in high-responders. Electroacupuncture in conscious  freely moving mice offers an effective approach to develop a mechanism-based  understanding of analgesia devoid of the influence of anesthetics or restraints.
C1 Vascular Biology Center, Division of Hematology, Oncology &Transplantation, Department of Medicine, University of Minnesota, 14-100 PWB, 516 Delaware ST SE,Minneapolis, MN 55455, USA.
   Vascular Biology Center, Division of Hematology, Oncology &Transplantation, Department of Medicine, University of Minnesota, 14-100 PWB, 516 Delaware ST SE,Minneapolis, MN 55455, USA.
   Department of Neurosurgery, University of California San Diego, 200 West Arbor Drive #8893, La Jolla, CA 92103-8893, USA.
   Vascular Biology Center, Division of Hematology, Oncology &Transplantation, Department of Medicine, University of Minnesota, 14-100 PWB, 516 Delaware ST SE,Minneapolis, MN 55455, USA.
   Vascular Biology Center, Division of Hematology, Oncology &Transplantation, Department of Medicine, University of Minnesota, 14-100 PWB, 516 Delaware ST SE,Minneapolis, MN 55455, USA.
   Vascular Biology Center, Division of Hematology, Oncology &Transplantation, Department of Medicine, University of Minnesota, 14-100 PWB, 516 Delaware ST SE,Minneapolis, MN 55455, USA.
   Vascular Biology Center, Division of Hematology, Oncology &Transplantation, Department of Medicine, University of Minnesota, 14-100 PWB, 516 Delaware ST SE,Minneapolis, MN 55455, USA.
   Department of Veterinary and Biomedical Sciences, University of Minnesota, 295 Animal Science/Veterinary Medicine Bldg, 1988 Fitch Ave, St. Paul, MN 55108, USA.
   Vascular Biology Center, Division of Hematology, Oncology &Transplantation, Department of Medicine, University of Minnesota, 14-100 PWB, 516 Delaware ST SE,Minneapolis, MN 55455, USA.
NR 0
TC 0
SN 2045-232
EI 
J9 Sci Rep
PD OCT 1
PY 2016
VL 6
IS 
BP 34493
EP 34493
DI 10.1038/srep34493
PG 0
UT PubMed:27687125
PM 27687125
DA 2016-10-01
ER

PT J
AU Viel, E
   Vanoli, A
   Melis, A
   Rocher, F
   Schipman, B
   Truong, D
AF Viel, E.
   Vanoli, A.
   Melis, A.
   Rocher, F.
   Schipman, B.
   Truong, D.
TI Efficiency of auricular acupuncture in climacteric symptoms after cancer treatments
SO CLIMACTERIC
LA English
DT Article
DE Auricular acupuncture; auriculotherapy; hot flushes; cancer
ID women; pain
AB Objectives: This paper aims to highlight the efficiency of auriculotherapy in the treatment of hot flushes, especially in cancer-related menopausal transition.Methods: We used systematically collected data from patients in 2014 in a medical oncology practice. The treatment was made according to the guidelines of The Inter-University Diploma and the cartography of the World Health Organization; data on satisfaction were collected orally.Results: In 2014, 49 patients, among whom 41 had cancer, were treated for hot flushes. Although it is not recommended to treat several symptoms during the same session, we dealt with 1.7 symptoms per session on average. Sixty-nine percent of the patients were satisfied. We lacked data for nine patients, who did not come to the minimal recommended number of treatments (three). Only one patient among those who did not observe any improvement received three treatments.Conclusions: Auricular acupuncture is a safe and cheap method to treat hot flushes. It has been effective in numerous and various cases, among which were patients who presented cancer-related menopausal symptoms. It may be applied for a large variety of other symptoms.
C1 [Rocher, F.; Schipman, B.] Oncol & Radiotherapy Ctr Du Parc, Chalon Sur Saone, France.
RP Viel, E (corresponding author), 4 Allees St Jean des Vignes, F-71100 Chalon Sur Saone, France.
EM viel.erika@orange.fr
CR Alimi D, 2000, J PAIN SYMPTOM MANAG, V19, P81, DOI 10.1016/S0885-3924(99)00140-2
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NR 13
TC 3
Z9 4
U1 0
U2 14
PU TAYLOR & FRANCIS LTD
PI ABINGDON
PA 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXON, ENGLAND
SN 1369-7137
EI 1473-0804
J9 CLIMACTERIC
JI Climacteric
PD JUN 15
PY 2016
VL 19
IS 3
BP 274
EP 278
DI 10.3109/13697137.2016.1164135
PG 5
WC Obstetrics & Gynecology
SC Obstetrics & Gynecology
GA DL8CF
UT WOS:000375866300013
PM 27102586
DA 2026-01-16
ER

PT J
AU Quinlan-Woodward, J
   Gode, A
   Dusek, JA
   Reinstein, AS
   Johnson, JR
   Sendelbach, S
AF Quinlan-Woodward, Jessica
   Gode, Autumn
   Dusek, Jeffery A.
   Reinstein, Adam S.
   Johnson, Jill R.
   Sendelbach, Sue
TI Assessing the Impact of Acupuncture on Pain, Nausea, Anxiety, and Coping in Women Undergoing a Mastectomy
SO ONCOLOGY NURSING FORUM
LA English
DT Article
DE anxiety; pain; nausea/vomiting; breast cancer; acupuncture
ID acute postoperative pain; integrative medicine; cancer-patients; breast-cancer; management; mechanisms; inpatients; surgery; adults; care
AB Purpose/Objectives: To compare the effect of acupuncture to a standard-of-care (control) group on pain, nausea, anxiety, and ability to cope. Design: Pilot randomized, controlled trial. Setting: Abbott Northwestern Hospital, a large, urban, tertiary care hospital in Minneapolis, Minnesota. Sample: 30 adult women undergoing surgery for breast cancer. Methods: Women were randomly assigned to two hospital-based acupuncture treatments versus usual care after breast cancer surgery. Pain, nausea, anxiety, and the patient's ability to cope pre-and post-treatment were compared within and between groups at two different time points postoperatively. Main Research Variables: Mean change in pain, nausea, anxiety, and ability to cope by treatment group. Findings: Compared to women assigned to the control group, women who received acupuncture reported a statistically significant greater reduction in pain, nausea, anxiety, and increase in ability to cope on the first postoperative day and in pain on the second postoperative day following mastectomy surgery. Conclusions: Acupuncture delivered postoperatively in the hospital after mastectomy can reduce the severity of symptoms experienced, as well as increase the patient's ability to cope with her symptoms. However, before implementation as a standard of care, further research needs to be conducted. Implications for Nursing: Acupuncture adds a nonpharmacologic intervention for symptom management in women undergoing mastectomies for breast cancer.
C1 [Quinlan-Woodward, Jessica; Gode, Autumn; Reinstein, Adam S.; Johnson, Jill R.] Abbott NW Hosp, Penny George Inst Hlth & Healing, Minneapolis, MN 55407 USA.
   [Dusek, Jeffery A.] Abbott NW Hosp, Penny George Inst Hlth & Healing, Res, Minneapolis, MN USA.
   [Sendelbach, Sue] Abbott NW Hosp, Nursing Res, Minneapolis, MN USA.
RP Quinlan-Woodward, J (corresponding author), Abbott NW Hosp, Penny George Inst Hlth & Healing, Minneapolis, MN 55407 USA.
EM jessica.quinlan@allina.com
CR Unknown -, 2015, NCCN CLINICAL PRACTICE GUIDELINES IN ONCOLOGY: PROSTATE CANCER, V0, P0
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   Tada H, 2003, DIGEST DIS SCI, V48, P59, DOI 10.1023/A:1021730314068
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NR 30
TC 40
Z9 46
U1 0
U2 41
PU ONCOLOGY NURSING SOC
PI PITTSBURGH
PA 125 ENTERPRISE DR, PITTSBURGH, PA 15275 USA
SN 0190-535X
EI 1538-0688
J9 ONCOL NURS FORUM
JI Oncol. Nurs. Forum
PD NOV 15
PY 2016
VL 43
IS 6
BP 725
EP 732
DI 10.1188/16.ONF.725-732
PG 8
WC Oncology; Nursing
SC Oncology; Nursing
GA EA1EY
UT WOS:000386336500013
PM 27768139
DA 2026-01-16
ER

PT J
AU Jung, M
   Rein, N
   Fuchs, B
AF Jung, M
   Rein, N
   Fuchs, B
TI [Physical Therapy for Chemotherapy-induced Peripheral Neuropathy in Pediatric
SO Klinische Padiatrie
LA ger
DT Journal Article
AB Background: Chemotherapy-induced peripheral neuropathy is a frequent side-effect  of drugs that are used in the treatment of cancer. Affected individuals can  suffer from motor, sensory or autonomy nerve damage. Further medication is used  for the treatment of CIPN which can cause further side-effects. Patients should  be offered physical therapy treatment to relieve the symptoms. Objective: The aim  of this article is to give an overview of available literature investigating  physical therapy in CIPN in pediatric oncology. Methods: To determine relevant  literature, a systematic review was conducted in the databases CINAHL, The  Cochrane Library, ERIC, MEDPILOT, PEDro, PsycARTICLES, PsycINFO, PubMed and  DIMDI. Besides the methodological quality of the identified literature is  supposed to be reviewed. Results: There is no current literature regarding the  subject of this article, so no evaluation of the quality could be carried out.  Although several publications concerning adults could be identified and transfer  could be established for pediatrics. Conclusion: Acupuncture appeared to be  effective in the treatment of CIPN in adults. Good results appeared especially  regarding pain. Sensorimotor training, balance training, electrotherapy and  alternative methods like Reiki and Yoga showed good results for patients  symptoms. These treatment methods give a future prospect how CIPN in children can  be treated successfully - but further pediatric research is necessary.
C1 School of Therapy and Social Works, Hochschule Fresenius gGmbH, Idstein.
   Medical School, Hochschule Fresenius gGmbH, Idstein.
   School of Therapy and Social Works, Hochschule Fresenius gGmbH, Idstein.
NR 0
TC 0
SN 1439-382
EI 
J9 Klin Padiatr
PD NOV 16
PY 2016
VL 228
IS 6-07
BP 313
EP 318
DI 10.1055/s-0042-111692
PG 5
WC Acupuncture Therapy; Antineoplastic Agents; adverse effects; Child; Humans; Neoplasms; drug therapy; Peripheral Nervous System Diseases; chemically induced; Physical Therapy Modalities; Treatment Outcome
UT PubMed:27846661
PM 27846661
DA 2016-11-16
ER

PT J
AU Majithia, N
   Loprinzi, CL
   Smith, TJ
AF Majithia, Neil
   Loprinzi, Charles L.
   Smith, Thomas J.
TI New Practical Approaches to Chemotherapy-Induced Neuropathic Pain: Prevention, Assessment, and Treatment
SO ONCOLOGY-NEW YORK
LA English
DT Article
ID induced peripheral neuropathy; oxaliplatin-induced neuropathy; placebo-controlled trial; acetyl-l-carnitine; quality-of-life; ovarian-cancer patients; randomized phase-ii; cisplatin-induced toxicity; cell lung-cancer; double-blind
AB Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most disabling and demoralizing problems that arise for cancer survivors. When investigating symptoms of numbness, tingling, or pain in the extremities, it is critical to determine whether the problem is neuropathic, somatic, or mixed. If the diagnosis is CIPN, it is important to weigh the potential benefits and harms of possible treatment options, and to devise an evidence-based multimodality treatment program. Such programs may include mixtures of opioid and nonopioid adjunctive medications, based on evidence from CIPN trials, and also extrapolation from trials in patients with other neuropathic pain syndromes-although such extrapolating must be done with caution, since other syndromes sometimes respond to agents that CIPN does not respond to. Other components of a successful program might include exercise; and possibly neuromodulation via acupuncture, spinal cord electrical stimulation, or neurocutaneous stimulation. There is good randomized trial evidence that most of the anticonvulsants and tricyclic antidepressants typically prescribed for neuropathic pain have little or no effect on CIPN, but there is some evidence of efficacy for duloxetine-however, clinical practice with regard to pharmacologic treatment of CIPN often does not reflect these data. We review here the recommendations of the American Society of Clinical Oncology, as well as some new and promising approaches to neuropathy, including new neuromodulation techniques.
C1 [Majithia, Neil; Loprinzi, Charles L.] Mayo Clin, Rochester, MN 55905 USA.
   [Smith, Thomas J.] Johns Hopkins Univ, Sidney Kimmel Comprehens Canc Ctr, Baltimore, MD USA.
C3 Mayo Clinic; Johns Hopkins University; Johns Hopkins Medicine
RP Majithia, N (corresponding author), Mayo Clin, Rochester, MN 55905 USA.
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NR 91
TC 52
Z9 58
U1 1
U2 18
PU UBM MEDICA
PI NORWALK
PA 535 CONNECTICUT AVE, STE 300, NORWALK, CT 06854 USA
SN 0890-9091
EI 
J9 ONCOLOGY-NY
JI Oncology-NY
PD NOV 15
PY 2016
VL 30
IS 11
BP 1020
EP 1029
DI 
PG 10
WC Oncology
SC Oncology
GA EI0WC
UT WOS:000392194900011
PM 27854104
DA 2026-01-16
ER

PT J
AU Kilian-Kita, A
   Puskulluoglu, M
   Konopka, K
   Krzemieniecki, K
AF Kilian-Kita, Aneta
   Puskulluoglu, Mirosława
   Konopka, Kamil
   Krzemieniecki, Krzysztof
TI Acupuncture: could it become everyday practice in oncology?
SO Contemporary oncology (Poznan, Poland)
LA English
DT Review
DE acupuncture; cancer; complementary and alternative treatment; side effects; supportive treatment
AB Acupuncture is a complementary and alternative medical treatment (CAM) which is  increasingly used in the care of cancer patients. Traditionally derived from  Chinese medicine, nowadays it is becoming a part of evidence-based oncology. The  use of acupuncture in these patients has been recommended by the American Cancer  Society (ACS) for the treatment of side effects associated with conventional  cancer therapy and cancer-related ailments. A growing body of evidence supports  the use of acupuncture in the treatment of cancer-induced pain and  chemotherapy-related nausea and vomiting. Also other indications, such as  xerostomia, fatigue, hot flashes, anxiety and peripheral neuropathy, are being  constantly evaluated. This article summarizes the most important discoveries  related to the possible usefulness of this method in contemporary oncology.  Emphasis is placed on the results of randomized controlled trials with an  adequate level of evidence. However, explanation of the mechanisms responsible  for these effects requires confirmation in further studies with an adequate level  of evidence. In future, acupuncture may become an interesting and valuable  addition to conventional medicine.
C1 Department of Clinical Oncology, University Hospital in Krakow, Krakow, Poland.
   Department of Clinical Oncology, University Hospital in Krakow, Krakow, Poland.
   Department of Clinical Oncology, University Hospital in Krakow, Krakow, Poland.
   Department of Clinical Oncology, University Hospital in Krakow, Krakow, Poland.
NR 0
TC 0
SN 1897-430
EI 1428-252
J9 Contemp Oncol (Pozn)
PD JUL 1
PY 2016
VL 20
IS 2
BP 119
EP 23
DI 10.5114/wo.2016.60065
PG -96
UT PubMed:27358589
PM 27358589
DA 2016-07-01
ER

PT J
AU Lau, CHY
   Wu, X
   Chung, VCH
   Liu, X
   Hui, EP
   Cramer, H
   Lauche, R
   Wong, SYS
   Lau, AYL
   Sit, RWS
   Ziea, ETC
   Ng, BFL
   Wu, JCY
AF Lau, Charlotte H Y
   Wu, Xinyin
   Chung, Vincent C H
   Liu, Xin
   Hui, Edwin P
   Cramer, Holger
   Lauche, Romy
   Wong, Samuel Y S
   Lau, Alexander Y L
   Sit, Regina W S
   Ziea, Eric T C
   Ng, Bacon F L
   Wu, Justin C Y
TI Acupuncture and Related Therapies for Symptom Management in Palliative Cancer
SO Medicine
LA English
DT Journal Article
AB Available systematic reviews showed uncertainty on the effectiveness of using  acupuncture and related therapies for palliative cancer care. The aim of this  systematic review and meta-analysis was to summarize current best evidence on  acupuncture and related therapies for palliative cancer care. Five international  and 3 Chinese databases were searched. Randomized controlled trials (RCTs)  comparing acupuncture and related therapies with conventional or sham treatments  were considered. Primary outcomes included fatigue, paresthesia and dysesthesias,  chronic pain, anorexia, insomnia, limb edema, constipation, and health-related  quality of life, of which effective conventional interventions are limited.  Thirteen RCTs were included. Compared with conventional interventions,  meta-analysis demonstrated that acupuncture and related therapies significantly  reduced pain (2 studies, n = 175, pooled weighted mean difference: -0.76, 95%  confidence interval: -0.14 to -0.39) among patients with liver or gastric cancer.  Combined use of acupuncture and related therapies and Chinese herbal medicine  improved quality of life in patients with gastrointestinal cancer (2 studies,  n = 111, pooled standard mean difference: 0.75, 95% confidence interval:  0.36-1.13). Acupressure showed significant efficacy in reducing fatigue in lung  cancer patients when compared with sham acupressure. Adverse events for  acupuncture and related therapies were infrequent and mild. Acupuncture and  related therapies are effective in reducing pain, fatigue, and in improving  quality of life when compared with conventional intervention alone among cancer  patients. Limitations on current evidence body imply that they should be used as  a complement, rather than an alternative, to conventional care. Effectiveness of  acupuncture and related therapies for managing anorexia, reducing constipation,  paresthesia and dysesthesia, insomnia, and limb edema in cancer patients is  uncertain, warranting future RCTs in these areas.
C1 From the Faculty of Medicine (CHL)
   Hong Kong Institute of Integrative Medicine (XW, VCC, EPH, SYW, AYL, RWSS, JCW)
   Jockey Club School of Public Health andPrimary Care (XW, VCC, XL, SYW, RWSS)
   Comprehensive Cancer Trials Unit (EPH),The Chinese University of Hong Kong, Hong Kong, China
   Department of Internal andIntegrative Medicine (HC), Faculty of Medicine, Kliniken Essen-MitteUniversity ofDuisburg-Essen, Essen, Germany
   Australian Research Centre in Complementary andIntegrative Medicine (ARCCIM) (HC), Faculty of Health, University of TechnologySydney, Sydney, Australia
   Department of Medicine and Therapeutics (AYL, JCW),The Chinese University of Hong Kong
   and Chinese Medicine Department (ETZ, BFN),Hong Kong Hospital Authority, Hong Kong, China.
NR 0
TC 0
SN 1536-596
EI 0025-797
J9 Medicine (Baltimore)
PD MAR 6
PY 2016
VL 95
IS 9
BP e2901
EP e2901
DI 10.1097/MD.0000000000002901
PG 1
WC Acupuncture Therapy; Humans; Neoplasms; Palliative Care; methods
UT PubMed:26945382
PM 26945382
DA 2016-03-06
ER

PT J
AU Boyd, C
   Crawford, C
   Paat, CF
   Price, A
   Xenakis, L
   Zhang, WM
AF Boyd, Courtney
   Crawford, Cindy
   Paat, Charmagne F.
   Price, Ashley
   Xenakis, Lea
   Zhang, Weimin
TI The Impact of Massage Therapy on Function in Pain Populations-A Systematic Review and Meta-Analysis of Randomized Controlled Trials: Part II, Cancer Pain Populations
SO PAIN MEDICINE
LA English
DT Review
DE Systematic Review; Meta-Analysis; Massage Therapy; Pain; Function; Health-Related Quality of Life
ID rapid evidence assessment; breast-cancer; acupuncture research; interventions; women; aromatherapy; military; mood; care
AB Purpose. Pain is multi-dimensional and may be better addressed through a holistic, biopsychosocial approach. Massage therapy is commonly practiced among patients seeking pain management; however, its efficacy is unclear. This systematic review and meta-analysis is the first to rigorously assess the quality of massage therapy research and evidence for its efficacy in treating pain, function-related and health-related quality of life in cancer populations. Methods. Key databases were searched from inception through February 2014. Eligible randomized controlled trials were assessed for methodological quality using the SIGN 50 Checklist. Meta-analysis was applied at the outcome level. A diverse steering committee interpreted the results to develop recommendations. Results. Twelve high quality and four low quality studies were subsequently included in the review. Results demonstrate massage therapy is effective for treating pain compared to no treatment [standardized mean difference (SMD) = -.20] and active (SMD = -0.55) comparators. Compared to active comparators, massage therapy was also found to be beneficial for treating fatigue (SMD = -1.06) and anxiety (SMD = -1.24). Conclusion. Based on the evidence, weak recommendations are suggested for massage therapy, compared to an active comparator, for the treatment of pain, fatigue, and anxiety. No recommendations were suggested for massage therapy compared to no treatment or sham control based on the available literature to date. This review addresses massage therapy safety, research challenges, how to address identified research gaps, and necessary next steps for implementing massage therapy as a viable pain management option for cancer pain populations.
C1 [Boyd, Courtney; Crawford, Cindy; Paat, Charmagne F.; Price, Ashley; Xenakis, Lea; Zhang, Weimin; Evidence Massage Therapy EMT] Samueli Inst, 1737 King St,Suite 600, Alexandria, VA 22314 USA.
RP Boyd, C (corresponding author), Samueli Inst, 1737 King St,Suite 600, Alexandria, VA 22314 USA.
EM cboyd@samueliinstitute.org
FU Massage Therapy Foundation, through the American Massage Therapy Association
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NR 61
TC 63
Z9 77
U1 0
U2 28
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 1526-2375
EI 1526-4637
J9 PAIN MED
JI Pain Med.
PD AUG 15
PY 2016
VL 17
IS 8
BP 1553
EP 1568
DI 10.1093/pm/pnw100
PG 16
WC Anesthesiology; Medicine, General & Internal
SC Anesthesiology; General & Internal Medicine
GA DZ1WQ
UT WOS:000385632800017
PM 27165967
DA 2026-01-16
ER

PT J
AU Minchom, A
   Punwani, R
   Filshie, J
   Bhosle, J
   Nimako, K
   Myerson, J
   Gunapala, R
   Popat, S
   O'Brien, MER
AF Minchom, A.
   Punwani, R.
   Filshie, J.
   Bhosle, J.
   Nimako, K.
   Myerson, J.
   Gunapala, R.
   Popat, S.
   O'Brien, M. E. R.
TI A randomised study comparing the effectiveness of acupuncture or morphine versus the combination for the relief of dyspnoea in patients with advanced non-small cell lung cancer and mesothelioma
SO EUROPEAN JOURNAL OF CANCER
LA English
DT Article
DE Lung cancer; Acupuncture; Dyspnoea
ID controlled-trial; palliative care; placebo; breathlessness; pain
AB Background: Dyspnoea is one of the commonest symptoms of lung cancer. Opioids can reduce dyspnoea. This study investigates acupuncture for relief of breathlessness in lung cancer. Methods: We performed a single-centre, randomised phase II study of 173 patients with non-small cell lung cancer or mesothelioma with dyspnoea score of >= 4 on visual analogue scale (VAS). Randomisation was to acupuncture alone (A), morphine alone (M) or both (AM). Acupuncture was administered at upper sternal, thoracic paravertebral, trapezius trigger points and LI4. Manubrial semi-permanent acupuncture studs were inserted and massaged when symptomatic. Arm A patients received rescue morphine. Primary end-point was proportion of patients achieving >= 1.5 improvement in VAS dyspnoea at 4 h. Measurements continued to day 14 and included VAS relaxation, line analogue rating (Lar) anxiety, hospital anxiety and depression and European Organisation for Research and Treatment of Cancer quality-of-life scores. Results: Dyspnoea VAS improved >= 1.5 in 74%, 60% and 66% of arms A, M and AM, respectively, and was maintained in 45% at 2 weeks. There was no statistically significant difference between arms. VAS relaxation improved in arms A (1.06 points) and AM (1.48 points) compared to arm M (-0.19 points, p < 0.001). At 7 d, the Lar anxiety score improved in arm A (1.5 points), arm AM (1.2 points) and arm M (no change, p=0.003). Fewer patients received at least one morphine dose in arm A compared with arm M or AM (21% versus 87% versus 87%, respectively, p < 0.001). Conclusions: A, M and AM were effective in relieving dyspnoea. Acupuncture relieved anxiety and was morphine sparing, providing an alternative to morphine. (C) 2016 Elsevier Ltd. All rights reserved.
C1 [Minchom, A.; Punwani, R.; Bhosle, J.; Nimako, K.; Myerson, J.; Gunapala, R.; Popat, S.; O'Brien, M. E. R.] Royal Marsden Hosp, Lung Unit, Sutton, Surrey, England.
   [Filshie, J.] Royal Marsden Hosp, Dept Anaesthet & Pain Management, Sutton, Surrey, England.
C3 Royal Marsden NHS Foundation Trust; Royal Marsden NHS Foundation Trust
RP O'Brien, MER (corresponding author), Royal Marsden Hosp, Lung Unit, Sutton, Surrey, England.
EM mary.o'brien@rmh.nhs.uk
FU National Institute for Health Research Biomedical Research Centre; Aqualung Charity [1108352]
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NR 28
TC 38
Z9 45
U1 1
U2 39
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0959-8049
EI 1879-0852
J9 EUR J CANCER
JI Eur. J. Cancer
PD JUL 15
PY 2016
VL 61
IS 
BP 102
EP 110
DI 10.1016/j.ejca.2016.03.078
PG 9
WC Oncology
SC Oncology
GA DN9FK
UT WOS:000377384700013
PM 27156228
DA 2026-01-16
ER

PT J
AU de, Valois B
   Asprey, A
   Young, T
AF de Valois, Beverley
   Asprey, Anthea
   Young, Teresa
TI "The Monkey on Your Shoulder": A Qualitative Study of Lymphoedema Patients'
SO Evidence-based complementary and alternative medicine : eCAM
LA English
DT Journal Article
AB Background. Lymphoedema, a distressing consequence of cancer treatment, has  significant negative impact on health-related quality of life. Multidisciplinary  approaches are needed to improve physical and psychosocial wellbeing. Acupuncture  and moxibustion (acu/moxa), two modalities of traditional East Asian medicine,  may contribute to improved outcomes for cancer survivors with lymphoedema. Aim.  To explore how patients with lymphoedema secondary to cancer treatment perceive  and experience acu/moxa treatment. Design and Setting. A qualitative focus group  study, nested in a 3-step mixed methods observational study, was carried out in a  cancer drop-in and information centre in north-west London. Methods. Six focus  groups and one telephone interview were conducted with 23 survivors of breast or  head and neck cancer, who had completed up to 13 acu/moxa treatments. Scripts  were transcribed, coded, and analysed to identify salient and overarching themes.  Results. Participants described feeling disempowered by cancer treatment and  subsequent diagnosis of lymphoedema. Acu/moxa was valued for its whole-person  approach and for time spent with a practitioner who cared, listened, and  responded. Participants reported changes in physical and psychosocial health,  including increased energy levels and reduced pain and discomfort, and feelings  of empowerment, personal control, and acceptance. Many were motivated to improve  self-care. Conclusion. Many participants who received acu/moxa treatment reported  improved wellbeing and a more proactive attitude towards self-care.
C1 Supportive Oncology Research Team, Lynda Jackson Macmillan Centre, Mount Vernon Cancer Centre, Rickmansworth Road, Northwood, Middlesex HA6 2RN, UK.
   University of Exeter Medical School, Magdalen Road, Exeter EX1 2LU, UK.
   Supportive Oncology Research Team, Lynda Jackson Macmillan Centre, Mount Vernon Cancer Centre, Rickmansworth Road, Northwood, Middlesex HA6 2RN, UK.
NR 0
TC 0
SN 1741-428
EI 1741-427
J9 Evid Based Complement Alternat Med
PD SEP 16
PY 2016
VL 2016
IS 
BP 4298420
EP 4298420
DI 10.1155/2016/4298420
PG 0
UT PubMed:27630734
PM 27630734
DA 2016-09-16
ER

PT J
AU Chao, MT
   Chang, A
   Reddy, S
   Harrison, JD
   Acquah, J
   Toveg, M
   Santana, T
   Hecht, FM
AF Chao, Maria T
   Chang, Alexandra
   Reddy, Sanjay
   Harrison, James D
   Acquah, Joseph
   Toveg, Miria
   Santana, Trilce
   Hecht, Frederick M
TI Adjunctive acupuncture for pain and symptom management in the inpatient setting:
SO Journal of integrative medicine
LA English
DT Journal Article
AB BACKGROUND: Effective pain management among hospitalized patients is an important  aspect of providing quality care and achieving optimal clinical outcomes and  patient satisfaction. Common pharmacologic approaches for pain, though effective,  have serious side effects and are not appropriate for all inpatients. Findings  from randomized controlled trials (RCTs) support the efficacy of acupuncture for  many symptoms relevant to inpatients including postoperative pain, cancer-related  pain, nausea and vomiting, and withdrawal from narcotic use. However, the extent  to which findings from RCTs translate to real-world implementation of acupuncture  in typical hospital settings is unknown. METHODS/DESIGN: In partnership with the  launch of a clinical program offering acupuncture services to inpatients at the  University of California San Francisco's Mount Zion Hospital, we are conducting a  pilot study using a hybrid effectiveness-implementation design to: (1) assess the  effectiveness of acupuncture to manage pain and other symptoms and improve  patient satisfaction; and (2) evaluate the barriers and facilitators to  implementing an on-going acupuncture service for inpatients. During a two-month  pre-randomization phase, we evaluated and adapted clinical scheduling and  treatment protocols with acupuncturists and hospital providers and pretested  study procedures including enrollment, consent, and data collection. During a  six-month randomization phase, we used a two-tiered consent process in which  inpatients were first consented into a study of symptom management, randomized to  be offered acupuncture, and consented for acupuncture if they accepted. We are  also conducting in-depth interviews and focus groups to assess evidence, context,  and facilitators of key provider and hospital administration stakeholders.  DISCUSSION: Effectiveness research in "real-world" practice settings is needed to  inform clinical decision-making and guide implementation of evidence-based  acupuncture practices. To successfully provide clinical acupuncture services and  maintain a rigorous research design, practice-based trials of acupuncture require  careful planning and attention to setting-specific, contextual factors. TRIAL  REGISTRATION: This trial has been registered in ClinicalTrials.gov. The  identifier is NCT01988194, registered on November 5, 2013.
C1 Osher Center for Integrative Medicine, University of California San Francisco, San Francisco, California 94143, USA.
   Division of General Internal Medicine, Zuckerberg San Francisco General Hospital, 
   Departments of Anesthesiology and Internal Medicine, Loma Linda University, Loma Linda, California 92354, USA.
   Osher Center for Integrative Medicine, University of California San Francisco, San Francisco, California 94143, USA.
   Division of Hospital Medicine, University of California San Francisco, San 
   Division of Hospital Medicine, University of California San Francisco, San Francisco, California 94143, USA.
   Osher Center for Integrative Medicine, University of California San Francisco, San Francisco, California 94143, USA.
   Osher Center for Integrative Medicine, University of California San Francisco, San Francisco, California 94143, USA.
   Osher Center for Integrative Medicine, University of California San Francisco, San Francisco, California 94143, USA.
   Osher Center for Integrative Medicine, University of California San Francisco, San Francisco, California 94143, USA.
NR 0
TC 0
SN 
EI 2095-496
J9 J Integr Med
PD MAY 18
PY 2016
VL 14
IS 3
BP 228
EP 38
DI 10.1016/S2095-4964(16)60252-2
PG -190
WC Acupuncture Therapy; Clinical Protocols; Humans; Inpatients; Pain Management; Pilot Projects
UT PubMed:27181130
PM 27181130
DA 2016-05-18
ER

PT J
AU Tao, WW
   Jiang, H
   Tao, XM
   Jiang, P
   Sha, LY
   Sun, XC
AF Tao, Wei-Wei
   Jiang, Hua
   Tao, Xiao-Mei
   Jiang, Ping
   Sha, Li-Yan
   Sun, Xian-Ce
TI Effects of Acupuncture, Tuina, Tai Chi, Qigong, and Traditional Chinese Medicine
SO Journal of pain and symptom management
LA English
DT Review
DE Acupuncture; Qigong; Tai Chi; cancer; massage; meta-analysis; symptom management
AB CONTEXT: Most cancer patients suffer from both the disease itself and symptoms  induced by conventional treatment. Available literature on the clinical effects  on cancer patients of acupuncture, Tuina, Tai Chi, Qigong, and Traditional  Chinese Medicine Five-Element Music Therapy (TCM-FEMT) reports controversial  results. OBJECTIVES: The primary objective of this meta-analysis was to evaluate  the effect of acupuncture, Tuina, Tai Chi, Qigong, and TCM-FEMT on various  symptoms and quality of life (QOL) in patients with cancer; risk of bias for the  selected trials also was assessed. METHODS: Studies were identified by searching  electronic databases (MEDLINE via both PubMed and Ovid, Cochrane Central, China  National Knowledge Infrastructure, Chinese Scientific Journal Database, China  Biology Medicine, and Wanfang Database). All randomized controlled trials (RCTs)  using acupuncture, Tuina, Tai Chi, Qigong, or TCM-FEMT published before October  2, 2014, were selected, regardless of whether the article was published in  Chinese or English. RESULTS: We identified 67 RCTs (5465 patients) that met our  inclusion criteria to perform this meta-analysis. Analysis results showed that a  significant combined effect was observed for QOL change in patients with terminal  cancer in favor of acupuncture and Tuina (Cohen's d: 0.21-4.55, P < 0.05),  whereas Tai Chi and Qigong had no effect on QOL of breast cancer survivors (P >  0.05). The meta-analysis also demonstrated that acupuncture produced  small-to-large effects on adverse symptoms including pain, fatigue, sleep  disturbance, and some gastrointestinal discomfort; however, no significant effect  was found on the frequency of hot flashes (Cohen's d = -0.02; 95% CI = -1.49 to  1.45; P = 0.97; I(2) = 36%) and mood distress (P > 0.05). Tuina relieved  gastrointestinal discomfort. TCM-FEMT lowered depression level. Tai Chi improved  vital capacity of breast cancer patients. High risk of bias was present in 74.63%  of the selected RCTs. Major sources of risk of bias were lack of blinding,  allocation concealment, and incomplete outcome data. CONCLUSION: Taken together,  although there are some clear limitations regarding the body of research reviewed  in this study, a tentative conclusion can be reached that acupuncture, Tuina, Tai  Chi, Qigong, or TCM-FEMT represent beneficial adjunctive therapies. Future study  reporting in this field should be improved regarding both method and content of  interventions and research methods.
C1 College of Nursing, Dalian Medical University, Dalian, People's Republic of China. 
   School of Nursing, Peking University, Beijing, People's Republic of China.
   Beijing Shijitan Hospital, Beijing, People's Republic of China.
   Graduate School, Dalian Medical University, Dalian, People's Republic of China. 
   College of Nursing, Dalian Medical University, Dalian, People's Republic of China.
   College of Public Health, Dalian Medical University, Dalian, People's Republic of China.
EM dywx.2009@163.com
NR 0
TC 0
SN 1873-651
EI 
J9 J Pain Symptom Manage
PD FEB 18
PY 2016
VL 51
IS 4
BP 728
EP 747
DI 10.1016/j.jpainsymman.2015.11.027
PG 19
WC Acupuncture Therapy; Disease Management; Humans; Medicine, Chinese Traditional; methods; Music Therapy; methods; Neoplasms; physiopathology; Qigong; Quality of Life; Randomized Controlled Trials as Topic; Tai Ji
UT PubMed:26880252
PM 26880252
DA 2016-02-18
ER

PT J
AU Sima, L
   Fan, BF
   Yan, LT
   Shui, Y
AF Sima, Lei
   Fan, Bifa
   Yan, Longtao
   Shui, Yuan
TI Effects of Electroacupuncture Treatment on Bone Cancer Pain Model with Morphine Tolerance
SO EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
LA English
DT Article
ID gene-related peptide; neuropathic pain
AB Objective. To explore the efficacy of electroacupuncture treatment in cancer induced bone pain (CIBP) rat model with morphine tolerance and explore changes of calcitonin-gene related peptide (CGRP) expression in dorsal root ganglion (DRG). Methods. Forty SD rats were divided into five groups: sham, CIBP (B), CIBP + morphine (BM), CIBP + electroacupuncture (BE), and CIBP + morphine + electroacupuncture (BME). B, BM, BE, and BME groups were prepared CIBP model. The latter three groups then accepted morphine, electroacupuncture, and morphine combined electroacupuncture, separately, nine days consecutively (M1 to M9). Mechanical withdraw threshold(MWT) was evaluated. Results. BE group only had differences in M1, M2, and M3 compared to B group (P < 0.01). From M5, BM group showed significantly decreased MWT. Electroacupuncture could obtain analgesic effects only at early stage (M1 to M5). From M5 to M9, BME had the differences with BM group (P < 0.01). IOD value of CGRP in BM and BME was substantially less than in B group. CGRP in BME was significantly lower than that in BM group (P < 0.01). Conclusion. When used in combination with electroacupuncture, morphine could result in improving analgesic effects and reducing tolerance. CGRP may be associated with pain behaviors.
C1 [Sima, Lei; Fan, Bifa; Yan, Longtao; Shui, Yuan] China Japan Friendship Hosp, Natl Pain Management & Res Ctr, Beijing, Peoples R China.
C3 China-Japan Friendship Hospital
RP Sima, L (corresponding author), China Japan Friendship Hosp, Natl Pain Management & Res Ctr, Beijing, Peoples R China.
EM simalei75@126.com
FU National Natural Science Foundation of China [81403253]
CR Chen TY, 2016, EVID-BASED COMPL ALT, V2016, P0, DOI 10.1155/2016/2126416
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NR 17
TC 6
Z9 7
U1 0
U2 8
PU HINDAWI LTD
PI LONDON
PA ADAM HOUSE, 3RD FLR, 1 FITZROY SQ, LONDON, W1T 5HF, ENGLAND
SN 1741-427X
EI 1741-4288
J9 EVID-BASED COMPL ALT
JI Evid.-based Complement Altern. Med.
PD JUN 15
PY 2016
VL 2016
IS 
BP 
EP 
DI 10.1155/2016/8028474
PG 5
WC Integrative & Complementary Medicine
SC Integrative & Complementary Medicine
GA DW2LS
UT WOS:000383474500001
PM 27672401
DA 2026-01-16
ER

PT J
AU Oh, B
   Eade, T
   Kneebone, A
   Pavlakis, N
   Clarke, S
   Eslick, G
   River, J
   Back, M
AF Oh, Byeongsang
   Eade, Thomas
   Kneebone, Andrew
   Pavlakis, Nick
   Clarke, Stephen
   Eslick, Guy
   River, Jo
   Back, Michael
TI Factors affecting whether or not cancer patients consider using acupuncture.
SO Acupuncture in medicine : journal of the British Medical Acupuncture Society
LA English
DT Journal Article
DE ACUPUNCTURE; ONCOLOGY
AB OBJECTIVE: To explore the factors associated with utilisation of an acupuncture  service in a tertiary oncology setting in an Australian public hospital. METHOD:  Cancer patients attending oncology clinics at a university teaching hospital were  invited to participate in the evaluation of acupuncture services from June 2014  to May 2015. Patients had a prior diagnosis of cancer (albeit at different  stages) and were planning to receive, or were already receiving, systemic and/or  radiation cancer treatment. RESULTS: The majority (81%) of participants indicated  that they would consider the use of acupuncture during their cancer treatment.  The most common reasons given for not considering acupuncture included adequate  control of symptoms already with medical treatment, inconvenient clinic timing,  and needle phobia. The main reasons given for considering acupuncture use  included its perceived capability of reducing fatigue, boosting energy levels,  improving immune function, and reducing pain and anxiety. Patients considering  acupuncture use also demonstrated significantly higher levels of stress  (p<0.001), anxiety and depression (p<0.001), fatigue (p<0.001), and lower global  quality of life (p<0.01) compared to those who were not considering acupuncture.  CONCLUSIONS: The findings show that demand for acupuncture by cancer patients is  high. A substantial proportion of cancer patients intend to use acupuncture to  manage cancer and/or cancer treatment-related symptoms. Discussion with patients  about acupuncture and other complementary therapies during the consultation may  improve cancer care.
C1 Northern Sydney Cancer Centre, Royal North Shore Hospital, Sydney, New South Wales, Australia.
   Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia.
   Harvard Medical School, Boston, Massachusetts, USA.
   Northern Sydney Cancer Centre, Royal North Shore Hospital, Sydney, New South Wales, Australia.
   Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia.
   Northern Sydney Cancer Centre, Royal North Shore Hospital, Sydney, New South Wales, Australia.
   Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia.
   Northern Sydney Cancer Centre, Royal North Shore Hospital, Sydney, New South Wales, Australia.
   Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia.
   Northern Sydney Cancer Centre, Royal North Shore Hospital, Sydney, New South Wales, Australia.
   Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia.
   Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia.
   Sydney Nursing School, University of Sydney, Camperdown, New South Wales, Australia.
   Northern Sydney Cancer Centre, Royal North Shore Hospital, Sydney, New South Wales, Australia.
   Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia.
NR 0
TC 0
SN 1759-987
EI 
J9 Acupunct Med
PD SEP 24
PY 2016
VL 35
IS 2
BP 107
EP 113
DI 10.1136/acupmed-2016-011115
PG 6
WC Acupuncture Therapy; Adolescent; Adult; Aged; Anxiety; etiology; Australia; Cross-Sectional Studies; Fatigue; etiology; Female; Humans; Male; Middle Aged; Neoplasms; complications; Pain; etiology; Pain Management; Quality of Life; Young Adult
UT PubMed:27658799
PM 27658799
DA 2016-09-24
ER

PT J
AU Kwekkeboom, KL
AF Kwekkeboom, Kristine L
TI Cancer Symptom Cluster Management.
SO Seminars in oncology nursing
LA English
DT Review
DE clinical practice; patient education; symptom cluster; symptom management; therapeutics
AB OBJECTIVES: To discuss the importance of cancer symptom clusters in clinical  practice, review evidence for symptom cluster interventions, and make  recommendations for symptom cluster identification, patient education, and  management in clinical practice. DATA SOURCES: Primary research and review  articles identified through CINAHL, PubMed, and PsycINFO databases. CONCLUSION:  Several studies have investigated interventions for multi-symptom management or  have evaluated the secondary effects of a single-symptom intervention on related  symptoms. To date, only five studies have tested an intervention designed to  manage a specific cancer symptom cluster. Those studies used nonpharmacologic  approaches (psycho-education, cognitive-behavioral strategies, and acupressure)  to address the pain, fatigue, and sleep disturbance symptom cluster, or the  respiratory distress symptom cluster with some initial evidence of success.  Further development and efficacy testing of symptom cluster interventions is  needed. IMPLICATIONS FOR NURSING PRACTICE: Clinical practice can be guided by  knowledge of individual and multi-symptom management, and clinical judgment  regarding possible etiologies of cancer symptom clusters. Clinicians should be  aware of co-occurring symptoms in their patients, educate and involve patients in  identifying symptom clusters and aggravating/alleviating factors, and coordinate  treatment recommendations using strategies that are likely to be beneficial  across symptoms.
NR 0
TC 0
SN 1878-344
EI 0749-208
J9 Semin Oncol Nurs
PD OCT 30
PY 2016
VL 32
IS 4
BP 373
EP 382
DI 10.1016/j.soncn.2016.08.004
PG 9
WC Fatigue; Humans; Neoplasms; complications; Pain; Sleep Wake Disorders; Symptom Assessment; Syndrome
UT PubMed:27789073
PM 27789073
DA 2016-10-30
ER

PT J
AU Lahoud, MJ
   Kourie, HR
   Antoun, J
   El Osta, L
   Ghosn, M
AF Lahoud, Marie Jose
   Kourie, Hampig Raphael
   Antoun, Joelle
   El Osta, Lana
   Ghosn, Marwan
TI Road map for pain management in pancreatic cancer: A review
SO WORLD JOURNAL OF GASTROINTESTINAL ONCOLOGY
LA English
DT Review
DE Pain management; Interventional; Medical; Treatment; Pancreatic cancer
ID placebo-controlled trial; celiac plexus block; endoscopic ultrasound; neuropathic pain; double-blind; pregabalin; morphine; survival; adenocarcinoma; innervation
AB Beside its poor prognosis and its late diagnosis, pancreatic cancer remains one of the most painful malignancies. Optimal management of pain in this cancer represents a real challenge for the oncologist whose objective is to ensure a better quality of life to his patients. We aimed in this paper to review all the treatment modalities incriminated in the management of pain in pancreatic cancer going from painkillers, chemotherapy, radiation therapy and interventional techniques to agents under investigation and alternative medicine. Although specific guidelines and recommendations for pain management in pancreatic cancer are still absent, we present all the possible pain treatments, with a progression from medical multimodal treatment to radiotherapy and chemotherapy then interventional techniques in case of resistance. In addition, alternative methods such as acupuncture and hypnosis can be added at any stage and seems to contribute to pain relief.
C1 [Lahoud, Marie Jose] St Joseph Univ, Dept Anesthesiol & Crit Care, Fac Med, Beirut 166830, Lebanon.
   [Kourie, Hampig Raphael; Antoun, Joelle; El Osta, Lana; Ghosn, Marwan] St Joseph Univ, Dept Oncol, Fac Med, Monot St, Beirut 166830, Lebanon.
RP Ghosn, M (corresponding author), St Joseph Univ, Dept Oncol, Fac Med, Monot St, Beirut 166830, Lebanon.
EM marwanghosnmd@yahoo.com
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NR 77
TC 41
Z9 45
U1 2
U2 24
PU BAISHIDENG PUBLISHING GROUP INC
PI PLEASANTON
PA 7041 Koll Center Parkway, Suite 160, PLEASANTON, CA, UNITED STATES
SN 1948-5204
EI 
J9 WORLD J GASTRO ONCOL
JI World J. Gastrointest. Oncol.
PD AUG 15
PY 2016
VL 8
IS 8
BP 599
EP 606
DI 10.4251/wjgo.v8.i8.599
PG 8
WC Oncology; Gastroenterology & Hepatology
SC Oncology; Gastroenterology & Hepatology
GA FE9TJ
UT WOS:000408545800003
PM 27574552
DA 2026-01-16
ER

PT J
AU Yan, Z
   Huang, W
   Li, S
   Zhang, W
   Hu, Y
   Liu, Chunjing
AF Yan, Zhongkai
   Huang, Wei
   Li, Suli
   Zhang, Weijing
   Hu, Yuqing
   Liu Chunjing
TI [Impact of huolong moxibustion on TNF-α and pain degree in the patients of
SO Zhongguo zhen jiu = Chinese acupuncture & moxibustion
LA chi
DT Journal Article
AB OBJECTIVE: To discuss the impact of huolong moxibustion on pain degree in the  patients of discogenic low back pain and the effect mechanism. METHODS:  Sixty-five patients were randomized into an observation group (33 cases) and a  control group (32 cases). In the observation group, huolong moxibustion was  applied along the distribution of the Governor Vessel, once a day. In the control  group, the routine traction combined with massage therapy was adopted, once a  day. In the two groups, the treatment was given 6 times a week, at interval of 1  day. In 3 weeks of treatment, pain score and serum tumor necrosis factor α  (TNF-α) level were compared with those before treatment in the two groups.  RESULTS: Compared with those before treatment, pain score and TNF-α level were  reduced significantly after treatment in the two groups (both P < 0.05). The  results in the observation group were lower than those in the control group (pain  score: 1.95 ± 0.61 vs 2.11 ± 0.61; TNF-α: (1.33 ± 0.30) nmol/L vs (1.55 ± 0.48)  nmol/L, (both P < 0.05). CONCLUSION: Huolong moxibustion significantly alleviates  pain in the patients of discogenic low back pain and its effect mechanism is  possibly relevant with TNF-α reducing.
NR 0
TC 0
SN 
EI 0255-293
J9 Zhongguo Zhen Jiu
PD MAR 5
PY 2016
VL 35
IS 11
BP 1121
EP 3
DI 
PG -1118
WC Adult; Female; Humans; Low Back Pain; metabolism; Male; Massage; Middle Aged; Moxibustion; Pain Measurement; Traction; Tumor Necrosis Factor-alpha; metabolism; Young Adult
UT PubMed:26939323
PM 26939323
DA 2016-03-05
ER

PT J
AU Hsieh, YL
   Chou, LW
   Hong, SF
   Chang, FC
   Tseng, SW
   Huang, CC
   Yang, CH
   Yang, CC
   Chiu, WF
AF Hsieh, Yueh-Ling
   Chou, Li-Wei
   Hong, Shao-Fu
   Chang, Fei-Chi
   Tseng, Szu-Wen
   Huang, Chi-Chou
   Yang, Ching-Hsiang
   Yang, Chen-Chia
   Chiu, Wei-Feng
TI Laser acupuncture attenuates oxaliplatin-induced peripheral neuropathy in
SO Acupuncture in medicine : journal of the British Medical Acupuncture Society
LA English
DT Journal Article
DE ONCOLOGY
AB BACKGROUND: Oxaliplatin is a platinum compound that is widely used in the  treatment of some solid tumours. Oxaliplatin-induced peripheral neuropathy (OIPN)  in the upper and lower extremities is the major adverse side effect and  represents the main dose-limiting factor of this drug. The aim of this single-arm  study was to evaluate the feasibility and effects of laser acupuncture (LA) in  the treatment of OIPN in patients with advanced gastrointestinal cancers.  METHODS: 17 gastrointestinal cancer survivors (14 colorectal and 3 gastric  cancers), who had been treated with oxaliplatin-based chemotherapies, were  recruited. Low-level laser stimulation (50 mW) bilaterally at PC6, PC7, PC8, P9,  LU11, SP6, KI3, BL60, KI1, and KI2 was administered for 20 min/point for 12  sessions over 4 weeks. The pain quality assessment scale (PQAS),  chemotherapy-induced neurotoxicity questionnaire (CINQ), oxaliplatin-specific  neurotoxicity scale (OSNS), quantitative touch-detection threshold (using von  Frey filaments), and cold-triggered pain withdrawal latency (using the cold-water  immersion test) were measured before and after completion of the 12 treatment  sessions. RESULTS: PQAS, CINQ, and OSNS scores, as well as touch-detection  threshold and cold-trigger pain withdrawal latency all improved significantly  after LA in the cancer patients with OIPN (p<0.05). LA significantly relieved  both oxaliplatin-induced cold and mechanical allodynia and also decreased the  incidence and severity of neurotoxicity symptoms in the patients' upper and lower  extremities and impact on their daily activities (all p<0.05). CONCLUSIONS:  Following treatment with LA, neurotoxicity symptoms were significantly improved  in cancer patients with OIPN. Further randomised controlled trials are needed to  evaluate the role of LA as a therapeutic option in the management of OIPN.
C1 Department of Physical Therapy, Graduate Institute of Rehabilitation Science, China Medical University, Taichung, Taiwan.
   Graduate Institute of Acupuncture Science, College of Chinese Medicine, China Medical University, Taichung, Taiwan Department of Physical Medicine andRehabilitation, China Medical University Hospital, Taichung, Taiwan.
   Department of Physical Therapy, Graduate Institute of Rehabilitation Science, China Medical University, Taichung, Taiwan Department of Physical Medicine andRehabilitation, Chung Shan Medical University Hospital Chung Shing Branch,Taichung, Taiwan.
   Nursing Department, Chung Shan Medical University Hospital, Taichung, Taiwan.
   Department of Internal Medicine, Division of Medical Oncology, Chung Shan Medical University Hospital, Taichung, Taiwan.
   School of Medicine, Chung Shan Medical University, Taichung, Taiwan Department of Surgery, Division of Colon and Rectum, Chung Shan Medical University Hospital,Taichung, Taiwan.
   Department of Physical Therapy, Graduate Institute of Rehabilitation Science, China Medical University, Taichung, Taiwan.
   Department of Physical Medicine and Rehabilitation, Cheng Ching General Hospital, Taichung, Taiwan.
   Department of Physical Medicine and Rehabilitation, Cheng Ching General Hospital, Taichung, Taiwan.
NR 0
TC 0
SN 1759-987
EI 
J9 Acupunct Med
PD SEP 11
PY 2016
VL 34
IS 5
BP 398
EP 405
DI 10.1136/acupmed-2016-011112
PG 7
WC Acupuncture Therapy; methods; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; adverse effects; Female; Gastrointestinal Neoplasms; drug therapy; Humans; Laser Therapy; methods; Male; Middle Aged; Organoplatinum Compounds; adverse effects; Oxaliplatin; Pain; etiology; Peripheral Nervous System Diseases; chemically induced; Pilot Projects; Prospective Studies; Treatment Outcome
UT PubMed:27613370
PM 27613370
DA 2016-09-11
ER

PT J
AU Sui, M
   Lessans, S
   Yan, T
   Cao, D
   Lao, L
   Dorsey, SG
AF Sui, Minghong
   Lessans, Sherrie
   Yan, Tiebin
   Cao, Dongyuan
   Lao, Lixing
   Dorsey, Susag G
TI [Mechanism of electroacupuncture on "Zusanli (ST 36)" for chemotherapy-induced
SO Zhongguo zhen jiu = Chinese acupuncture & moxibustion
LA chi
DT Journal Article
AB OBJECTIVE: To observe the effects and duration of electroacupuncture on the  mechanical pain threshold induced by paclitaxel and explore its analgesic  mechanism. METHODS: Sixty-four C57BL/6J male mice were randomly divided into 4  groups, a normal+sham EA group, a normal+EA group, a medicine+sham EA(Med+ sham  EA) group, a medicine + EA (Med + EA) group, 16 cases in each group. The model of  chemotherapy-induced peripheral neuropathy was established with paclitaxel  intraperitoneal injection on the 1st, 3rd, 5th, 7th day in the Med + sham EA  group and the Med + EA group. EA of 30 min was used on bilateral "Zusanli (ST  36)" on the 9th, 11th, 13th, 16th, 18th, 20th, 23rd, 25th, 27th, 30th day in the  EA groups, 2 Hz/100 Hz and 1~ 1.5 mA. Acupuncture was applied on the same  acupoint at the same times in the sham EA groups. Mechanical pain thresholds were  tested by VonFrey before and after model establishment, namely on the 8th, 14th;  21st and, 28th day. The heart blood of 8 mice was drawn quickly to collect serum  in every group on the 31st day, and the contents of tumor necrosis factor α  (TNF-α), interleukin-1α (IL-1α), interleukin-1β (IL-1β) in proinflammatory  cytokine were examined by ELISA. Mechanical pain thresholds were tested by  VonFrey for the rest 8 mice of each group until there was no apparent difference  in the two paclitaxel groups once a week,namely on the 35th, 42nd, 49th day.  RESULTS: The pain thresholds of each group were not statistically different  before model establishment (P > 0.05). After model establishment (on the 8th  day), thresholds of the paclitaxel groups were lower than those of the normal  groups (all P < 0.05). After EA, the mechanical pain thresholds of the Med + EA  group were higher than those of the Med + sham EA group at all the time points,  and there was statistical difference on the 14th, 21st and 28th day (all P <  0.05). The analgesic effect was lasting to the 49th day. The contents of TNF-α,  IL-1α, IL-1β of the Med + EA group were decreased than those of the Med+sham EA  group in different degree, with statistical significance of IL-1α (P < 0.05).  CONCLUSION: EA can effectively treat paclitaxel-induced peripheral neuropathy,and  the analgesic mechanism is probably related to decreasing the proinflammatory  cytokine.
NR 0
TC 0
SN 
EI 0255-293
J9 Zhongguo Zhen Jiu
PD AUG 12
PY 2016
VL 36
IS 5
BP 512
EP 6
DI 
PG -506
WC Acupuncture Points; Animals; Antineoplastic Agents; administration & dosage; Electroacupuncture; Humans; Interleukin-1beta; genetics; Male; Mice; Mice, Inbred C57BL; Neoplasms; drug therapy; Peripheral Nervous System Diseases; etiology; Tumor Necrosis Factor-alpha; genetics
UT PubMed:27509614
PM 27509614
DA 2016-08-12
ER

PT J
AU Quinlan-Woodward, J
   Gode, A
   Dusek, JA
   Reinstein, AS
   Johnson, JR
   Sendelbach, S
AF Quinlan-Woodward, Jessica
   Gode, Autumn
   Dusek, Jeffery A
   Reinstein, Adam S
   Johnson, Jill R
   Sendelbach, Sue
TI Assessing the Impact of Acupuncture on Pain, Nausea, Anxiety, and Coping in Women
SO Oncology nursing forum
LA English
DT Journal Article
DE acupuncture ; anxiety; breast cancer; nausea/vomiting; pain
AB PURPOSE/OBJECTIVES: To compare the effect of acupuncture to a standard-of-care  (control) group on pain, nausea, anxiety, and ability to cope.  . DESIGN: Pilot  randomized, controlled trial.  . SETTING: Abbott Northwestern Hospital, a large,  urban, tertiary care hospital in Minneapolis, Minnesota. . SAMPLE: 30 adult women  undergoing surgery for breast cancer. . METHODS: Women were randomly assigned to  two hospital-based acupuncture treatments versus usual care after breast cancer  surgery. Pain, nausea, anxiety, and the patient's ability to cope pre- and  post-treatment were compared within and between groups at two different time  points postoperatively.  . MAIN RESEARCH VARIABLES: Mean change in pain, nausea,  anxiety, and ability to cope by treatment group. . FINDINGS: Compared to women  assigned to the control group, women who received acupuncture reported a  statistically significant greater reduction in pain, nausea, anxiety, and  increase in ability to cope on the first postoperative day and in pain on the  second postoperative day following mastectomy surgery. . CONCLUSIONS: Acupuncture  delivered postoperatively in the hospital after mastectomy can reduce the  severity of symptoms experienced, as well as increase the patient's ability to  cope with her symptoms. However, before implementation as a standard of care,  further research needs to be conducted. . IMPLICATIONS FOR NURSING: Acupuncture  adds a nonpharmacologic intervention for symptom management in women undergoing  mastectomies for breast cancer.
C1 Penny George Institute for Health and Healing.
   Penny George Institute for Health and Healing.
   Penny George Institute for Health and Healing.
   Penny George Institute for Health and Healing.
   Penny George Institute for Health and Healing.
   Abbott Northwestern Hospital.
NR 0
TC 0
SN 1538-068
EI 
J9 Oncol Nurs Forum
PD OCT 22
PY 2016
VL 43
IS 6
BP 725
EP 732
DI 10.1188/16.ONF.725-732
PG 7
WC Acupuncture Therapy; Adaptation, Psychological; Adult; Aged; Aged, 80 and over; Analgesics; therapeutic use; Anti-Anxiety Agents; therapeutic use; Antiemetics; therapeutic use; Anxiety; etiology; Breast Neoplasms; surgery; Female; Humans; Mastectomy; adverse effects; Middle Aged; Minnesota; Nausea; etiology; Pain, Postoperative; etiology; Pilot Projects
UT PubMed:27768139
PM 27768139
DA 2016-10-22
ER

PT J
AU Lee, I
   Garland, SN
   DeMichele, A
   Farrar, JT
   Im, EO
   Mao, JJ
AF Lee, Iris
   Garland, Sheila N
   DeMichele, Angela
   Farrar, John T
   Im, Eun-Ok
   Mao, Jun J
TI A cross-sectional survey of pain catastrophising and acupuncture use among breast
SO Acupuncture in medicine : journal of the British Medical Acupuncture Society
LA English
DT Journal Article
DE ACUPUNCTURE; ONCOLOGY; PAIN MANAGEMENT
AB INTRODUCTION: Treatment-related joint pain affects almost half of all women with  breast cancer using aromatase inhibitors and is a major reason for terminating  treatment. Although acupuncture is becoming an increasingly popular,  evidence-based option for treating pain, little is known about the potential  influence of psychological factors on acupuncture use. OBJECTIVE: We aimed to  evaluate the association between pain catastrophising and use of acupuncture in  breast cancer survivors experiencing arthralgia. METHODS: We conducted a  cross-sectional survey of arthralgic breast cancer patients. Patients were asked  if they had used acupuncture since their cancer diagnosis. The Pain  Catastrophising Scale (PCS) was used to measure negative coping styles related to  the experience of pain. We performed multiple logistic regression analysis to  evaluate the relationship between pain catastrophising and acupuncture use,  adjusting for covariates. RESULTS: Of the 424 participants, 69 (16%) reported use  of acupuncture since their breast cancer diagnosis. In multivariate analyses,  compared to those in the lowest PCS score tertile, patients with the highest PCS  scores were more likely to have used acupuncture (p=0.03). In particular,  patients with high levels of rumination (p=0.005) and magnification (p=0.008)  were more likely to have used acupuncture. Helplessness was not associated with  acupuncture use (p=0.23). CONCLUSIONS: High levels of pain catastrophising, and  specifically the processes of rumination and magnification, were associated with  greater acupuncture use. We believe this could have important implications for  understanding which population is more likely to seek acupuncture treatment and  how this alternative therapy could be better targeted to these patients.
C1 Department of Family Medicine and Community Health, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
   Department of Biostatistics and Epidemiology, Perelman School of Medicine at the 
   Department of Family Medicine and Community Health, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
   Department of Psychology, Memorial University of Newfoundland, St John's, 
   Department of Biostatistics and Epidemiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
   Abramson Cancer Center, Perelman School of Medicine at the University of 
   Department of Biostatistics and Epidemiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
   Abramson Cancer Center, Perelman School of Medicine at the University of 
   Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
   School of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
   Department of Family Medicine and Community Health, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
   Department of Biostatistics and Epidemiology, Perelman School of Medicine at the 
   Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
   The Bendheim Center for Integrative Medicine, Memorial Sloan-Kettering Cancer
NR 0
TC 0
SN 1759-987
EI 
J9 Acupunct Med
PD MAY 15
PY 2016
VL 35
IS 1
BP 38
EP 43
DI 10.1136/acupmed-2016-011056
PG 5
WC Acupuncture Therapy; methods; Aged; Aromatase Inhibitors; adverse effects; Arthralgia; chemically induced; Breast Neoplasms; drug therapy; Catastrophization; chemically induced; Cross-Sectional Studies; Female; Humans; Middle Aged; Pain Measurement; Surveys and Questionnaires; Survivors; psychology; Treatment Outcome
UT PubMed:27177930
PM 27177930
DA 2016-05-15
ER

PT J
AU Zhong, LLD
   Kun, W
   Lam, TF
   Zhang, SP
   Yang, JJ
   Ziea, TC
   Ng, B
   Bian, ZX
AF Zhong, Linda L. D.
   Kun, Wai
   Lam, Tsz Fung
   Zhang, Shi Ping
   Yang, Jun Jun
   Ziea, Tat Chi
   Ng, Bacon
   Bian, Zhao Xiang
TI The combination effects of body acupuncture and auricular acupressure compared to sham acupuncture for body weight control: study protocol for a randomized controlled trial
SO TRIALS
LA English
DT Article
ID clinical-trial; obese adults; metaanalysis; overweight; efficacy; safety; pain
AB Background: Obesity is an increasingly prevalent chronic condition that is associated with serious morbidity and mortality. Excess body weight is a risk factor contributing to diseases such as hypertension, heart disease, hypercholesterolaemia, diabetes mellitus, cerebrovascular disease, gall bladder disease, and some types of cancer. Almost all the Western anti-obesity drugs have adverse effects or body weight is regained upon cessation of therapy. Recent studies have found that acupuncture had a similar efficacy as the Western anti-obesity drugs with fewer reported adverse effects. However, these conclusions were limited due to the small sample size and low quality of methodologies of these studies. Therefore, we design this study to explore the effectiveness and safety of acupuncture on weight control. Methods/design: This is a pilot single-blinded, randomized, sham-controlled trial on acupuncture for body weight control. Seventy-two participants are randomly assigned to the acupuncture group or the control group. Tianshu (ST-25), Daheng (SP-15), Daimai (GB-26), Qihai (CV-6), Zhongwan (CV-12), Zusanli (ST-36), Fenglong (ST-40), and Sanyinjiao (SP-6) are selected as acupuncture points. For the acupuncture group, disposable acupuncture needles will be inserted at a depth of 10-25 mm into the points and electrical stimulation with dense-disperse waves at 50 Hz and 10 V will be applied on the abdominal points. The bodily needles will be retained for 30 minutes. For subjects assigned to the control group, Streitberger's non-invasive acupuncture needles will be applied to serve as the sham control at the same acupoints with the same stimulation modality, except that the needles are only adhered to the skin instead of inserted. The duration of the treatment is 8 weeks with two sessions per week, and the follow-up period is 8 weeks. The primary outcome is the change in body weight before and after treatment. The secondary outcomes include changes in body mass index, waist circumference, hip circumference, and body fat percentage during the treatment and follow-up period. Discussion: The study will compare the efficacy and safety of acupuncture with sham acupuncture on weight control, in the hope of obtaining evidence for utilizing acupuncture for body weight control.
C1 [Zhong, Linda L. D.; Kun, Wai; Lam, Tsz Fung; Zhang, Shi Ping; Yang, Jun Jun; Bian, Zhao Xiang] Hong Kong Baptist Univ, Hong Kong Chinese Med Study Ctr, AAB 105, Kowloon, Hong Kong, Peoples R China.
   [Zhong, Linda L. D.; Kun, Wai; Lam, Tsz Fung; Zhang, Shi Ping; Bian, Zhao Xiang] Hong Kong Baptist Univ, Sch Chinese Med, 3-F,Jockey Club Sch Chinese Med Bldg, Kowloon, Hong Kong, Peoples R China.
   [Ziea, Tat Chi; Ng, Bacon] Hong Kong Hosp Author, Chinese Med Dept, Kowloon, Hong Kong, Peoples R China.
C3 Hong Kong Baptist University; Hong Kong Baptist University
RP Bian, ZX (corresponding author), Hong Kong Baptist Univ, Hong Kong Chinese Med Study Ctr, AAB 105, Kowloon, Hong Kong, Peoples R China.; Bian, ZX (corresponding author), Hong Kong Baptist Univ, Sch Chinese Med, 3-F,Jockey Club Sch Chinese Med Bldg, Kowloon, Hong Kong, Peoples R China.
EM bzxiang@hkbu.edu.hk
FU Hong Kong Hospital Authority Research Project: Acupuncture for Body Weight Control: A Pilot Randomized Controlled Trial [HA 33-14-112-542-130]
CR Alexandre Leo, 2014, WORLD J GASTROINTEST PATHOPHYSIOL, V5, P534, DOI 10.4291/wjgp.v5.i4.534
   Unknown -, 2004, CHIN J CLIN REHAB, V0, P0
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   Chan EW, 2013, OBES REV, V14, P383, DOI 10.1111/obr.12015
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NR 20
TC 13
Z9 18
U1 1
U2 34
PU BIOMED CENTRAL LTD
PI LONDON
PA 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND
SN 1745-6215
EI 
J9 TRIALS
JI Trials
PD JUL 25
PY 2016
VL 17
IS 
BP 
EP 
DI 10.1186/s13063-016-1458-2
PG 7
WC Medicine, Research & Experimental
SC Research & Experimental Medicine
GA DR7UH
UT WOS:000380104700003
PM 27457720
DA 2026-01-16
ER

PT J
AU Gruenbaum, SE
   Meng, L
   Bilotta, F
AF Gruenbaum, Shaun E
   Meng, Lingzhong
   Bilotta, Federico
TI Recent trends in the anesthetic management of craniotomy for supratentorial tumor
SO Current opinion in anaesthesiology
LA English
DT Review
AB PURPOSE OF REVIEW: The article reviews the recent evidence on the anesthetic  management of patients undergoing craniotomy for supratentorial tumor resection.  RECENT FINDINGS: A rapid recovery of neurological function after craniotomy for  supratentorial tumor allows for the prompt diagnosis of intracranial  complications and possibly an early hospital discharge. Intraoperative esmolol  infusion was shown to reduce the anesthetic requirements, and may facilitate a  more rapid recovery of neurological function. Outpatient craniotomy for  supratentorial tumor resection has been associated with several clinical and  economic benefits, but has not gained widespread use because of skepticism and  medical-legal concerns. Awake craniotomy is associated with advantageous outcomes  compared with surgery under general anesthesia, and is regarded as the standard  of care for tumors that reside in or in close proximity to the eloquent brain.  Recent studies have demonstrated that intraoperative electroacupuncture,  dexmedetomidine, pregabalin, and lidocaine may facilitate postcraniotomy pain  management. The use of volatile anesthetic agents in cancer surgery is associated  with a worse survival compared with intravenous anesthetics, possibly by  hindering immunologic defenses against cancer cells. SUMMARY: Recent evidence has  yielded valuable information regarding anesthetic management of patients  undergoing supratentorial tumor craniotomy. Despite a plethora of studies that  compare short-term outcomes using different anesthetic and analgesic regimens,  randomized controlled trials that examine the long-term outcomes (i.e.,  neurocognitive function, quality of life, tumor recurrence, and survival) that  are of particular interest to patients are needed.
C1 aDepartment of Anesthesiology, Yale University School of Medicine, New Haven, Connecticut, USA bDepartment of Anesthesiology, Critical Care and Pain Medicine,'Sapienza' University of Rome, Rome, Italy.
NR 0
TC 0
SN 1473-650
EI 
J9 Curr Opin Anaesthesiol
PD JUN 11
PY 2016
VL 29
IS 5
BP 552
EP 7
DI 10.1097/ACO.0000000000000365
PG -545
WC Analgesics; therapeutic use; Anesthesia; adverse effects; Anesthetics, Inhalation; administration & dosage; Cognition; drug effects; Craniotomy; adverse effects; Electroacupuncture; Humans; Neoplasm Recurrence, Local; mortality; Pain Management; methods; Pain, Postoperative; therapy; Perioperative Care; methods; Quality of Life; Supratentorial Neoplasms; mortality; Treatment Outcome
UT PubMed:27285727
PM 27285727
DA 2016-06-11
ER

PT J
AU Nielsen, S
   Campbell, G
   Peacock, A
   Smith, K
   Bruno, R
   Hall, W
   Cohen, M
   Degenhardt, L
AF Nielsen, Suzanne
   Campbell, Gabrielle
   Peacock, Amy
   Smith, Kimberly
   Bruno, Raimondo
   Hall, Wayne
   Cohen, Milton
   Degenhardt, Louisa
TI Health service utilisation by people living with chronic non-cancer pain: findings from the Pain and Opioids IN Treatment (POINT) study
SO AUSTRALIAN HEALTH REVIEW
LA English
DT Article
DE acupuncture; barriers; chiropractor; complementary and alternative medicines
ID low-back-pain; efficacy; therapy; questionnaire; complementary; metaanalysis; guidelines; veterans; medicine; barriers
AB Objective. The aims of the present study were to describe the use, and barriers to the use, of non-medication pain therapies and to identify the demographic and clinical correlates of different non-opioid pain treatments. Methods. The study was performed on a cohort (n = 1514) of people prescribed pharmaceutical opioids for chronic noncancer pain (CNCP). Participants reported lifetime and past month use of healthcare services, mental and physical health, pain characteristics, current oral morphine equivalent daily doses and financial and access barriers to healthcare services. Results. Participants reported the use of non-opioid pain treatments, both before and after commencing opioid therapy. Services accessed most in the past month were complementary and alternative medicines (CAMs; 41%), physiotherapy (16%) and medical and/or pain specialists (15%). Higher opioid dose was associated with increased financial and access barriers to non-opioid treatment. Multivariate analyses indicated being younger, female and having private health insurance were the factors most commonly associated with accessing non-opioid treatments. Conclusions. Patients on long-term opioid therapy report using multiple types of pain treatments. High rates of CAM use are concerning given limited evidence of efficacy for some therapies and the low-income status of most people with CNCP. Financial and insurance barriers highlight the importance of considering how different types of treatments are paid for and subsidised.
C1 [Nielsen, Suzanne; Campbell, Gabrielle; Smith, Kimberly; Bruno, Raimondo; Degenhardt, Louisa] UNSW, Natl Drug & Alcohol Res Ctr, 22-32 King St, Randwick, NSW 2031, Australia.
   [Nielsen, Suzanne] South East Sydney Local Hlth Dist SESLHD Drug & A, 591-623 S Dowling St, Surry Hills, NSW 2010, Australia.
   [Peacock, Amy; Bruno, Raimondo] Univ Tasmania, Sch Med, Private Bag 30, Hobart, Tas 7001, Australia.
   [Hall, Wayne] Univ Queensland, Ctr Youth Subst Abuse Res, Brisbane, Qld 4072, Australia.
   [Cohen, Milton] UNSW Med, St Vincents Hosp, St Vincents Clin Sch, Level 5 deLacy Bldg,Victoria St, Darlinghurst, NSW 2010, Australia.
   [Degenhardt, Louisa] Univ Melbourne, Sch Populat & Global Hlth, Level 4,207 Bouverie St, Melbourne, Vic 3010, Australia.
C3 University of New South Wales Sydney; University of Tasmania; University of Queensland; St Vincent's Clinic; NSW Health; St Vincents Hospital Sydney; University of Melbourne
RP Nielsen, S (corresponding author), UNSW, Natl Drug & Alcohol Res Ctr, 22-32 King St, Randwick, NSW 2031, Australia.; Nielsen, S (corresponding author), South East Sydney Local Hlth Dist SESLHD Drug & A, 591-623 S Dowling St, Surry Hills, NSW 2010, Australia.
EM suzanne.nielsen@unsw.edu.au; g.campbell@unsw.edu.au; Amy.Peacock@utas.edu.au; kimberley.smith@unsw.edu.au; Raimondo.Bruno@utas.edu.au; w.hall@uq.edu.au; M.Cohen@unsw.edu.au; l.degenhardt@unsw.edu.au
FU Australian National Health and Medical Research Council (NHMRC) [1022522]; NHMRC [1013803, 1041472, 569738]; Australian Government under the Substance Misuse Prevention and Service Improvements Grant Fund; National Health and Medical Research Council (NHMRC) [569738, 1022522] Funding Source: National Health and Medical Research Council (NHMRC)
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NR 43
TC 10
Z9 13
U1 0
U2 9
PU CSIRO PUBLISHING
PI CLAYTON
PA UNIPARK, BLDG 1, LEVEL 1, 195 WELLINGTON RD, LOCKED BAG 10, CLAYTON, VIC 3168, AUSTRALIA
SN 0156-5788
EI 1449-8944
J9 AUST HEALTH REV
JI Aust. Health Rev.
PD JUN 15
PY 2016
VL 40
IS 5
BP 490
EP 499
DI 10.1071/AH15047
PG 10
WC Health Care Sciences & Services; Health Policy & Services
SC Health Care Sciences & Services
GA DZ6YB
UT WOS:000386007600003
PM 26599263
DA 2026-01-16
ER

PT J
AU Hu, CQ
   Zhang, HB
   Wu, WY
   Yu, WQ
   Li, Y
   Bai, JP
   Luo, BH
   Li, SP
AF Hu, Caiqiong
   Zhang, Haibo
   Wu, Wanyin
   Yu, Weiqing
   Li, Yong
   Bai, Jianping
   Luo, Baohua
   Li, Shuping
TI Acupuncture for Pain Management in Cancer: A Systematic Review and Meta-Analysis
SO EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
LA English
DT Review
ID electroacupuncture; expression
AB Objective. To evaluate the effectiveness and safety of acupuncture for cancer-related pain. Methods. Asystematic review of literatures published from database inception to February 2015 was conducted in eight databases. RCTs involving acupuncture for treatment of cancer-related pain were identified. Two researchers independently performed article selection, data extraction, and quality assessment of data. Results. 1,639 participants in twenty RCTs were analyzed. All selected RCTs were associated with high risk of bias. Meta-analysis indicated that acupuncture alone did not have superior pain-relieving effects as compared with conventional drug therapy. However, as compared with the drug therapy alone, acupuncture plus drug therapy resulted in increased pain remission rate, shorter onset time of pain relief, longer pain-free duration, and better quality of life without serious adverse effects. However, GRADE analysis revealed that the quality of all outcomes about acupuncture plus drug therapy was very low. Conclusions. Acupuncture plus drug therapy is more effective than conventional drug therapy alone for cancer-related pain. However, multicenter high-quality RCTs with larger sample sizes are needed to provide stronger evidence for the effectiveness of acupuncture in cancer-related pain due to the low data quality of the studies included in the current meta-analysis.
C1 [Hu, Caiqiong; Yu, Weiqing; Luo, Baohua; Li, Shuping] Guangzhou Univ Chinese Med, Sch Clin Med 2, Guangzhou 510405, Guangdong, Peoples R China.
   [Zhang, Haibo; Wu, Wanyin; Li, Yong; Bai, Jianping] Guangdong Prov Hosp Chinese Med, Dept Oncol, Guangzhou 510120, Guangdong, Peoples R China.
C3 Guangzhou University of Chinese Medicine; Guangzhou University of Chinese Medicine
RP Zhang, HB (corresponding author), Guangdong Prov Hosp Chinese Med, Dept Oncol, Guangzhou 510120, Guangdong, Peoples R China.
EM haibozh@aliyun.com
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NR 47
TC 64
Z9 71
U1 1
U2 25
PU HINDAWI LTD
PI LONDON
PA ADAM HOUSE, 3RD FLR, 1 FITZROY SQ, LONDON, W1T 5HF, ENGLAND
SN 1741-427X
EI 1741-4288
J9 EVID-BASED COMPL ALT
JI Evid.-based Complement Altern. Med.
PD JUN 15
PY 2016
VL 2016
IS 
BP 
EP 
DI 10.1155/2016/1720239
PG 13
WC Integrative & Complementary Medicine
SC Integrative & Complementary Medicine
GA DE5WM
UT WOS:000370703900001
PM 26977172
DA 2026-01-16
ER

PT J
AU Yang, GS
   Kim, HJ
   Griffith, KA
   Zhu, S
   Dorsey, SG
   Renn, CL
AF Yang, Gee Su
   Kim, Hee Jun
   Griffith, Kathleen A
   Zhu, Shijun
   Dorsey, Susan G
   Renn, Cynthia L
TI Interventions for the Treatment of Aromatase Inhibitor-Associated Arthralgia in
SO Cancer nursing
LA English
DT Journal Article
AB BACKGROUND: Aromatase inhibitors (AIs) have been established as successful  adjuvant therapy for breast cancer survivors. Unfortunately, nearly half of women  taking AIs report joint pain, AI-associated arthralgia (AIA). Aromatase  inhibitor-associated arthralgia often results in noncompliance, which could lead  to cancer recurrence. OBJECTIVE: The purpose of this study was to identify  current pain management of AIA and to evaluate the study quality and effects of  interventions. METHODS: Nineteen articles published from 2000 to August 2015 were  identified using PubMed, CINAHL, PsycINFO, Web of Science, and additional  records. Study quality was evaluated by the Quality Assessment Tool for  Quantitative Studies. Meta-analysis was used to obtain effect sizes of  interventions on pain and subgroups. RESULTS: Five types of interventions  emerged: pharmacological approaches, acupuncture, nutritional supplementation,  relaxation techniques, and physical exercise. Six studies were strong, 8 were  moderate, and 5 were weak in quality. The overall effect size of the  interventions on pain was large; pharmacological approaches, acupuncture, and  relaxation techniques showed moderate to large effects on pain, whereas  nutritional supplementation and physical exercise had no significant effects on  it. CONCLUSION: The evidence was based on a body of research with moderate study  quality. Although the overall effect of interventions is large, further  investigation into the influence of nutrition and physical exercise is needed to  better discern their potential for pain management. IMPLICATION FOR PRACTICE:  Oncology nurses may be able to implement such validated interventions as pain  management modalities to mitigate the symptoms so that breast cancer survivors  remain compliant with AIA therapy.
C1 Author Affiliations: Departments of Pain and Translational Symptom Science (Ms Yang and Drs Kim, Griffith, Dorsey, and Renn) and Organizational Systems andAdult Health (Dr Zhu), University of Maryland School of Nursing, Baltimore.
NR 0
TC 0
SN 1538-980
EI 
J9 Cancer Nurs
PD JUN 23
PY 2016
VL 40
IS 4
BP E26
EP E41
DI 10.1097/NCC.0000000000000409
PG 1
WC Aromatase Inhibitors; adverse effects; Arthralgia; chemically induced; Breast Neoplasms; drug therapy; Female; Humans; Randomized Controlled Trials as Topic; Survivors; Treatment Outcome
UT PubMed:27333128
PM 27333128
DA 2016-06-23
ER

PT J
AU Chen, J
   Zhang, Y
   Wang, P
   Wang, B
   Zhang, G
   Wang, X
AF Chen, Jia
   Zhang, Yunfeng
   Wang, Peiru
   Wang, Bo
   Zhang, Guolong
   Wang, Xiuli
TI Plum-blossom needling promoted PpIX fluorescence intensity from 5-aminolevulinic
SO Photodiagnosis and photodynamic therapy
LA English
DT Journal Article
DE Fractional ablative resurfacing; Photodynamic therapy; Photosensitizer; Plum-blossom needling; Topical drugs
AB BACKGROUND AND OBJECTIVES: Plum-blossom needling might enhance transdermal  penetration of topically applied drugs by creating vertical channels. The purpose  of this study was to evaluate drug delivery assisted by plum-blossom needling  comparing with CO2 laser ablative fractional resurfacing (AFR) using  5-aminolevulinic acid (5-ALA), a porphyrin precursor, as a test drug. MATERIALS  AND METHODS: Ex vivo porcine skin was treated with plum-blossom needle(HWATO,  Suzhou medical supplies factory Co., Ltd. China) or CO2 laser AFR before topical  application of 20% 5-ALA(Sigma-Aldrich, Co., USA)cream, placebo cream and no  cream. ALA-induced porphyrin fluorescence was measured by fluorescence microscopy  at skin depths down to 1800μm. Needling was done by tapping the skin vertically  from 5cm high above quickly. AFR was performed with a 10.6μm wavelength prototype  CO2 laser, using stacked single pulses of 3 millisecond and 91.6mJ per pulse.  Plum-blossom needling after ALA application was also done. Fluorescence intensity  on lesion surface was examined by curalux spectrum analyzer (Laser Institute of  Munich University, Germany) and VAS pain score was recorded in a randomized  split-lesion clinical trial including 6 patients, 8 actinic keratosis lesions.  RESULTS: AFR created regular cone-shaped channels surrounded by a 70μm thin layer  of thermally coagulated dermis, respectively. The cone is approximately 200μm in  diameter at the opening and 1850μm in depth. Plum-blossom needle created  irregular cone-shaped channels of approximately 180μm in diameter at the opening  and it always drags a tail-which was shaped from the closed deeper channels.  There was no porphyrin fluorescence in placebo cream or untreated skin sites.  Plum-blossom needling followed by ALA application enhanced drug delivery with  significantly higher porphyrin fluorescence at the edge of hole (P<0.005) and  100μm far from the hole (P=0.000) versus AFR followed by ALA application at skin  depths of 120 and 500μm. Needling after ALA application presented higher  porphyrin fluorescence at the edge of hole at skin depths of 120μm (P<0.005) and  lower porphyrin fluorescence at 1000μm deep hole edge, and 100μm far from the  hole at 120μm, 500μm and 1000μm depths versus AFR followed by ALA application  (P<0.005). Skin massage after ALA application did not affect ALA-induced  porphyrin fluorescence after pretreatment of plum-blossom needling or AFR. ALA  application after plum-blossom needling was better than before plum-blossom  needling. The clinical trial showed that the surface fluorescence intensity was  stronger in needle-pretreated-lesion than in laser-pretreated-lesion. While the  VAS pain score between needle treatment and laser treatment was almost the same.  CONCLUSIONS: Plum-blossom needling facilitates delivery of topical ALA into the  dermis. It may help ALA to diffuse a little more broadly than AFR does in  superficial dermis and obtain similar clinical effect with a much lower cost.  Plum-blossom needling treatment appears to be a clinically practical and  economical means for enhancing transdermal delivery of ALA, a photodynamic  therapy drug, and presumably many other topical skin medications.
C1 Institute of Photomedicine, Shanghai Skin Disease Hospital, Tongji University, Shanghai, PR China. 
   Institute of Photomedicine, Shanghai Skin Disease Hospital, Tongji University, Shanghai, PR China. 
   Institute of Photomedicine, Shanghai Skin Disease Hospital, Tongji University, Shanghai, PR China. 
   Institute of Photomedicine, Shanghai Skin Disease Hospital, Tongji University, Shanghai, PR China. 
   Institute of Photomedicine, Shanghai Skin Disease Hospital, Tongji University, Shanghai, PR China. 
   Institute of Photomedicine, Shanghai Skin Disease Hospital, Tongji University, Shanghai, PR China.
EM Wangxiuli20150315@163.com
NR 0
TC 0
SN 1873-159
EI 
J9 Photodiagnosis Photodyn Ther
PD JUL 5
PY 2016
VL 15
IS 
BP 182
EP 90
DI 10.1016/j.pdpdt.2016.06.012
PG -92
WC Acupuncture Therapy; instrumentation; Aged; Aminolevulinic Acid; pharmacokinetics; Animals; Female; Fluorescent Dyes; pharmacokinetics; Humans; In Vitro Techniques; Keratosis, Actinic; metabolism; Male; Microscopy, Fluorescence; methods; Middle Aged; Photosensitizing Agents; pharmacokinetics; Protoporphyrins; pharmacokinetics; Skin; metabolism; Skin Absorption; physiology; Swine
UT PubMed:27375183
PM 27375183
DA 2016-07-05
ER

PT J
AU Deganello, A
   Battat, N
   Muratori, E
   Cristofaro, G
   Buongiorno, A
   Mannelli, G
   Picconi, M
   Giachetti, R
   Borsotti, G
   Gallo, O
AF Deganello, Alberto
   Battat, Nir
   Muratori, Enrico
   Cristofaro, Glauco
   Buongiorno, Ana
   Mannelli, Giuditta
   Picconi, Mario
   Giachetti, Rita
   Borsotti, Giulia
   Gallo, Oreste
TI Acupuncture in shoulder pain and functional impairment after neck dissection: A prospective randomized pilot study
SO LARYNGOSCOPE
LA English
DT Article
DE Acupuncture; neck dissection; neck disability; neck pain; shoulder syndrome; shoulder dysfunction
ID n0 laryngeal-cancer; healthy-subjects; trial; analgesia; brain
AB Objectives/HypothesisThe efficacy of conventional physiotherapy and antiinflammatory/analgesic drugs in the management of shoulder pain and functional disability following neck dissection is often disappointing. Acupuncture is a safe and well-tolerated method. We report the results regarding our pilot trial of acupuncture versus conventional care in the management of postoperative shoulder pain and dysfunction after neck dissection. Study DesignPilot study. MethodsPatients at a tertiary university center with chronic pain or dysfunction attributed to neck dissection were randomly assigned to either weekly acupuncture or usual care (eg., physical therapy, analgesia, and/or antiinflammatory drugs) for 5 consecutive weeks. The Constant-Murley score, a composite measure of pain, function, and activities of daily living, was the primary outcome measure. As secondary end point, The Neck Dissection Impairment Index (NDII) was used to quantify site-specific, self-reported quality of life (QOL). ResultsAfter randomization, 48 patients completed the study (23 and 25 patients on acupuncture and control arms, respectively). Constant-Murley scores improved more in the acupuncture group (gain difference between groups 13.6, P < 0.01), a statistically significant improvement in site-specific QOL was also recorded at NDII (gain difference between groups 11.5, P < 0.01). ConclusionAcupuncture is safe and effective; it should be introduced and offered to patients suffering from neck pain and dysfunction related to neck dissection.
C1 [Deganello, Alberto; Battat, Nir; Muratori, Enrico; Cristofaro, Glauco; Buongiorno, Ana; Mannelli, Giuditta; Gallo, Oreste] Univ Florence, Clin Otolaryngol Head & Neck Surg 1, Dept Surg & Translat Med, Largo Brambilla 3, I-50134 Florence, Italy.
   [Giachetti, Rita; Borsotti, Giulia] Univ Florence, Dept Anaesthesiol, Florence, Italy.
   [Picconi, Mario] Sinergie Ctr, Acupuncture, Florence, Italy.
C3 University of Florence; University of Florence
RP Deganello, A (corresponding author), Univ Florence, Clin Otolaryngol Head & Neck Surg 1, Dept Surg & Translat Med, Largo Brambilla 3, I-50134 Florence, Italy.
EM adeganello@hotmail.com
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NR 29
TC 14
Z9 20
U1 0
U2 33
PU WILEY-BLACKWELL
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 0023-852X
EI 1531-4995
J9 LARYNGOSCOPE
JI Laryngoscope
PD AUG 15
PY 2016
VL 126
IS 8
BP 1790
EP 1795
DI 10.1002/lary.25921
PG 6
WC Medicine, Research & Experimental; Otorhinolaryngology
SC Research & Experimental Medicine; Otorhinolaryngology
GA DR6AY
UT WOS:000379984700017
PM 27010596
DA 2026-01-16
ER

PT J
AU Kim, W
   Kim, MJ
   Go, D
   Min, BI
   Na, HS
   Kim, SK
AF Kim, Woojin
   Kim, Min Joon
   Go, Donghyun
   Min, Byung-Il
   Na, Heung Sik
   Kim, Sun Kwang
TI Combined Effects of Bee Venom Acupuncture and Morphine on Oxaliplatin-Induced
SO Toxins
LA English
DT Journal Article
DE bee venom acupuncture; chemotherapy induced neuropathic pain; morphine; oxaliplatin
AB Oxaliplatin, a chemotherapeutic drug for colorectal cancer, induces severe  peripheral neuropathy. Bee venom acupuncture (BVA) has been used to attenuate  pain, and its effect is known to be mediated by spinal noradrenergic and  serotonergic receptors. Morphine is a well-known opioid used to treat different  types of pain. Here, we investigated whether treatment with a combination of  these two agents has an additive effect on oxaliplatin-induced neuropathic pain  in mice. To assess cold and mechanical allodynia, acetone and von Frey filament  tests were used, respectively. Significant allodynia signs were observed three  days after an oxaliplatin injection (6 mg/kg, i.p.). BVA (0.25, 1, and 2.5 mg/kg,  s.c., ST36) or morphine (0.5, 2, and 5 mg/kg, i.p.) alone showed dose-dependent  anti-allodynic effects. The combination of BVA and morphine at intermediate doses  showed a greater and longer effect than either BVA or morphine alone at the  highest dose. Intrathecal pretreatment with the opioidergic (naloxone, 20 μg) or  5-HT3 (MDL-72222, 15 μg) receptor antagonist, but not with α2 adrenergic  (idazoxan, 10 μg) receptor antagonist, blocked this additive effect. Therefore,  we suggest that the combination effect of BVA and morphine is mediated by spinal  opioidergic and 5-HT3 receptors and this combination has a robust and enduring  analgesic action against oxaliplatin-induced neuropathic pain.
C1 Department of Physiology, College of Korean Medicine, Kyung Hee University, 26 Kyungheedae-ro, Dongdamoon-gu, Seoul 02447, Korea. thasnow@gmail.com.
   Department of East-West Medicine, Graduate School, Kyung Hee University, 26 
   Department of East-West Medicine, Graduate School, Kyung Hee University, 26 Kyungheedae-ro, Dongdamoon-gu, Seoul 02447, Korea. junesnest@naver.com.
   Department of East-West Medicine, Graduate School, Kyung Hee University, 26 Kyungheedae-ro, Dongdamoon-gu, Seoul 02447, Korea. drum2r@daum.net.
   Yeongju Municipal Hospital, 697 Jangan-ro, Anjeong-myeon, Gyeongsangbuk-do, Yeongju-si 36051, Korea. mbi@khu.ac.kr.
   Department of Physiology, College of Medicine, Korea University, Anam-dong 5-ga, Seongbuk-gu, Seoul 02842, Korea. hsna@korea.ac.kr.
   Department of Physiology, College of Korean Medicine, Kyung Hee University, 26 Kyungheedae-ro, Dongdamoon-gu, Seoul 02447, Korea. skkim77@khu.ac.kr.
   Department of East-West Medicine, Graduate School, Kyung Hee University, 26
NR 0
TC 0
SN 2072-665
EI 
J9 Toxins (Basel)
PD JAN 26
PY 2016
VL 8
IS 2
BP 33
EP 33
DI 10.3390/toxins8020033
PG 0
WC Acupuncture; Analgesics; therapeutic use; Animals; Antineoplastic Agents; adverse effects; Bee Venoms; therapeutic use; Cold Temperature; Combined Modality Therapy; Hyperalgesia; chemically induced; Male; Mice, Inbred C57BL; Morphine; therapeutic use; Naloxone; pharmacology; Narcotic Antagonists; pharmacology; Neuralgia; chemically induced; Organoplatinum Compounds; adverse effects; Oxaliplatin; Physical Stimulation; Receptors, Opioid; metabolism; Receptors, Serotonin, 5-HT3; metabolism; Serotonin 5-HT3 Receptor Antagonists; pharmacology; Tropanes; pharmacology
UT PubMed:26805884
PM 26805884
DA 2016-01-26
ER

PT J
AU Pugh, SL
   Wyatt, G
   Wong, RK
   Sagar, SM
   Yueh, B
   Singh, AK
   Yao, M
   Nguyen-Tan, PF
   Yom, SS
   Cardinale, FS
   Sultanem, K
   Hodson, DI
   Krempl, GA
   Chavez, A
   Yeh, AM
   Bruner, DW
AF Pugh, Stephanie L
   Wyatt, Gwen
   Wong, Raimond K W
   Sagar, Stephen M
   Yueh, Bevan
   Singh, Anurag K
   Yao, Min
   Nguyen-Tan, Phuc Felix
   Yom, Sue S
   Cardinale, Francis S
   Sultanem, Khalil
   Hodson, D Ian
   Krempl, Greg A
   Chavez, Ariel
   Yeh, Alexander M
   Bruner, Deborah W
TI Exploratory Factor Analysis of NRG Oncology's University of Washington Quality of
SO Journal of pain and symptom management
LA English
DT Journal Article
DE Quality of life; factor analysis; xerostomia
AB CONTEXT: The 15-item University of Washington Quality of Life  questionnaire-Radiation Therapy Oncology Group (RTOG) modification (UW-QOL-RTOG  modification) has been used in several trials of head and neck cancer conducted  by NRG Oncology such as RTOG 9709, RTOG 9901, RTOG 0244, and RTOG 0537.  OBJECTIVES: This study is an exploratory factor analysis (EFA) to establish  validity and reliability of the instrument subscales. METHODS: EFA on the  UW-QOL-RTOG modification was conducted using baseline data from NRG Oncology's  RTOG 0537, a trial of acupuncture-like transcutaneous electrical nerve  stimulation in treating radiation-induced xerostomia. Cronbach α coefficient was  calculated to measure reliability; correlation with the University of Michigan  Xerostomia Related Quality of Life Scale was used to evaluate concurrent  validity; and correlations between consecutive time points were used to assess  test-retest reliability. RESULTS: The 15-item EFA of the modified tool resulted  in 11 items split into four factors: mucus, eating, pain, and activities.  Cronbach α ranged from 0.71 to 0.93 for the factors and total score, consisting  of all 11 items. There were strong correlations (ρ ≥ 0.60) between consecutive  time points and between total score and the Xerostomia Related Quality of Life  Scale total score (ρ > 0.65). CONCLUSION: The UW-QOL-RTOG modification is a valid  tool that can be used to assess symptom burden of head and neck cancer patients  receiving radiation therapy or those who have recently completed radiation. The  modified tool has acceptable reliability, concurrent validity, and test-retest  reliability in this patient population, as well as the advantage of having being  shortened from 15 to 11 items.
C1 NRG Oncology Statistics and Data Management Center, Philadelphia, Pennsylvania, USA. 
   Michigan State University, East Lansing, Michigan, USA.
   Juravinski Cancer Centre, McMaster University, Hamilton, Ontario, Canada.
   Juravinski Cancer Centre, McMaster University, Hamilton, Ontario, Canada.
   University of Minnesota/Masonic Cancer Center, Minneapolis, Minnesota, USA.
   Roswell Park Cancer Institute, Buffalo, New York, USA.
   Case Western Reserve University, Cleveland, Ohio, USA.
   CHUM-Hôpital Notre-Dame, Montréal, Quebec, Canada.
   UCSF Medical Center, San Francisco, California, USA.
   Yale University, New Haven, Connecticut, USA.
   McGill University, Montréal, Quebec, Canada.
   Juravinski Cancer Centre, McMaster University, Hamilton, Ontario, Canada.
   University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.
   John H. Stroger Jr. Hospital of Cook County, Chicago, Illinois, USA.
   Indiana University Hospital/Melvin and Bren Simon Cancer Center, Indianapolis, Indiana, USA.
   Emory University/Winship Cancer Institute, Atlanta, Georgia, USA.
EM pughs@nrgoncology.org
NR 0
TC 0
SN 1873-651
EI 0885-392
J9 J Pain Symptom Manage
PD DEC 3
PY 2016
VL 53
IS 1
BP 139
EP 145.e2
DI 10.1016/j.jpainsymman.2016.11.002
PG 1
WC Activities of Daily Living; psychology; Aged; Eating; psychology; Factor Analysis, Statistical; Female; Head and Neck Neoplasms; complications; Humans; Male; Middle Aged; Pain; etiology; Quality of Life; psychology; Surveys and Questionnaires
UT PubMed:27899312
PM 27899312
DA 2016-12-03
ER

PT J
AU Medeiros, LF
   Caumo, W
   Dussán-Sarria, J
   Deitos, A
   Brietzke, A
   Laste, G
   Campos-Carraro, C
   de Souza, A
   Scarabelot, VL
   Cioato, SG
   Vercelino, R
   de Castro, AL
   Sander, A
   Belló-Klein, A
   Fregni, F
   Torres, ILS
AF Medeiros, Liciane F.
   Caumo, Wolnei
   Dussan-Sarria, Jairo
   Deitos, Alicia
   Brietzke, Aline
   Laste, Gabriela
   Campos-Carraro, Cristina
   de Souza, Andressa
   Scarabelot, Vanessa L.
   Cioato, Stefania G.
   Vercelino, Rafael
   de Castro, Alexandre L.
   Sander, Alex
   Bello-Klein, Adriane
   Fregni, Felipe
   Torres, Iraci L. S.
TI Effect of Deep Intramuscular Stimulation and Transcranial Magnetic Stimulation on Neurophysiological Biomarkers in Chronic Myofascial Pain Syndrome
SO PAIN MEDICINE
LA English
DT Article
DE Myofascial Pain; BDNF; Oxidative Parameters
ID neurotrophic factor bdnf; tumor-necrosis-factor; central sensitization; electrical-stimulation; motor system; serum-levels; brain; cortex; acupuncture; stress
AB Objective. The aim was to assess the neuromodulation techniques effects (repetitive transcranial magnetic stimulation [rTMS] and deep intramuscular stimulation therapy [DIMST]) on pain intensity, peripheral, and neurophysiological biomarkers chronic myofascial pain syndrome (MPS) patients. Design. Randomized, double blind, factorial design, and controlled placebo-sham clinical trial. Setting. Clinical trial in the Laboratory of Pain and Neuromodulation at Hospital de Clinicas de Porto Alegre (NCT02381171). Subjects. We recruited women aged between 19- and 75-year old, with MPS diagnosis. Methods. Patients were randomized into four groups: rTMS + DIMST, rTMS + sham-DIMST, sham-rTMS + DIMST, sham-rTMS + sham-DIMST; and received 10 sessions for 20 minutes each one (rTMS and DIMST). Pain was assessed by visual analogue scale (VAS); neurophysiological parameters were assessed by transcranial magnetic stimulation; biochemical parameters were: BDNF, S100 beta, lactate dehydrogenase, inflammatory (TNF-alpha, IL6, and IL10), and oxidative stress parameters. Results. We observed the pain relief assessed by VAS immediately assessed before and after the intervention (P < 0.05, F-(1,F-3)= 3.494 and F-(1,F-3)= 4.656, respectively); in the sham-rTMS + DIMST group and both three active groups in relation to sham-rTMS + sham-DIMST group, respectively. There was an increase in the MEP after rTMS + sham-DIMST (P < 0.05). However, there was no change in all-peripheral parameters analyzed across the treatment (P > 0.05). Conclusion. Our findings add additional evidence about rTMS and DIMST in relieving pain in MPS patients without synergistic effect. No peripheral biomarkers reflected the analgesic effect of both techniques; including those related to cellular damage. Additionally, one neurophysiological parameter (increased MEP amplitude) needs to be investigated.
C1 [Medeiros, Liciane F.; Campos-Carraro, Cristina; Scarabelot, Vanessa L.; de Castro, Alexandre L.; Sander, Alex; Bello-Klein, Adriane; Torres, Iraci L. S.] Univ Fed Rio Grande do Sul, Inst Basic Hlth Sci, Postgrad Program Biol Sci, Rua Sarmento Leite,500 Sala 202, BR-90050170 Porto Alegre, RS, Brazil.
   [Medeiros, Liciane F.; Caumo, Wolnei; Dussan-Sarria, Jairo; Deitos, Alicia; Brietzke, Aline; Laste, Gabriela; de Souza, Andressa; Vercelino, Rafael; Torres, Iraci L. S.] HCPA, Lab Pain & Neuromodulat, Porto Alegre, RS, Brazil.
   [Caumo, Wolnei; Dussan-Sarria, Jairo; Deitos, Alicia; Brietzke, Aline; Laste, Gabriela; de Souza, Andressa; Cioato, Stefania G.; Vercelino, Rafael; Torres, Iraci L. S.] Univ Fed Rio Grande do Sul, Sch Med, Postgrad Program Med Sci, Rua Sarmento Leite,500 Sala 202, BR-90050170 Porto Alegre, RS, Brazil.
   [Caumo, Wolnei; Cioato, Stefania G.; Fregni, Felipe; Torres, Iraci L. S.] Univ Fed Rio Grande do Sul, Inst Basic Hlth Sci, Dept Pharmacol, Rua Sarmento Leite,500 Sala 202, BR-90050170 Porto Alegre, RS, Brazil.
   [Fregni, Felipe] Harvard Univ, Sch Med, Dept Phys Med & Rehabil, Boston, MA USA.
C3 Universidade Federal do Rio Grande do Sul; Universidade Federal do Rio Grande do Sul; Universidade Federal do Rio Grande do Sul; Harvard University; Harvard Medical School
RP Torres, ILS (corresponding author), Univ Fed Rio Grande do Sul, ICBS, Dept Farmacol, Rua Sarmento Leite,500 Sala 202, BR-90050170 Porto Alegre, RS, Brazil.
EM iracitorres@gmail.com
FU National Council for Scientific and Technological Development-CNPq; Graduate Research Group (GPPG) of Hospital de Clinicas de Porto Alegre [100196, 100276]; Coordination for the Improvement of Higher Education Personnel-CAPES; International Cooperation Program-CAPES [023/11]
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NR 98
TC 24
Z9 27
U1 0
U2 12
PU OXFORD UNIV PRESS
PI OXFORD
PA GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND
SN 1526-2375
EI 1526-4637
J9 PAIN MED
JI Pain Med.
PD JAN 15
PY 2016
VL 17
IS 1
BP 122
EP 135
DI 10.1111/pme.12919
PG 14
WC Anesthesiology; Medicine, General & Internal
SC Anesthesiology; General & Internal Medicine
GA DI8DD
UT WOS:000373730500016
PM 26408420
DA 2026-01-16
ER

PT J
AU Yeo, JH
   Yoon, SY
   Kwon, SK
   Kim, SJ
   Lee, JH
   Beitz, AJ
   Roh, DH
AF Yeo, Ji-Hee
   Yoon, Seo-Yeon
   Kwon, Soon-Keun
   Kim, Sol-Ji
   Lee, Jang-Hern
   Beitz, Alvin J.
   Roh, Dae-Hyun
TI Repetitive Acupuncture Point Treatment with Diluted Bee Venom Relieves Mechanical Allodynia and Restores Intraepidermal Nerve Fiber Loss in Oxaliplatin-Induced Neuropathic Mice
SO JOURNAL OF PAIN
LA English
DT Article
DE Bee venom; oxaliplatin; mechanical allodynia; intraepidermal nerve fibers; alpha-2 adrenoceptors
ID induced peripheral neuropathy; reduces nociceptive responses; mouse formalin test; acupoint stimulation; thermal hyperalgesia; colorectal-cancer; pain model; activation; paclitaxel; injection
AB The chemotherapeutic agent, oxaliplatin, produces a robust painful neuropathy that results in the loss of intraepidermal nerve fibers (IENFs). We have previously reported that an acupuncture point (acupoint) injection of diluted bee venom (DBV) produces a temporary antiallodynic effect in oxaliplatin-induced neuropathic mice. Herein we show a significant long-lasting antinociceptive effect of repetitive DBV acupoint treatment on oxaliplatin-induced mechanical allodynia and a significant reduction in the loss of IENFs. DBV (0.1 mg/kg, subcutaneous) was administered once a day for 18 days beginning on day 15 after oxaliplatin injection. Immunohistochemistry for IENF was performed on the glabrous skin of the hind paw footpad using the pan-neuronal marker, protein gene product 9.5. A temporary increase in mechanical threshold was observed 60 minutes after a single DBV injection into the Zusanli acupoint, and this effect was enhanced over time with repetitive DBV treatments. The basal mechanical threshold before daily DBV injection also increased from day, 7 after DBV injections, and peaked at day 14 after DBV treatment. Moreover, the oxaliplatininduced loss of IENFs was significantly reduced in mice treated repetitively with DBV. Repetitive pretreatment with the alpha-2 adrenoceptor antagonist, yohimbine, (5 mg/kg, subcutaneous) completely prevented the antiallodynic effects and the increase in IENFs observed in mice treated repetitively with DBV. Perspective: We showed that repetitive acupoint stimulation with DBV gradually and significantly reduced oxaliplatin-induced mechanical allodynia and restored the loss of IENFs in neuropathic mice via an alpha-2 adrenoceptor mechanism. Collectively, results of this study suggest that repetitive acupoint treatment with DBV can be a potential strategy for the management of chemotherapy induced neuropathy. (C) 2016 by the American Pain Society
C1 [Yeo, Ji-Hee; Kwon, Soon-Keun; Kim, Sol-Ji; Roh, Dae-Hyun] Kyung Hee Univ, Sch Dent, Dept Oral Physiol, Seoul 130701, South Korea.
   [Yeo, Ji-Hee; Kwon, Soon-Keun; Kim, Sol-Ji; Roh, Dae-Hyun] Kyung Hee Univ, Sch Dent, Res Ctr Tooth & Periodontal Tissue Regenerat, Seoul 130701, South Korea.
   [Yoon, Seo-Yeon] Seoul Natl Univ, Coll Nat Sci, Dent Res Inst, Dept Brain & Cognit Sci, Seoul 151742, South Korea.
   [Yoon, Seo-Yeon] Seoul Natl Univ, Sch Dent, Dept Neurobiol & Physiol, Seoul, South Korea.
   [Lee, Jang-Hern] Seoul Natl Univ, Coll Vet Med, Dept Vet Physiol, Seoul, South Korea.
   [Beitz, Alvin J.] Univ Minnesota, Coll Vet Med, Dept Vet & Biomed Sci, St Paul, MN 55108 USA.
C3 Kyung Hee University; Kyung Hee University; Seoul National University (SNU); Seoul National University (SNU); Seoul National University (SNU); University of Minnesota System; University of Minnesota Twin Cities
RP Roh, DH (corresponding author), Kyung Hee Univ, Sch Dent, Dept Oral Physiol, Seoul 130701, South Korea.
EM dhroh@khu.ac.kr
FU National Research Foundation of Korea (NRF) - Korea government (MSIP) [2012R1A5A2051385]
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NR 61
TC 27
Z9 31
U1 1
U2 15
PU CHURCHILL LIVINGSTONE
PI EDINBURGH
PA JOURNAL PRODUCTION DEPT, ROBERT STEVENSON HOUSE, 1-3 BAXTERS PLACE, LEITH WALK, EDINBURGH EH1 3AF, MIDLOTHIAN, SCOTLAND
SN 1526-5900
EI 
J9 J PAIN
JI J. Pain
PD MAR 15
PY 2016
VL 17
IS 3
BP 298
EP 309
DI 10.1016/j.jpain.2015.10.018
PG 12
WC Clinical Neurology; Neurosciences
SC Neurosciences & Neurology
GA DH3FH
UT WOS:000372672400003
PM 26604098
DA 2026-01-16
ER

PT J
AU Yeh, CH
   Chien, LC
   Lin, WC
   Bovbjerg, DH
   van Londen, GJ
AF Yeh, Chao Hsing
   Chien, Lung-Chang
   Lin, Wei-Chun
   Bovbjerg, Dana Howard
   van Londen, G. J.
TI Pilot Randomized Controlled Trial of Auricular Point Acupressure to Manage Symptom Clusters of Pain, Fatigue, and Disturbed Sleep in Breast Cancer Patients
SO CANCER NURSING
LA English
DT Article
DE Auricular point acupressure; Breast cancer patient; Symptom cluster
ID quality-of-life; behavioral-therapy; acupuncture; intervention; distress; oncology; radiotherapy; feasibility; prevalence; depression
AB Background: Current management for a symptom cluster of pain, fatigue, and disturbed sleep in breast cancer patients has limited effects. Objective: The purposes of this prospective, randomized controlled pilot study were to (1) assess the feasibility and tolerability of auricular point acupressure (APA) intervention to manage pain, fatigue, and sleep disturbance in breast cancer patients and (2) provide an initial appraisal of effect size as compared with a control intervention. Methods: Thirty-one participants were randomized into either an active APA group (n = 16) or a control APA group (n = 15), which included the sham APA treatment not related to the symptoms. All participants received the APA once a week for 4 weeks. Self-report measures were obtained at baseline, weekly during intervention, at end of intervention, and at a 1-month follow-up. Results: For the 4-week of APA treatment, the retention rate was 88% for the active APA group and 73% for the control APA group. After 4 weeks of APA, participants in the active APA treatment had reported a reduction of 71% in pain, 44% in fatigue, 31% in sleep disturbance, and 61% in interference with daily activities. The control APA group experienced some moderate reduction in these symptoms. Conclusion: Given that this was a pilot study with a small sample size, results must be interpreted with caution. Implications for Practice: Our results suggest that APA may provide an inexpensive and effective complementary approach for the management of symptom clusters for breast cancer patients, and further study is warranted.
C1 [Yeh, Chao Hsing; Lin, Wei-Chun] Univ Pittsburgh, Sch Nursing, Pittsburgh, PA 15261 USA.
   [Chien, Lung-Chang] Univ Texas San Antonio, Dept Biostat, San Antonio, TX USA.
   [Bovbjerg, Dana Howard] Univ Pittsburgh, Biobehav Oncol Program, Pittsburgh, PA USA.
   [van Londen, G. J.] Univ Pittsburgh, Dept Med, Med Ctr, Pittsburgh, PA USA.
C3 Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; University of Texas System; University of Texas at San Antonio; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh; Pennsylvania Commonwealth System of Higher Education (PCSHE); University of Pittsburgh
RP Yeh, CH (corresponding author), Univ Pittsburgh, Sch Nursing, Pittsburgh, PA 15261 USA.
EM yehc@pitt.edu
FU American Cancer Society [124638-PEP-13-237-01-PCSM]; National Institute on Aging [T32AG021885] Funding Source: NIH RePORTER
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NR 49
TC 74
Z9 95
U1 2
U2 56
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0162-220X
EI 1538-9804
J9 CANCER NURS
JI Cancer Nurs.
PD SEP-OCT 15
PY 2016
VL 39
IS 5
BP 402
EP 410
DI 10.1097/NCC.0000000000000303
PG 9
WC Oncology; Nursing
SC Oncology; Nursing
GA DW9LX
UT WOS:000383982600014
PM 26390073
DA 2026-01-16
ER

PT J
AU Haumann, J
   Geurts, JW
   van Kuijk, SMJ
   Kremer, B
   Joosten, EA
   van den Beuken-van Everdingen, MHJ
AF Haumann, J.
   Geurts, J. W.
   van Kuijk, S. M. J.
   Kremer, B.
   Joosten, E. A.
   van den Beuken-van Everdingen, M. H. J.
TI Methadone is superior to fentanyl in treating neuropathic pain in patients with head-and-neck cancer
SO EUROPEAN JOURNAL OF CANCER
LA English
DT Article
DE Methadone; Fentanyl; Head-and-neck cancer; Cancer pain; NMDA receptor antagonist
ID clinical importance; hospital anxiety; oral methadone; morphine; validation; version; antagonists; rotation; ketamine; receptor
AB Background: Cancer pain is still inadequately treated in up to 60% of cancer patients. Based on the additional effect on the N-Methyl-D-Aspartate receptor, we expected that methadone (Met) could provide better pain relief than fentanyl (Fen) in cancer pain with a neuropathic pain component. Methods: A randomised controlled trial was performed with 52 strong opioids naive patients with head-and-neck cancer with substantial pain (pain Numerical Rating Scale [NRS] > 4) and a neuropathic pain component (Douleur Neuropathique [DN4] > 4). Twenty-six patients were treated with Met and 26 with Fen. Patients were evaluated at 1, 3 and 5 weeks. The primary outcomes were reduction in average pain, clinical success (defined as 50% average pain decrease) and reduction in pain interference. Secondary outcomes were global perceived effect (GPE) and side-effects. Findings: Reduction in NRS was higher with the use of Met at 1, 3 and 5 weeks (pain change 2.9, 3.1 and 3.1) compared to Fen (1.4, 1.7 and 2.0). This difference was significant at 1 (p = 0.011) and at 3 weeks (p = 0.03). Clinical success (> 50% improvement) was higher with Met at 1 week (15% versus 50%, p = 0.012). The change in pain interference, the GPE and side-effect profile were not significantly different between the groups. Interpretation: This is the first study to compare the effects of Met to Fen in cancer patients with a neuropathic pain component. Based on the results of this study, Met should be considered in the treatment of oncological pain with a neuropathic component. (C) 2016 Elsevier Ltd. All rights reserved.
C1 [Haumann, J.; Geurts, J. W.; Joosten, E. A.; van den Beuken-van Everdingen, M. H. J.] Maastricht Univ, Med Ctr, Univ Pain Ctr Maastricht UPCM, Dept Anesthesiol & Pain Management, Maastricht, Netherlands.
   [Haumann, J.] OLVG, Dept Anaesthesiol & Pain Management, Amsterdam, Netherlands.
   [van Kuijk, S. M. J.] Maastricht Univ, Med Ctr, Dept Clin Epidemiol & Med Technol Assessment, Maastricht, Netherlands.
   [Kremer, B.] Maastricht Univ, Med Ctr, Dept Otorhinolaryngol Head & Neck Surg, GROW Sch Oncol & Dev Biol, Maastricht, Netherlands.
   [Joosten, E. A.] Maastricht Univ, Sch Mental Hlth & Neurosci, Dept Translat Neurosci, Maastricht, Netherlands.
   [van den Beuken-van Everdingen, M. H. J.] Maastricht Univ, Med Ctr MUMC, Ctr Expertise Palliat Care, Maastricht, Netherlands.
C3 Maastricht University; Onze Lieve Vrouwe Gasthuis Hospital; Maastricht University; Maastricht University; Maastricht University; Maastricht University; Maastricht University Medical Centre (MUMC)
RP van den Beuken-van Everdingen, MHJ (corresponding author), MUMC, RVE Patient Zorg, POB 5800, NL-6202 AZ Maastricht, Netherlands.
EM m.vanden.beuken@mumc.nl
CR Benítez-Rosario MA, 2009, J PAIN SYMPTOM MANAG, V37, P1061, DOI 10.1016/j.jpainsymman.2008.05.016
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NR 46
TC 63
Z9 65
U1 0
U2 12
PU ELSEVIER SCI LTD
PI OXFORD
PA THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
SN 0959-8049
EI 1879-0852
J9 EUR J CANCER
JI Eur. J. Cancer
PD SEP 15
PY 2016
VL 65
IS 
BP 121
EP 129
DI 10.1016/j.ejca.2016.06.025
PG 9
WC Oncology
SC Oncology
GA DU5BP
UT WOS:000382227300014
PM 27494037
DA 2026-01-16
ER

PT J
AU Lau, CHY
   Wu, XY
   Chung, VCH
   Liu, X
   Hui, EP
   Cramer, H
   Lauche, R
   Wong, SYS
   Lau, AYL
   Sit, RST
   Ziea, ETC
   Ng, BFL
   Wu, JCY
AF Lau, Charlotte H. Y.
   Wu, Xinyin
   Chung, Vincent C. H.
   Liu, Xin
   Hui, Edwin P.
   Cramer, Holger
   Lauche, Romy
   Wong, Samuel Y. S.
   Lau, Alexander Y. L.
   Sit, Regina S. T.
   Ziea, Eric T. C.
   Ng, Bacon F. L.
   Wu, Justin C. Y.
TI Acupuncture and Related Therapies for Symptom Management in Palliative Cancer Care Systematic Review and Meta-Analysis
SO MEDICINE
LA English
DT Review
ID optimal search strategy; adverse events; fatigue; pain; hypogonadism; chemotherapy; survival; quality; burden
AB Available systematic reviews showed uncertainty on the effectiveness of using acupuncture and related therapies for palliative cancer care. The aim of this systematic review and meta-analysis was to summarize current best evidence on acupuncture and related therapies for palliative cancer care. Five international and 3 Chinese databases were searched. Randomized controlled trials (RCTs) comparing acupuncture and related therapies with conventional or sham treatments were considered. Primary outcomes included fatigue, paresthesia and dysesthesias, chronic pain, anorexia, insomnia, limb edema, constipation, and health-related quality of life, of which effective conventional interventions are limited. Thirteen RCTs were included. Compared with conventional interventions, meta-analysis demonstrated that acupuncture and related therapies significantly reduced pain (2 studies, n = 175, pooled weighted mean difference: -0.76, 95% confidence interval: -0.14 to -0.39) among patients with liver or gastric cancer. Combined use of acupuncture and related therapies and Chinese herbal medicine improved quality of life in patients with gastrointestinal cancer (2 studies, n = 111, pooled standard mean difference: 0.75, 95% confidence interval: 0.36-1.13). Acupressure showed significant efficacy in reducing fatigue in lung cancer patients when compared with sham acupressure. Adverse events for acupuncture and related therapies were infrequent and mild. Acupuncture and related therapies are effective in reducing pain, fatigue, and in improving quality of life when compared with conventional intervention alone among cancer patients. Limitations on current evidence body imply that they should be used as a complement, rather than an alternative, to conventional care. Effectiveness of acupuncture and related therapies for managing anorexia, reducing constipation, paresthesia and dysesthesia, insomnia, and limb edema in cancer patients is uncertain, warranting future RCTs in these areas.
C1 [Lau, Charlotte H. Y.] Chinese Univ Hong Kong, Fac Med, Hong Kong, Hong Kong, Peoples R China.
   [Wu, Xinyin; Chung, Vincent C. H.; Hui, Edwin P.; Wong, Samuel Y. S.; Lau, Alexander Y. L.; Sit, Regina S. T.; Wu, Justin C. Y.] Chinese Univ Hong Kong, Hong Kong Inst Integrat Med, Hong Kong, Hong Kong, Peoples R China.
   [Wu, Xinyin; Chung, Vincent C. H.; Liu, Xin; Wong, Samuel Y. S.; Sit, Regina S. T.] Chinese Univ Hong Kong, Jockey Club Sch Publ Hlth & Primary Care, Hong Kong, Hong Kong, Peoples R China.
   [Hui, Edwin P.] Chinese Univ Hong Kong, Comprehens Canc Trials Unit, Hong Kong, Hong Kong, Peoples R China.
   [Cramer, Holger] MitteUniv Duisburg Essen, Kliniken Essen, Fac Med, Dept Internal & Integrat Med, Essen, Germany.
   [Cramer, Holger] Univ Technol Sydney, Fac Hlth, ARCCIM, Sydney, NSW 2007, Australia.
   [Lau, Alexander Y. L.; Wu, Justin C. Y.] Chinese Univ Hong Kong, Dept Med & Therapeut, Hong Kong, Hong Kong, Peoples R China.
   [Ziea, Eric T. C.; Ng, Bacon F. L.] Hong Kong Hosp Author, Chinese Med Dept, Hong Kong, Hong Kong, Peoples R China.
C3 Chinese University of Hong Kong; Chinese University of Hong Kong; Chinese University of Hong Kong; Chinese University of Hong Kong; University of Technology Sydney; Chinese University of Hong Kong
RP Chung, VCH (corresponding author), Prince Wales Hosp, 4-F Sch Publ Hlth Bldg, Shatin, Hong Kong, Peoples R China.
EM vchung@cuhk.edu.hk
FU Hospital Authority of Hong Kong [8110016609]
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NR 47
TC 98
Z9 118
U1 4
U2 72
PU LIPPINCOTT WILLIAMS & WILKINS
PI PHILADELPHIA
PA TWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA
SN 0025-7974
EI 1536-5964
J9 MEDICINE
JI Medicine (Baltimore)
PD MAR 15
PY 2016
VL 95
IS 9
BP 
EP 
DI 10.1097/MD.0000000000002901
PG 13
WC Medicine, General & Internal
SC General & Internal Medicine
GA DK8WI
UT WOS:000375208900010
PM 26945382
DA 2026-01-16
ER

PT J
AU Hou, LL
   Xu, L
   Shi, Y
   Gu, F
AF Hou Lili
   Xu Lei
   Shi Yan
   Gu Fen
TI Effect of electric acupoint stimulation on gastrointestinal hormones and motility among geriatric postoperative patients with gastrointestinal tumors
SO JOURNAL OF TRADITIONAL CHINESE MEDICINE
LA English
DT Article
DE Electric stimulation therapy; Aged; Gastrointestinal stromal tumors; Gastrointestinal hormones; Gastrointestinal motility; Point ST36 (Zusanli); Point ST37 (Shangjuxu)
AB OBJECTIVE: To evaluate the effects of electric acupoint stimulation on gastrointestinal hormones and motility among geriatric postoperative patients with gastrointestinal tumors, and to explore an efficient and noninvasive method for postoperative recovery of bowel functions. METHODS: Forty patients were randomly and evenly assigned into a regular nursing care group (RNC) and an acupoint electric stimulation group (AES). Patients in the RNC group received regular nursing care and patients in the AES group received regular nursing care plus electric stimulation of acupoints. The serum levels of gastrin (GAS), motilin (MOT), and cholecystokinin (CCK), and an electrogastrogram (EGG) of all the patients were evaluated on the first, third, and fifth day after surgery. The time to first flatus after surgery and the number of patients with side effects such as abdominal pain, abdominal distention, and diarrhea were recorded. RESULTS: There were significant differences between the two groups in GAS, MOT, EGG, time to first flatus, abdominal pain, abdominal distention, and diarrhea (P < 0.05). CONCLUSION: Electric stimulation on acupoints could increase levels of GAS and MOT, promote the recovery of gastrointestinal functions, and decrease complications among postoperative senile patients with gastrointestinal tumors. (C) 2016 JTCM. All rights reserved.
C1 [Hou Lili] Shanghai Pulm Hosp, Dept Nursing, Shanghai 200433, Peoples R China.
   [Xu Lei] Shanghai Univ Tradit Chinese Med, Putuo Hosp, Dept Nursing, Shanghai 200062, Peoples R China.
   [Shi Yan] Tongji Univ, Peoples Hosp 10, Dept Nursing, Shanghai 200072, Peoples R China.
   [Gu Fen] Shanghai Pulm Hosp, Resp Dept, Shanghai 200433, Peoples R China.
C3 Shanghai University of Traditional Chinese Medicine; Tongji University
RP Shi, Y (corresponding author), Tongji Univ, Peoples Hosp 10, Dept Nursing, Shanghai 200072, Peoples R China.; Gu, F (corresponding author), Shanghai Pulm Hosp, Resp Dept, Shanghai 200433, Peoples R China.
EM hulizhikong@yahoo.com; gufen927@163.com
FU National Natural Science Foundation Project of China (Transcutaneous Electrical Acupoint Stimulation Prevents the Deep Vein Thrombosis: the Role of Endothelium Modulation) [81202750]
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NR 13
TC 23
Z9 24
U1 3
U2 22
PU JOURNAL TRADITIONAL CHINESE MED
PI BEIJING
PA 16 NANXIAOJIE, DONGZHIMEN NEI, BEIJING, 100700, PEOPLES R CHINA
SN 0255-2922
EI 1577-7014
J9 J TRADIT CHIN MED
JI J. Tradit. Chin. Med.
PD AUG 15
PY 2016
VL 36
IS 4
BP 450
EP 455
DI 
PG 6
WC Integrative & Complementary Medicine
SC Integrative & Complementary Medicine
GA DS8WV
UT WOS:000381064600006
PM 28459508
DA 2026-01-16
ER

PT J
AU Yue, P
   Gao, L
   Chen, M
   Guo, W
   Xin, SC
AF Yue, Ping
   Gao, Liang
   Chen, Mo
   Guo, Wen
   Xin, Sui-Cheng
TI [Effect of Warm-needle-moxibustion on Behavior Reactions and TNF-α and MMP-3
SO Zhen ci yan jiu = Acupuncture research
LA chi
DT Journal Article
AB OBJECTIVE: To observe the effect of warm-needle-moxibustion on behavior changes  and the levels of tumor necrosis factor-α (TNF-α) and matrix metalloproteinase-3  (MMP-3) in the knee cartilage tissue of rabbits with knee osteoarthritis (KOA) so  as to explore its mechanisms in relieving KOA. METHODS: Thirty male Japanese  white rabbits were randomly divided into normal, model and treatment groups (n=10  in each group). The KOA model was established by using immobilization me-thod.  The internal and external "Dubi" (ST 35), "Xuehai" (SP 10) and "Yanglingquan "(GB  34) were punctured with filiform needles first, followed by attaching an ignited  moxa column to the handle of each inserted needles. The treatment was conducted  for 20 min every time, once daily for 4 weeks. The behavioral scores were  assessed according to the pain severity, gait, joint motion range and articular  swelling severity in reference to the modified Lequesne's methods. The TNF-α and  MMP-3 contents in the knee joint cartilage tissue were assayed by  radioimmunoassay, and pathological changes of the articular cartilage tissue were  observed under microscope after sectioning and H.E. staining. RESULTS: The  Lequesne total score, and the cartilage TNF-α and MMP-3 contents were  significantly increased in the model group than in the normal group (P<0.05), and  obviously down-regulated after warm-needle-moxibustion intervention (P<0.05).  Under light microscope, the inflammatory infiltration of the articular cartilage  and the disordered arrangement of chondrocytes in KOA rabbits were improved in  the treatment group. CONCLUSIONS: Warm-needle-moxibustion intervention can  improve the motor function of rabbits with KOA, which may be related to its  effects in reducing the level of TNF-α and MMP-3 in articular cartilage tissue.
C1 School of Acu-moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing 100029, China.
   China Rehabilitation Research Center, Beijing 100068.
   Beijing Massage Hospital, Beijing 100035.
   School of Acu-moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing 100029, Chin.
   School of Acu-moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing 100029, Chin. pro_xinsch@163.com.
NR 0
TC 0
SN 
EI 1000-060
J9 Zhen Ci Yan Jiu
PD JUN 25
PY 2016
VL 41
IS 3
BP 235
EP 9
DI 
PG -226
WC Animals; Cartilage, Articular; chemistry; Knee Joint; Male; Matrix Metalloproteinase 3; analysis; Moxibustion; Osteoarthritis, Knee; therapy; Rabbits; Tumor Necrosis Factor-alpha; analysis
UT PubMed:29071912
PM 29071912
DA 2016-06-25
ER

PT J
AU Lee, PLT
   Tam, KW
   Yeh, ML
   Wu, WW
AF Lee, Phoebe Lyssandra Tan
   Tam, Ka-Wai
   Yeh, Mei-Ling
   Wu, Wei-Wen
TI Acupoint stimulation, massage therapy and expressive writing for breast cancer: A systematic review and meta-analysis of randomized controlled trials
SO COMPLEMENTARY THERAPIES IN MEDICINE
LA English
DT Review
DE Meta-analysis; Systematic review; Breast cancer; Acupoint stimulation; Massage therapy; Expressive writing; Pain; Anxiety; Quality of life
ID quality-of-life; sleep quality; double-blind; dual-center; women; acupuncture; fatigue; survivors; symptoms; depression
AB Researches have accumulated using non-pharmacologic interventions including acupoint stimulation, massage therapy and expressive writing to manage breast cancer-related symptoms. Results from randomized controlled trials (RCTs) can get contradictory. Objective: A systematic review and meta-analysis were conducted to determine the effects on the quality of life, negative emotions and disease-related symptoms among women with breast cancer. Methods: Two independent researchers performed a structured search using data sources including MEDLINE, CINAHL, Cochrane Central Register of Controlled Trials, EMBASE, PubMed and PsychINFO from the beginning of time until the first week of January 2015. A total of 23 acupoint stimulation, massage therapy and expressive writing RCTs were included in the review. Results: The study showed that no single intervention could be put under the spotlight exhibiting an overall effective result on all measured outcomes; however, looking into each one in detail shows different results in specific outcomes. Among the three interventions, acupoint stimulation has a treatment effect for general pain (MD = -1.46, 95% CI = -2.38 to -0.53) and fatigue (MD = -2.22, 95% CI = -3.68 to -0.77), massage therapy has a treatment effect for anxiety (MD = -0.50, 95% CI = -0.77 to -0.24), and expressive writing has a treatment effect for quality of life (MD = 7.18, 95% Cl = 0.38 to 13.98). The measurement other outcomes showed either ineffective or equivocal results. Conclusion: Non-pharmacologic interventions including acupoint stimulation, massage therapy and expressive writing have an effect on a middle-age woman with breast cancer. However, because of limitations, the seemingly promising results should be interpreted with caution. (C) 2016 Elsevier Ltd. All rights reserved.
C1 [Lee, Phoebe Lyssandra Tan; Wu, Wei-Wen] Natl Taipei Univ Nursing & Hlth Sci, Sch Nursing, Coll Nursing, 365 Min Te Rd, Taipei 11219, Taiwan.
   [Tam, Ka-Wai] Taipei Med Univ, Sch Med, Dept Surg, Coll Med, Taipei, Taiwan.
   [Tam, Ka-Wai] Taipei Med Univ, Div Gen Surg, Dept Surg, Shuang Ho Hosp, 250 Wu Hsing St, Taipei 11031, Taiwan.
   [Yeh, Mei-Ling] Natl Taipei Univ Nursing & Hlth Sci, Grad Inst Integrat Tradit Chinese Med Western Nur, Coll Nursing, 365 Min Te Rd, Taipei 11219, Taiwan.
C3 National Taipei University of Nursing & Health Science (NTUNHS); Taipei Medical University; Taipei Medical University; Shuang Ho Hospital; National Taipei University of Nursing & Health Science (NTUNHS)
RP Yeh, ML (corresponding author), Natl Taipei Univ Nursing & Hlth Sci, Grad Inst Integrat Tradit Chinese Med Western Nur, Coll Nursing, 365 Min Te Rd, Taipei 11219, Taiwan.
EM phoebeelee@gmail.com; kelvintam@h.tmu.edu.tw; meiling@ntunhs.edu.tw; weiwen@ntunhs.edu.tw
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NR 64
TC 28
Z9 37
U1 1
U2 53
PU CHURCHILL LIVINGSTONE
PI EDINBURGH
PA JOURNAL PRODUCTION DEPT, ROBERT STEVENSON HOUSE, 1-3 BAXTERS PLACE, LEITH WALK, EDINBURGH EH1 3AF, MIDLOTHIAN, SCOTLAND
SN 0965-2299
EI 1873-6963
J9 COMPLEMENT THER MED
JI Complement. Ther. Med.
PD AUG 15
PY 2016
VL 27
IS 
BP 87
EP 101
DI 10.1016/j.ctim.2016.06.003
PG 15
WC Integrative & Complementary Medicine
SC Integrative & Complementary Medicine
GA DU7PZ
UT WOS:000382408400014
PM 27515882
DA 2026-01-16
ER

PT J
AU Lee, PL
   Tam, KW
   Yeh, ML
   Wu, WW
AF Lee, Phoebe Lyssandra Tan
   Tam, Ka-Wai
   Yeh, Mei-Ling
   Wu, Wei-Wen
TI Acupoint stimulation, massage therapy and expressive writing for breast cancer: A
SO Complementary therapies in medicine
LA English
DT Journal Article
DE Acupoint stimulation; Anxiety; Breast cancer; Expressive writing; Massage therapy; Meta-analysis; Pain; Quality of life; Systematic review
AB Researches have accumulated using non-pharmacologic interventions including  acupoint stimulation, massage therapy and expressive writing to manage breast  cancer-related symptoms. Results from randomized controlled trials (RCTs) can get  contradictory. OBJECTIVE: A systematic review and meta-analysis were conducted to  determine the effects on the quality of life, negative emotions and  disease-related symptoms among women with breast cancer. METHODS: Two independent  researchers performed a structured search using data sources including MEDLINE,  CINAHL, Cochrane Central Register of Controlled Trials, EMBASE, PubMed and  PsychINFO from the beginning of time until the first week of January 2015. A  total of 23 acupoint stimulation, massage therapy and expressive writing RCTs  were included in the review. RESULTS: The study showed that no single  intervention could be put under the spotlight exhibiting an overall effective  result on all measured outcomes; however, looking into each one in detail shows  different results in specific outcomes. Among the three interventions, acupoint  stimulation has a treatment effect for general pain (MD=-1.46, 95% CI=-2.38 to  -0.53) and fatigue (MD=-2.22, 95% CI=-3.68 to -0.77), massage therapy has a  treatment effect for anxiety (MD=-0.50, 95% CI=-0.77 to -0.24), and expressive  writing has a treatment effect for quality of life (MD=7.18, 95% CI=0.38 to  13.98). The measurement other outcomes showed either ineffective or equivocal  results. CONCLUSION: Non-pharmacologic interventions including acupoint  stimulation, massage therapy and expressive writing have an effect on a  middle-age woman with breast cancer. However, because of limitations, the  seemingly promising results should be interpreted with caution.
C1 School of Nursing, College of Nursing, National Taipei University of Nursing and Health Sciences, No. 365 Min-Te Road, Taipei 11219, Taiwan, ROC. Electronicaddress: phoebeelee@gmail.com.
   Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taiwan, ROC
   Division of General Surgery, Department of Surgery,Taipei Medical University-Shuang Ho Hospital, No. 250, Wu-Hsing Street., Wu-HsingDistrict, Taipei 11031, Taiwan, ROC. 
   Graduate Institute of Integration of Traditional Chinese Medicine with Western Nursing, College of Nursing, National Taipei University of Nursing & HealthSciences, No. 365, Min-Te Road, Taipei 11219, Taiwan, ROC. 
   School of Nursing, College of Nursing, National Taipei University of Nursing and Health Sciences, No. 365 Min-Te Road, Taipei 11219, Taiwan, ROC. Electronicaddress: weiwen@ntunhs.edu.tw.
EM eiling@ntunhs.edu.tw
NR 0
TC 0
SN 1873-696
EI 
J9 Complement Ther Med
PD AUG 16
PY 2016
VL 27
IS 
BP 87
EP 101
DI 10.1016/j.ctim.2016.06.003
PG 14
WC Acupuncture Points; Adult; Aged; Aged, 80 and over; Breast Neoplasms; physiopathology; Female; Humans; Massage; psychology; Middle Aged; Randomized Controlled Trials as Topic; Writing
UT PubMed:27515882
PM 27515882
DA 2016-08-16
ER

PT J
AU de Valois, B
   Asprey, A
   Young, T
AF de Valois, Beverley
   Asprey, Anthea
   Young, Teresa
TI "The Monkey on Your Shoulder": A Qualitative Study of Lymphoedema Patients' Attitudes to and Experiences of Acupuncture and Moxibustion
SO EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
LA English
DT Article
ID alternative medicine use; breast-cancer patients; of-life; secondary lymphedema; psychosocial impact; hot flashes; head; complementary; symptoms; feasibility
AB Background. Lymphoedema, a distressing consequence of cancer treatment, has significant negative impact on health-related quality of life. Multidisciplinary approaches are needed to improve physical and psychosocial wellbeing. Acupuncture and moxibustion (acu/moxa), two modalities of traditional East Asian medicine, may contribute to improved outcomes for cancer survivors with lymphoedema. Aim. To explore how patients with lymphoedema secondary to cancer treatment perceive and experience acu/moxa treatment. Design and Setting. A qualitative focus group study, nested in a 3-step mixed methods observational study, was carried out in a cancer drop-in and information centre in north-west London. Methods. Six focus groups and one telephone interview were conducted with 23 survivors of breast or head and neck cancer, who had completed up to 13 acu/moxa treatments. Scripts were transcribed, coded, and analysed to identify salient and overarching themes. Results. Participants described feeling disempowered by cancer treatment and subsequent diagnosis of lymphoedema. Acu/moxa was valued for its whole-person approach and for time spent with a practitioner who cared, listened, and responded. Participants reported changes in physical and psychosocial health, including increased energy levels and reduced pain and discomfort, and feelings of empowerment, personal control, and acceptance. Many were motivated to improve self-care. Conclusion. Many participants who received acu/moxa treatment reported improved wellbeing and a more proactive attitude towards self-care.
C1 [de Valois, Beverley; Young, Teresa] Mt Vernon Canc Ctr, Lynda Jackson Macmillan Ctr, Support Oncol Res Team, Rickmansworth Rd, Northwood HA6 2RN, Middx, England.
   [Asprey, Anthea] Univ Exeter, Sch Med, Magdalen Rd, Exeter EX1 2LU, Devon, England.
C3 Mount Vernon Cancer Centre; University of Exeter
RP de Valois, B (corresponding author), Mt Vernon Canc Ctr, Lynda Jackson Macmillan Ctr, Support Oncol Res Team, Rickmansworth Rd, Northwood HA6 2RN, Middx, England.
EM beverley.devalois@nhs.net
FU National Institute for Health Research (NIHR) under its Research for Innovation, Speculation and Creativity (RISC) Programme [PB-PG-0407-10086]
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NR 57
TC 6
Z9 8
U1 0
U2 21
PU HINDAWI LTD
PI LONDON
PA ADAM HOUSE, 3RD FLR, 1 FITZROY SQ, LONDON, W1T 5HF, ENGLAND
SN 1741-427X
EI 1741-4288
J9 EVID-BASED COMPL ALT
JI Evid.-based Complement Altern. Med.
PD JUN 15
PY 2016
VL 2016
IS 
BP 
EP 
DI 10.1155/2016/4298420
PG 14
WC Integrative & Complementary Medicine
SC Integrative & Complementary Medicine
GA DU2OL
UT WOS:000382050300001
PM 27630734
DA 2026-01-16
ER

PT J
AU Wong, R
   Major, P
   Sagar, S
AF Wong, Raimond
   Major, Pierre
   Sagar, Stephen
TI Phase 2 Study of Acupuncture-Like Transcutaneous Nerve Stimulation for
SO Integrative cancer therapies
LA English
DT Journal Article
DE ALTENS; Acupuncture; TENS; chemotherapy; neuropathy
AB A prospective phase 2 study was conducted to evaluate the clinical utility of  acupuncture-like transcutaneous nerve stimulation (ALTENS) for the treatment of  chemotherapy-induced peripheral neuropathy (CIPN). Eligible cancer patients had a  < 2 ECOG performance score, received neurotoxic chemotherapy, and developed CIPN  symptoms for > two months. Randomization was used to eliminate bias in patient  selection for ALTENS and was not to compare the effectiveness between the two  treatments.ALTENS treatments were delivered using Codetron units. Bilateral  acupuncture points included LI4 and LIV3, plus LI11 or ST36 were stimulated.  Acupuncture treatments were administered to CV6, SP6, ST6, LI11, Bafeng, Baxie  and selective Jing points bilaterally. Twelve treatments were delivered twice  weekly over 6 to 8 weeks. The Modified Total Neuropathy Score (mTNS), Numbness  Score, and Edmonton Symptom Assessment Score (ESAS) were assessed at baseline,  treatment completion, plus at 3 and 6 months follow-up. The primary study  endpoint was mTNS score at 6 months. We planned to recruit 23 patients into each  group. After 30 patients were recruited, 2 were lost to follow-up at 3 months in  the ALTENS group and 3 in the acupuncture group. The research team decided to  recruit all remaining consecutive patients only to the ALTENS group to ensure an  adequate evaluation of ALTENS, the primary object of evaluation. There were 27  patients in the ALTENS group, with an average symptom duration of 10 months after  chemotherapy. Twenty four and 23 patients completed the 3 and 6 month follow-up  respectively. The median mTNS scores were 7.1, 4.0, 3.6 and 3.1 at baseline,  treatment completion, 3 and 6 months follow-up, respectively. One-way ANOVA  analysis showed a significant improvement in mTNS scores (p<0.001) at 6 months.  Numbness scores were also significantly improved at 6 months. ESAS pain scores  and perception of well-being scores analyses were inconclusive. There were no  significant reported side effects of ALTENS. There were only 13 patients in the  acupuncture group and the number was insufficient for either an independent or a  comparative analysis. The results of this study suggests that ALTENS  significantly reduces the mTNS scores and numbness in patients suffering from  CIPN symptoms.
C1 McMaster University-Juravinski Cancer Centre, Hamilton, ON, Canada wongrai@hhsc.ca.
   McMaster University-Juravinski Cancer Centre, Hamilton, ON, Canada.
   McMaster University-Juravinski Cancer Centre, Hamilton, ON, Canada.
NR 0
TC 0
SN 1552-695
EI 1534-735
J9 Integr Cancer Ther
PD MAY 1
PY 2016
VL 15
IS 2
BP 153
EP 64
DI 10.1177/1534735415627926
PG -89
WC Acupuncture Therapy; methods; Adult; Aged; Antineoplastic Agents; adverse effects; Female; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasms; drug therapy; Peripheral Nervous System Diseases; chemically induced; Prospective Studies; Transcutaneous Electric Nerve Stimulation; methods
UT PubMed:27130723
PM 27130723
DA 2016-05-01
ER

PT J
AU Kim, KH
   Kim, DH
   Kim, HY
   Son, GM
AF Kim, Kun Hyung
   Kim, Dae Hun
   Kim, Hee Young
   Son, Gyung Mo
TI Acupuncture for recovery after surgery in patients undergoing colorectal cancer resection: a systematic review and meta-analysis
SO ACUPUNCTURE IN MEDICINE
LA English
DT Review
ID enhanced recovery; perioperative acupuncture; postoperative analgesia; electroacupuncture; pain; stimulation; motility; challenges; outcm; impact
AB Objective To assess the efficacy/effectiveness and safety of acupuncture in patients recovering from colorectal cancer resection. Methods We systematically searched four English language databases (Medline, Embase, CENTRAL (Cochrane Central Register of Controlled Trials), and AMED (Allied and Complementary Medicine Database)) and one Chinese database (CAJ, China Academic Journals). Randomised trials of acupuncture compared with usual/routine care, sham interventions or active comparators in patients undergoing colorectal cancer resection were eligible for inclusion. Postoperative symptoms and quality of life (QoL) were the primary outcomes for the review. Results Of 1225 screened hits, seven randomised trials with 540 participants were included. High or uncertain risk of bias and significant heterogeneity were observed. All outcomes were measured before discharge, and no trial explicitly reported post-discharge outcomes. The response to acupuncture in terms of postoperative symptoms was inconsistent across trials. QoL was not measured in the included studies. For certain outcomes reflecting physiological recovery, favourable effects of acupuncture were observed compared with sham acupuncture, namely time to first flatus (n=207, three studies; mean difference (MD) -7.48 h, 95% CI -14.58 to -0.39 h, I-2=0%) and time to first defaecation (n=149, two studies; MD -18.04 h, 95% CI -31.90 to -4.19 h, I-2=0%). Two studies reported there were no acupuncture-related adverse events, whereas the remaining studies did not consider adverse events. Conclusions We found low-to moderate-quality evidence for the efficacy and safety of acupuncture for recovery after surgery in colorectal cancer patients. Future trials with adequate allocation concealment, blinding of outcome assessors, and measurement of post-discharge outcomes including QoL or functional recovery are warranted.
C1 [Kim, Kun Hyung] Pusan Natl Univ, Sch Korean Med, Yangsan, South Korea.
   [Kim, Dae Hun] Pusan Natl Univ, Korean Med Hosp, Dept Acupuncture & Moxibust, Yangsan, South Korea.
   [Kim, Hee Young] Pusan Natl Univ, Yangsan Hosp, Dept Anesthesia & Pain Med, Yangsan, South Korea.
   [Son, Gyung Mo] Pusan Natl Univ, Yangsan Hosp, Dept Surg, Yangsan 50612, South Korea.
C3 Pusan National University; Pusan National University; Pusan National University; Pusan National University Hospital; Pusan National University; Pusan National University Hospital
RP Son, GM (corresponding author), Pusan Natl Univ, Yangsan Hosp, Dept Surg, Yangsan 50612, South Korea.
EM skm171@empas.com
FU National Research Foundation of Korean Government [2014R1A5A2009936]; Korea Institute of Oriental Medicine [K16123]
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NR 40
TC 35
Z9 39
U1 0
U2 33
PU SAGE PUBLICATIONS LTD
PI LONDON
PA 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND
SN 0964-5284
EI 1759-9873
J9 ACUPUNCT MED
JI Acupunct. Med.
PD AUG 15
PY 2016
VL 34
IS 4
BP 248
EP 256
DI 10.1136/acupmed-2015-010941
PG 9
WC Integrative & Complementary Medicine
SC Integrative & Complementary Medicine
GA DW9RE
UT WOS:000383998600002
PM 26921418
DA 2026-01-16
ER

PT J
AU Kennedy, L
   Gonzales, E
   Corbin, L
AF Kennedy, Laura
   Gonzales, Erin
   Corbin, Lisa
TI THE EFFECT OF CURANDERISMO ON CHRONIC NON-MALIGNANT PAIN: A CASE REPORT
SO EXPLORE-THE JOURNAL OF SCIENCE AND HEALING
LA English
DT Article
DE curanderismo; indigenous medicine; complementary medicine; chronic pain
ID low-back-pain; complementary; acupuncture; massage; therapy; folk
AB This case study describes the effects of the use of curanderismo, an indigenous healing modality combining techniques in massage, sound, and aromatherapy, on a patient with chronic pain. Despite being a commonly used health practice in certain populations, little is reported in the medical literature about the use of curanderismo. Case report as part of a larger randomized trial of curanderismo for chronic pain. Setting was a community-based hospital affiliated primary care clinic. An adult patient with chronic, opioid dependent back pain following an injury, and subsequent spinal fusion was treated. Intervention was the patient received 33 curanderismo treatment sessions over 10 months in addition to ongoing conventional treatment at a community-based chronic pain management clinic. Main outcomes measures were self-reported assessments of pain, functional ability, mood, insomnia, and narcotic usage. Secondary outcome measure was qualitative interview. Although there was no change in quantitative self-reported pain measures, the patient reported improved function, mood, and sleep as well as decreased narcotic usage. Curanderismo, in addition to conventional pain management, improved patient reported symptoms and functional ability, led to healthy lifestyle changes, and decreased narcotic usage. Controlled studies are needed to confirm the benefit of curanderismo as safe, non-interventional, and cost-effective adjunct for chronic pain management.
C1 [Kennedy, Laura; Gonzales, Erin] Univ Colorado, Sch Med, Anschutz Med Campus,Bldg 500-13001,E 17th Pl, Aurora, CO 80045 USA.
   [Corbin, Lisa] Univ Colorado Hosp, Ctr Integrat Med, 3055 Rosyln St,Suite 250, Denver, CO 80238 USA.
   [Corbin, Lisa] Univ Colorado, Dept Internal Med, Div Gen Internal Med, Sch Med,Acad Off 1, Anschutz Med Campus,8th Floor,Mailstop B180, Aurora, CO 80045 USA.
C3 University of Colorado System; University of Colorado Anschutz Medical Campus; University of Colorado System; University of Colorado Hospital; University of Colorado System; University of Colorado Anschutz Medical Campus
RP Corbin, L (corresponding author), Univ Colorado Hosp, Ctr Integrat Med, 3055 Rosyln St,Suite 250, Denver, CO 80238 USA.; Corbin, L (corresponding author), Univ Colorado, Dept Internal Med, Div Gen Internal Med, Sch Med,Acad Off 1, Anschutz Med Campus,8th Floor,Mailstop B180, Aurora, CO 80045 USA.
EM lisa.corbin@ucdenver.edu
FU AlterMed Research Foundation
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NR 28
TC 6
Z9 9
U1 0
U2 14
PU ELSEVIER SCIENCE INC
PI NEW YORK
PA STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA
SN 1550-8307
EI 1878-7541
J9 EXPLORE-NY
JI Explore-J Sci. Heal.
PD JUL-AUG 15
PY 2016
VL 12
IS 4
BP 263
EP 267
DI 10.1016/j.explore.2016.04.006
PG 5
WC Integrative & Complementary Medicine
SC Integrative & Complementary Medicine
GA DQ1RC
UT WOS:000378977100015
PM 27198039
DA 2026-01-16
ER

PT J
AU Brooks, MR
   Golianu, B
AF Brooks, Meredith R.
   Golianu, Brenda
TI Perioperative management in children with chronic pain
SO PEDIATRIC ANESTHESIA
LA English
DT Review
DE pediatric; children; chronic pain; perioperative management; opioid-tolerant; surgical
ID pediatric chronic pain; postoperative pain; serotonin syndrome; double-blind; regional anesthesia; total knee; functional connectivity; lidocaine infusion; neuropathic pain; opioid-tolerant
AB Children with chronic pain often undergo surgery and effective perioperative management of their pain can be challenging. Identification of the pediatric chronic pain patient preoperatively and development of a perioperative pain plan may help ensure a safer and more comfortable perioperative course. Successful management usually requires multiple different classes of analgesics, regional anesthesia, and adjunctive nonpharmacological therapies. Neuropathic and oncological pain can be especially difficult to treat and usually requires an individualized approach.
C1 [Brooks, Meredith R.] Cook Childrens Hosp, Dept Anesthesiol, 901 Seventh Ave, Ft Worth, TX 76104 USA.
   [Golianu, Brenda] Stanford Univ, Sch Med, Dept Anesthesiol Perioperat & Pain Med, Stanford, CA 94305 USA.
C3 Cook Children's Medical Center; Stanford University
RP Brooks, MR (corresponding author), Cook Childrens Hosp, Dept Anesthesiol, 901 Seventh Ave, Ft Worth, TX 76104 USA.
EM meredith.brooks@cookchildrens.org
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NR 147
TC 6
Z9 7
U1 0
U2 14
PU WILEY
PI HOBOKEN
PA 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
SN 1155-5645
EI 1460-9592
J9 PEDIATR ANESTH
JI Pediatr. Anesth.
PD AUG 15
PY 2016
VL 26
IS 8
BP 794
EP 806
DI 10.1111/pan.12948
PG 13
WC Anesthesiology; Pediatrics
SC Anesthesiology; Pediatrics
GA DR4ZZ
UT WOS:000379913900003
PM 27370517
DA 2026-01-16
ER

